depig-f cream - Hydroquinone (4% w/w) medicine

depig-f cream - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Intermed Pharma Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jul 2, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jul 02, 2026

What is depig-f cream used for?

Adoclear HQ Cream (Hydroquinone) is used to treat DERMA. It contains Hydroquinone (4% w/w), which Inhibits tyrosinase, an enzyme involved in melanin synthesis, thereby reducing m. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Hydroquinone
  • Manufacturer: Intermed Pharma Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š depig-f cream Uses & Benefits

Treatment of hyperpigmentation disorders such as melasma, freckles, age spots, and post-inflammatory hyperpigmentation.

Off-label uses: Treatment of lentigo, Acne hyperpigmentation

๐Ÿ“‹ Drug Information

Generic Name(s)Hydroquinone
Brand NameAdoclear HQ Cream
ManufacturerIntermed Pharma Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassAnti Pigmentation & Skin lightening agent
Route of AdministrationTopical
StorageStore at room temperature (20-25ยฐC), protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionTopical absorption through skin; systemic absorption minimal but can occur with prolonged use on large areas.
DistributionDistributes into skin layers; systemic distribution limited.
Protein BindingNot well characterized; likely low.
MetabolismMetabolized in the liver primarily via conjugation to glucuronide and sulfate.
Half-LifeNot well defined; systemic half-life estimated at 6-8 hours.
ExcretionRenal excretion of metabolites.
BioavailabilityLow systemic bioavailability due to topical application.
Onset of Action2-4 weeks for visible lightening.
Peak Plasma TimeNot applicable for topical use.
Duration of ActionEffects persist with continued use; reversible upon discontinuation.

How It Works

Inhibits tyrosinase, an enzyme involved in melanin synthesis, thereby reducing melanin production.

Mechanism Steps

1Hydroquinone penetrates the skin and enters melanocytes.
2It inhibits the enzyme tyrosinase, which catalyzes the conversion of tyrosine to melanin.
3Reduction in melanin synthesis leads to lightening of hyperpigmented areas.

๐Ÿ’ก How to Take depig-f cream

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of depig-f cream

โœ… Common Side Effects

  • Mild skin irritation
  • Redness
  • Dryness
  • Stinging

๐Ÿšจ Serious Side Effects

  • Severe allergic reaction
  • Skin discoloration (ochronosis)
  • Blistering

โš ๏ธ Rare Side Effects

  • Exogenous ochronosis
  • Nail discoloration

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Benzoyl peroxide Major Increased risk of skin irritation and oxidation of hydroquinone.
Hydrogen peroxide Major Increased skin irritation and reduced efficacy.
Corticosteroids Moderate May enhance skin thinning and irritation.
Retinoids Moderate Increased skin irritation and photosensitivity.

๐Ÿšจ Major Interactions

  • Benzoyl peroxide
  • Hydrogen peroxide
  • Other depigmenting agents

โšก Moderate Interactions

  • Corticosteroids
  • Retinoids

โ„น๏ธ Minor Interactions

  • Sunscreens
  • Moisturizers

๐Ÿท Alcohol Interaction

No known interaction.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to hydroquinone, pre-existing skin conditions (e.g., vitiligo), use on broken or irritated skin.

๐Ÿ“Š Monitoring Parameters

Skin condition, signs of irritation or allergic reaction, improvement in pigmentation.

๐Ÿคฑ Lactation Safety

Not recommended; avoid use during breastfeeding.

๐Ÿ’Š Overdose Management

Topical overdose unlikely; if ingested, induce vomiting and seek medical attention.

โฐ Missed Dose

Apply as soon as remembered; skip if almost time for next dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jul 02, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for depig-f cream

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Alternative brands with exact same active ingredient (Hydroquinone (4% w/w)):

Medical Note: Always consult your doctor before switching medications.

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