A nutraceutical/ethical pharmaceutical combination product containing a micronized form of the adrenal prohormone Dehydroepiandrosterone (DHEA) and the biologically active form of folate, L-Methylfolate. DHEA serves as a precursor to androgens and estrogens, while L-Methylfolate is critical for methylation processes and neurotransmitter synthesis. This combination is primarily used to address age-related decline in DHEA levels and support neurological and cardiovascular health, particularly in individuals with folate metabolism impairments.
Adult Dosage: One tablet daily, preferably in the morning with food. Dose of DHEA should be individualized based on serum DHEA-S levels. 75mg is a common supplemental dose.
Instructions: Administer orally with a meal to enhance absorption and reduce potential gastrointestinal upset. Swallow whole with a glass of water. Do not crush or chew. Avoid taking late in the evening as DHEA may cause insomnia in some individuals.
DHEA is an endogenous steroid hormone precursor produced by the adrenal glands. It is converted peripherally into androgens (like testosterone) and estrogens (like estradiol), exerting its effects through these downstream hormones. It also has weak androgenic activity itself. L-Methylfolate (5-MTHF) is the biologically active form of folate that crosses the blood-brain barrier. It is a critical cofactor in the synthesis of neurotransmitters (serotonin, dopamine, norepinephrine) via the methylation cycle and in the conversion of homocysteine to methionine.