Aspirin + Rosuvastatin + Clopidogrel Capsule: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit, or black tarry stools
- Severe abdominal pain or persistent vomiting
- Sudden severe headache, confusion, weakness, or difficulty speaking
- Chest pain or difficulty breathing
- Severe muscle pain, tenderness, or dark urine
- Yellowing of skin or eyes, or right upper abdominal pain
- Sudden swelling of face, lips, or throat
- Unusual bruising or bleeding that does not stop
If experiencing severe symptoms, call emergency services immediately.
What is davaindia aspirin+rosuvastatin+clopidogrel 150mg/20mg/75mg capsule used for?
This medicine is a combination of aspirin, rosuvastatin, and clopidogrel used to prevent heart attacks and strokes in high-risk patients. It works by reducing platelet clumping and lowering cholesterol. It is taken once daily with food, and must only be used under medical supervision.
- Generic Name: Aspirin + Rosuvastatin
- Manufacturer: Davaindia Generic Pharmacy
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 davaindia aspirin+rosuvastatin+clopidogrel 150mg/20mg/75mg capsule के बारे में (Hindi Summary)
उपयोग: यह दवा एस्पिरिन, रोसुवास्टेटिन और क्लोपिडोग्रेल का संयोजन है। इसका उपयोग उन रोगियों में दिल का दौरा, स्ट्रोक और रक्त वाहिकाओं की रुकावट को रोकने के लिए किया जाता है जिन्हें पहले से हृदय रोग या स्ट्रोक हो चुका है। यह खून के थक्के बनने को कम करती है और कोलेस्ट्रॉल को नियंत्रित करती है। इसे डॉक्टर की सलाह के बिना शुरू या बंद नहीं करना चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में पेट में जलन, मतली, आसानी से चोट लगना या नाक से खून आना, मांसपेशियों में दर्द और सिरदर्द शामिल हैं। गंभीर दुष्प्रभावों में पेट या आंतों से खून बहना, मस्तिष्क में रक्तस्राव, गंभीर मांसपेशियों की क्षति और लीवर की समस्या हो सकती है। कोई भी असामान्य रक्तस्राव, काला मल, उल्टी में खून, या पेशाब का रंग गहरा होने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार रोज एक बार भोजन के साथ लें। इसे चबाएं या तोड़ें नहीं। डॉक्टर की सलाह के बिना इसे अचानक बंद न करें, क्योंकि इससे दिल का दौरा या स्ट्रोक का खतरा बढ़ सकता है। शराब न पिएं। कोई भी नई दवा शुरू करने से पहले डॉक्टर से पूछें। किसी भी सर्जरी या दांत के इलाज से पहले अपने डॉक्टर को इस दवा के बारे में बताएं। नियमित जांच कराते रहें।
💊 davaindia aspirin+rosuvastatin+clopidogrel 150mg/20mg/75mg capsule Uses & Benefits
[{"condition":"Secondary prevention after acute coronary syndrome","description":"Used to reduce the risk of another heart attack, stroke, or death in patients who have already had a heart attack or unstable angina.","evidence":"Well-established"},{"condition":"Post-stroke or transient ischaemic attack (TIA) prevention","description":"Helps prevent recurrent clot-related strokes and transient ischaemic attacks in selected patients.","evidence":"Well-established"},{"condition":"Peripheral arterial disease","description":"Reduces the risk of cardiovascular events in patients with narrowed arteries in the legs.","evidence":"Established"},{"condition":"Post-coronary stent placement","description":"Used as part of dual antiplatelet therapy along with cholesterol control after stent insertion.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Primary prevention in very high-risk individuals without prior events","description":"Sometimes considered in patients with multiple risk factors and very high calculated cardiovascular risk, but only after careful specialist assessment.","evidence":"Limited"}]
Primary treatment for: Cardiovascular disease prevention (secondary prevention after heart attack, stroke, or peripheral arterial disease)
Also treats: Hypercholesterolaemia, Coronary artery disease, Cerebrovascular disease, Peripheral arterial disease, Post-stent thrombosis prevention
📋 Drug Information
| Generic Name(s) | Aspirin + Rosuvastatin |
| Brand Name | Azuva 20-Gold Capsule |
| Manufacturer | Davaindia Generic Pharmacy |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Antiplatelet + HMG-CoA Reductase Inhibitor |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C in a dry place, away from direct sunlight and moisture. Keep the capsule in its original blister pack or container until it is time to take it. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the pack. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. Guidelines generally recommend dual antiplatelet therapy and statin therapy in selected high-risk patients, but the exact combination and duration must be decided by a specialist. |
| ICMR Guideline | Not established from the available information. Indian guidelines recommend antiplatelet and statin therapy for secondary prevention, but the specific fixed-dose combination should be used only under specialist supervision. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines three complementary actions. Aspirin irreversibly inhibits cyclooxygenase-1 in platelets, blocking thromboxane A2 production and reducing platelet clumping. Clopidogrel is a prodrug that is converted in the liver to an active metabolite which irreversibly blocks the P2Y12 ADP receptor on platelets, further preventing activation and aggregation. Rosuvastatin inhibits HMG-CoA reductase in the liver, reducing cholesterol synthesis, increasing LDL receptor activity, and lowering LDL cholesterol, while also stabilising atherosclerotic plaques and reducing vascular inflammation.
Mechanism Steps
💡 How to Take davaindia aspirin+rosuvastatin+clopidogrel 150mg/20mg/75mg capsule
Strength: Capsule containing aspirin 150 mg, rosuvastatin 20 mg, and clopidogrel 75 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one capsule taken orally once daily, preferably with food. However, the exact dose and duration must be individualized by a qualified clinician based on the indication, age, weight, kidney function, liver function, bleeding risk, and other medicines being taken. Never adjust the dose yourself. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the bleeding and muscle-related side effects of this medicine. The dose is usually the same as for younger adults, but kidney and liver function should be checked more often, and the doctor may adjust or avoid the medicine if the risk of bleeding is high. |
| Renal Impairment | In patients with mild to moderate kidney impairment, no dose adjustment is usually needed, but kidney function should be monitored. In severe kidney impairment (eGFR less than 30 mL/min/1.73 m2), rosuvastatin is contraindicated and the combination should generally be avoided. Always follow your doctor's advice. |
| Hepatic Impairment | This medicine should be avoided in patients with active liver disease or unexplained persistent elevations of liver enzymes. In mild to moderate liver impairment, the doctor may reduce the dose or choose alternative medicines. Regular liver function tests are required. |
| Maximum Daily Dose | The maximum daily dose is one capsule containing aspirin 150 mg, rosuvastatin 20 mg, and clopidogrel 75 mg, unless a specialist prescribes otherwise. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of davaindia aspirin+rosuvastatin+clopidogrel 150mg/20mg/75mg capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ibuprofen | Major | |
| Omeprazole | Major | |
| Methotrexate | Major | |
| Ciclosporin | Major | |
| Gemfibrozil | Moderate | |
| Fluconazole | Moderate | |
| SSRIs | Moderate | |
| Antacids | Minor | |
| Ginkgo biloba | Minor |
🚨 Major Interactions
- Warfarin and other anticoagulants
- NSAIDs (e.g., ibuprofen, naproxen, diclofenac)
- Omeprazole and esomeprazole
- Methotrexate
- Ciclosporin
⚡ Moderate Interactions
- Gemfibrozil and other fibrates
- Protease inhibitors (e.g., ritonavir, atazanavir)
- Colchicine
- Fluconazole, ketoconazole, and other CYP2C19 inhibitors
- SSRIs and SNRIs
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. It increases the risk of gastrointestinal bleeding caused by aspirin and clopidogrel, and it adds to the liver strain caused by rosuvastatin. If you drink alcohol regularly, discuss this with your doctor so that your liver and bleeding risk can be monitored.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Active bleeding or bleeding disorders such as haemophilia","Active peptic ulcer or recent gastrointestinal bleeding","Severe liver disease or unexplained persistent high liver enzymes","Known allergy to aspirin, clopidogrel, rosuvastatin, or any ingredient","Pregnancy and breastfeeding unless specifically advised by a specialist","Children and adolescents under 16 years","Severe kidney disease with eGFR less than 30 mL/min/1.73 m2 (rosuvastatin contraindicated)","Concurrent use with strong CYP2C19 inhibitors or certain antivirals"]
⚠️ Warnings & Precautions
["Do not stop this medicine suddenly without talking to your doctor, as this can increase the risk of heart attack or stroke.","Tell all healthcare providers, including dentists, that you are taking this medicine before any procedure.","Avoid alcohol and NSAIDs to reduce bleeding risk.","Report unusual bleeding, bruising, muscle pain, or dark urine immediately.","Use effective contraception during treatment if you are of childbearing potential.","Avoid grapefruit juice in large amounts.","Use with caution in elderly patients and those with kidney or liver disease.","Do not take this medicine if you have an active infection with fever without consulting your doctor."]
🤱 Lactation Safety
Not established from the available information. Aspirin and rosuvastatin may pass into breast milk and could harm a nursing infant. Clopidogrel data are limited. Breastfeeding is generally not recommended while taking this medicine unless a specialist advises otherwise.
💊 Overdose Management
Overdose can cause severe bleeding, stomach pain, vomiting, ringing in the ears, dizziness, and liver or kidney damage. If you suspect an overdose, seek emergency medical care immediately. Treatment is supportive and may include stomach emptying, activated charcoal, vitamin K, platelet transfusion, or other measures as decided by the treating doctor. Do not try to treat yourself at home.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose. If you are unsure, contact your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as prescribed, usually once daily with food to reduce stomach irritation. Do not crush, chew, or open the capsule unless your doctor specifically tells you to. Never stop this medicine on your own, because sudden discontinuation can increase the risk of heart attack or stroke. Avoid alcohol, as it raises the chance of stomach bleeding and liver problems. Tell every doctor, dentist, or surgeon that you are taking this medicine before any procedure. Avoid starting new medicines, especially painkillers like ibuprofen or naproxen, without checking with your doctor. Report any unusual bleeding, bruising, muscle pain, or dark urine promptly. Keep all follow-up appointments for blood tests and heart checks.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of bleeding, kidney problems, and muscle side effects. The dose may need adjustment based on kidney and liver function. Regular monitoring of blood counts, renal function, and liver enzymes is especially important in this age group.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy or when planning pregnancy. If you are trying to conceive, consult your doctor to review your medicines and switch to safer alternatives if needed. Use effective contraception while on this medicine unless your doctor advises otherwise.
🏥 Post-Surgery Considerations
This medicine increases bleeding risk and should be stopped before surgery as advised by your surgeon, usually 5-7 days before. It should only be restarted after your surgeon confirms it is safe. Never stop or restart on your own.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental work, including extractions or gum surgery. Your dentist may consult your doctor about temporarily stopping the medicine or taking extra precautions to control bleeding.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Regular exercise is encouraged, but avoid contact sports or activities with a high risk of injury or bleeding while on this medicine. If you experience muscle pain, weakness, or unusual tiredness during exercise, stop and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is unlikely to affect your ability to drive or operate machinery. However, if you experience dizziness, headache, or visual changes, avoid driving until you feel better. Inform your employer if your job involves a high risk of injury, as the medicine increases bleeding risk.
🛑 When to Stop This Medicine
Do not stop this medicine on your own. Your doctor may consider stopping or changing it if you develop serious side effects such as severe bleeding, liver injury, or muscle damage, or if your risk profile changes. Always consult your doctor before stopping.
📅 Long-Term Use Effects
Long-term use of this medicine significantly reduces the risk of heart attack, stroke, and cardiovascular death in high-risk patients. However, it requires regular monitoring of blood counts, liver function, kidney function, and lipid levels. Prolonged use may increase the risk of gastrointestinal bleeding, muscle problems, and liver enzyme abnormalities. Your doctor will periodically assess whether the benefits still outweigh the risks and may adjust the treatment.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and smoking cessation can help manage cardiovascular risk but may not be sufficient for high-risk patients.
Evidence: Well-establishedSome patients may be managed with aspirin alone, clopidogrel alone, or a statin alone, depending on their risk profile.
Evidence: Well-establishedTicagrelor or prasugrel may be used instead of clopidogrel in certain patients.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions with this medicine. However, inform your healthcare provider before any vaccination, especially if you are due for surgery or have a bleeding disorder. Flu and pneumonia vaccines are generally recommended for heart patients.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid loss or temperature extremes. If crossing time zones, continue taking your dose at the same local time each day; if unsure, consult your doctor. Store away from direct sunlight and moisture. Check customs regulations for controlled medicines, though this is not a controlled substance in most countries. Always carry enough supply for your entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The antiplatelet effect starts within hours, but the full protective benefit and cholesterol lowering take several weeks. Continue taking it as prescribed.
A: No. Stopping suddenly can increase the risk of heart attack or stroke. Always consult your doctor before making any changes.
A: If you remember within 12 hours, take it. If more than 12 hours have passed, skip it and continue your regular schedule. Do not double dose.
A: Yes, taking it with food is recommended to reduce stomach upset.
A: This medicine is generally avoided during pregnancy. Consult your doctor immediately if you are pregnant or planning pregnancy.
🤔 Common Patient Concerns
🔄 Substitutes for davaindia aspirin+rosuvastatin+clopidogrel 150mg/20mg/75mg capsule
View AllAlternative brands with exact same active ingredient:
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Rozanex AS 20mg/150mg TabletVidakem Lifesciences Pvt Ltd ₹57.49 12.7% COSTLIER
-
razel-a 150 tabletGlenmark Pharmaceuticals Ltd ₹62.00 21.6% COSTLIER
-
rozavel a forte 150 capsuleSun Pharmaceutical Industries Ltd ₹87.46 71.5% COSTLIER
-
roseday-a 20 forte capsuleUSV Ltd ₹87.65 71.9% COSTLIER
-
rosumac asp forte 20mg/150mg capsuleMacleods Pharmaceuticals Pvt Ltd ₹90.94 78.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be stopped once cholesterol is normal.
Fact: Cholesterol may be normal because of the medicine. Stopping it can raise cholesterol again and increase heart risk. Always consult your doctor before stopping. - Myth: This medicine can be taken for any chest pain.
Fact: This medicine is for long-term prevention, not for sudden chest pain. Sudden chest pain needs emergency evaluation. - Myth: Taking this medicine means I can eat anything.
Fact: A heart-healthy diet and lifestyle are still essential for the best results. - Myth: This medicine is safe to take with painkillers like ibuprofen.
Fact: Ibuprofen and similar painkillers increase bleeding risk and can reduce the protective effect of aspirin. Always check with your doctor.
🔄 Alternative Options
Generic Alternatives
- Aspirin 150 mg + Rosuvastatin 20 mg + Clopidogrel 75 mg capsule (various manufacturers)