cyclox 500mg capsule - Cloxacillin (500mg) medicine

cyclox 500mg capsule

4.6 (9 reviews)
๐Ÿญ Oyster Labs Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is cyclox 500mg capsule used for?

Bioclox 250mg Capsule (Cloxacillin) is used to treat ANTI INFECTIVES. It contains Cloxacillin (500mg), which Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Cloxacillin
  • Manufacturer: Oyster Labs Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š cyclox 500mg capsule Uses & Benefits

Treatment of infections caused by penicillinase-producing staphylococci, including skin and soft tissue infections, respiratory tract infections, osteomyelitis, and septicemia.

Off-label uses: Prophylaxis in dental procedures, Treatment of anthrax (in combination)

๐Ÿ“‹ Drug Information

Generic Name(s)Cloxacillin
Brand NameBioclox 250mg Capsule
ManufacturerOyster Labs Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassCell wall active agent- Penicillinase resistant Penicillin
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC) in a dry place; protect from light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from the gastrointestinal tract; absorption is enhanced when taken on an empty stomach.
DistributionDistributes widely into body tissues and fluids, including bone, pleural fluid, and synovial fluid. Crosses the placenta and enters breast milk.
Protein BindingApproximately 93-95% bound to plasma proteins, mainly albumin.
MetabolismPartially metabolized in the liver to active and inactive metabolites.
Half-Life0.5-1 hour in adults; prolonged in neonates and patients with renal impairment.
ExcretionPrimarily excreted unchanged in urine via renal tubular secretion; also eliminated in bile.
BioavailabilityOral bioavailability is about 50-70% due to first-pass metabolism.
Onset of Action1-2 hours after oral administration.
Peak Plasma Time1-2 hours after oral dose.
Duration of Action4-6 hours.

How It Works

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), inhibiting transpeptidase activity, and activating autolytic enzymes.

Mechanism Steps

1Cloxacillin binds to penicillin-binding proteins (PBPs) on bacterial cell wall.
2Inhibits transpeptidase enzyme, preventing cross-linking of peptidoglycan chains.
3Activates autolytic enzymes (murein hydrolases) that degrade the cell wall.

๐Ÿ’ก How to Take cyclox 500mg capsule

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of cyclox 500mg capsule

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Rash
  • Urticaria

๐Ÿšจ Serious Side Effects

  • Anaphylaxis
  • Stevens-Johnson syndrome
  • Clostridium difficile colitis
  • Interstitial nephritis

โš ๏ธ Rare Side Effects

  • Hemolytic anemia
  • Agranulocytosis
  • Hepatitis
  • Seizures (high doses)

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Methotrexate Major Increased methotrexate toxicity
Warfarin Major Increased bleeding risk
Probenecid Major Decreased renal excretion of cloxacillin
Oral contraceptives Moderate Reduced contraceptive efficacy
Cyclosporine Moderate Decreased cyclosporine levels
Tetracyclines Moderate Antagonistic effect
Allopurinol Minor Increased risk of skin rash
Chloramphenicol Minor Antagonistic effect
Neomycin Minor Decreased absorption of cloxacillin

๐Ÿšจ Major Interactions

  • Methotrexate
  • Warfarin
  • Probenecid

โšก Moderate Interactions

  • Oral contraceptives
  • Cyclosporine
  • Tetracyclines

โ„น๏ธ Minor Interactions

  • Allopurinol
  • Chloramphenicol
  • Neomycin

๐Ÿฝ๏ธ Food Interactions

Food may decrease absorption; take on an empty stomach.

๐Ÿท Alcohol Interaction

No known interaction; moderate consumption unlikely to cause issues.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to penicillins; history of allergic reaction to cephalosporins (cross-sensitivity).

๐Ÿ“Š Monitoring Parameters

Renal function, hepatic function, CBC, signs of hypersensitivity, and bacterial susceptibility.

๐Ÿคฑ Lactation Safety

Excreted in breast milk in small amounts; generally considered compatible with breastfeeding.

๐Ÿ’Š Overdose Management

Supportive care; hemodialysis may be effective in severe cases.

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose and resume regular schedule. Do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for cyclox 500mg capsule

View All

Alternative brands with exact same active ingredient (Cloxacillin (500mg)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Regular Customer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Regular Customer Jul 10, 2026

Effective and reliable. Worked as expected.

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

Happy Patient Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Happy Patient Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

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