cortilate n ointment - Neomycin (NA) medicine

cortilate n ointment

4.8 (13 reviews)
๐Ÿญ Micro Labs Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is cortilate n ointment used for?

Cortilate N Ointment (Neomycin) is used to treat DERMA. It contains Neomycin (NA), which Neomycin binds to 30S ribosomal subunit, inhibiting bacterial protein synthesis.. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Neomycin
  • Manufacturer: Micro Labs Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š cortilate n ointment Uses & Benefits

Treatment of superficial bacterial skin infections; prophylaxis in minor cuts and abrasions.

Off-label uses: Treatment of infected eczema, Prophylaxis in minor burns

๐Ÿ“‹ Drug Information

Generic Name(s)Neomycin
Brand NameCortilate N Ointment
ManufacturerMicro Labs Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassAminoglycosides
Route of AdministrationTopical
StorageStore at room temperature (20-25ยฐC); keep tightly closed.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMinimal systemic absorption when applied topically to intact skin; absorption increases through broken or abraded skin.
DistributionDistributes primarily locally; systemic distribution negligible with topical use.
Protein BindingNot applicable (topical); if absorbed, neomycin is weakly protein-bound.
MetabolismNot metabolized significantly; if absorbed, excreted unchanged.
Half-LifeNot applicable topically; systemic half-life ~2-3 hours if absorbed.
ExcretionRenal excretion of absorbed fraction unchanged.
BioavailabilityNegligible via topical route.
Onset of ActionWithin 24-48 hours for antibacterial effect.
Peak Plasma TimeNot applicable topically.
Duration of ActionDuration depends on application frequency; typically 6-8 hours.

How It Works

Neomycin binds to 30S ribosomal subunit, inhibiting bacterial protein synthesis.

Mechanism Steps

1Neomycin enters bacterial cell via passive diffusion
2Binds to 30S ribosomal subunit
3Causes misreading of mRNA

๐Ÿ’ก How to Take cortilate n ointment

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of cortilate n ointment

โœ… Common Side Effects

  • Skin irritation
  • Redness
  • Itching
  • Dryness

๐Ÿšจ Serious Side Effects

  • Allergic contact dermatitis
  • Ototoxicity (if applied to perforated eardrum)
  • Nephrotoxicity (with prolonged use on large areas)

โš ๏ธ Rare Side Effects

  • Superinfection
  • Anaphylaxis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Aminoglycosides (systemic) Major Increased risk of nephrotoxicity and ototoxicity
Neuromuscular blocking agents Major Enhanced neuromuscular blockade
Loop diuretics Major Increased ototoxicity risk
Other nephrotoxic drugs Moderate Additive nephrotoxicity
Other ototoxic drugs Moderate Additive ototoxicity

๐Ÿšจ Major Interactions

  • Aminoglycosides (systemic)
  • Neuromuscular blocking agents
  • Loop diuretics

โšก Moderate Interactions

  • Other nephrotoxic drugs
  • Other ototoxic drugs

โ„น๏ธ Minor Interactions

  • Topical corticosteroids (additive effects)

๐Ÿท Alcohol Interaction

No known interaction.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to neomycin or any component; perforated eardrum (if used in ear); large areas of broken skin.

๐Ÿ“Š Monitoring Parameters

Monitor for signs of superinfection, allergic reaction, or nephrotoxicity if used on large wounds.

๐Ÿคฑ Lactation Safety

Caution; minimal systemic absorption but avoid prolonged use on large areas.

๐Ÿ’Š Overdose Management

Topical overdose unlikely; if ingested, supportive care; monitor renal function.

โฐ Missed Dose

Apply as soon as remembered; skip if almost time for next dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for cortilate n ointment

View All

Alternative brands with exact same active ingredient (Neomycin (NA)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Happy Patient Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Happy Patient Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Regular Customer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Happy Patient Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Regular Customer Jul 10, 2026

Effective and reliable. Worked as expected.

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