cobeta 0.05% lotion - Uses, Price, Side Effects & Substitutes
What is cobeta 0.05% lotion used for?
Abetanate Cream (Clobetasol) is used to treat DERMA. It contains Clobetasol (0.05% w/v), which Binds to glucocorticoid receptors, modulating gene expression to produce anti-in. Always consult your doctor before use. Take as prescribed.
- Generic Name: Clobetasol
- Manufacturer: Oziel Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ cobeta 0.05% lotion Uses & Benefits
Treatment of corticosteroid-responsive dermatoses such as psoriasis, eczema, dermatitis, and lichen planus.
Off-label uses: Alopecia areata, Vitiligo, Lichen sclerosus
๐ Drug Information
| Generic Name(s) | Clobetasol |
| Brand Name | Abetanate Cream |
| Manufacturer | Oziel Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | Glucocorticoids |
| Route of Administration | Topical |
| Storage | Store at room temperature 20-25ยฐC (68-77ยฐF); keep tightly closed. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Binds to glucocorticoid receptors, modulating gene expression to produce anti-inflammatory, antipruritic, and vasoconstrictive effects.
Mechanism Steps
๐ก How to Take cobeta 0.05% lotion
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of cobeta 0.05% lotion
โ Common Side Effects
- Burning
- itching
- irritation
- dryness
- folliculitis
- hypertrichosis
- acneiform eruptions
- hypopigmentation
- perioral dermatitis
- allergic contact dermatitis
- maceration
- secondary infection
- skin atrophy
- striae
- miliaria
๐จ Serious Side Effects
- HPA axis suppression
- Cushing's syndrome
- hyperglycemia
- glucosuria
- adrenal insufficiency
- growth retardation in children
- intracranial hypertension
- cataracts
- glaucoma
โ ๏ธ Rare Side Effects
- Kaposi's sarcoma
- osteonecrosis
- pancreatitis
- psychiatric disturbances
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Ketoconazole | Major | Increased systemic corticosteroid levels |
| Aspirin | Moderate | Increased risk of gastrointestinal bleeding |
| Live vaccines | Minor | Reduced vaccine efficacy or increased infection risk |
๐จ Major Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
- Anticoagulants (e.g., warfarin)
โก Moderate Interactions
- NSAIDs
- Aspirin
- Diuretics
โน๏ธ Minor Interactions
- Vaccines (live attenuated)
- Antidiabetic agents
๐ฝ๏ธ Food Interactions
No significant food interactions
๐ท Alcohol Interaction
No significant interaction
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to clobetasol or any component; untreated bacterial, fungal, or viral skin infections; rosacea; perioral dermatitis; acne vulgaris.
๐ Monitoring Parameters
Monitor for skin atrophy, signs of systemic absorption (e.g., HPA axis suppression), and local adverse reactions.
๐คฑ Lactation Safety
Use with caution; avoid application to breast area if nursing.
๐ Overdose Management
Topical overdose unlikely; excessive use may cause systemic effects. Discontinue use and treat symptomatically.
โฐ Missed Dose
Apply as soon as remembered; if near next dose, skip missed dose and resume regular schedule. Do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for cobeta 0.05% lotion
View AllAlternative brands with exact same active ingredient (Clobetasol (0.05% w/v)):
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cvate solutionOmega Remedies Pvt Ltd โน35.86 49% CHEAPER
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cortisol lotionPsycormedies โน45.00 36% CHEAPER
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Cbs L LotionWest-Coast Pharmaceutical Works Ltd โน55.35 21.3% CHEAPER
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clopan lotionPanzer Pharmaceuticals Pvt Ltd โน56.25 20% CHEAPER
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clobet lotionMepro Pharmaceuticals โน58.59 16.7% CHEAPER
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dermaquit lotionQuantum Formulations โน60.00 14.7% CHEAPER
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closol lotionP and P Dermaceuticals Pvt Ltd โน66.56 5.3% CHEAPER
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gzlsalic lotionGedzrlvin Pharmaceuticals Pvt Ltd โน68.34 2.8% CHEAPER
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gzlsalic ointmentGedzrlvin Pharmaceuticals Pvt Ltd โน68.34 2.8% CHEAPER
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clobisol 0.05% lotionVelite Pharmaceuticals โน70.00 0.4% CHEAPER
Medical Note: Always consult your doctor before switching medications.