coaltoz-kz shampoo - Ketoconazole (2% w/v) + Salicylic Acid (2% w/v) medicine

Acvaketo S Shampoo: Complete Guide to Uses, Side Effects, and Safety

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🏭 Cytoz Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for dandruff and seborrheic dermatitis.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction (swelling of face, lips, throat, difficulty breathing)
  • Severe skin irritation or blistering
  • Signs of infection (increased redness, warmth, pus)
  • Hair loss that is sudden or severe
  • No improvement after 4 weeks of use
  • Worsening of condition

If experiencing severe symptoms, call emergency services immediately.

What is coaltoz-kz shampoo used for?

This medicine is a medicated shampoo containing ketoconazole 2% and salicylic acid 2%. It treats dandruff and seborrheic dermatitis by killing fungi and removing scales. Use twice weekly for 2-4 weeks, then once weekly. Avoid contact with eyes.

  • Generic Name: Ketoconazole + Salicylic Acid
  • Manufacturer: Cytoz Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 coaltoz-kz shampoo के बारे में (Hindi Summary)

उपयोग: यह दवा एक टॉपिकल शैम्पू है जिसमें कीटोकोनाज़ोल 2% और सैलिसिलिक एसिड 2% होता है। यह डैंड्रफ और सेबोरहाइक डर्मेटाइटिस के इलाज के लिए उपयोग किया जाता है। यह स्कैल्प पर फंगस को मारता है और पपड़ी को हटाता है।

साइड इफेक्ट्स: आम दुष्प्रभावों में स्कैल्प में जलन, सूखापन, खुजली या हल्की जलन शामिल है। कभी-कभी एलर्जी प्रतिक्रिया हो सकती है। यदि कोई गंभीर दुष्प्रभाव हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: केवल बाहरी उपयोग के लिए। आंखों, नाक, मुंह और श्लेष्मा झिल्ली से बचें। टूटी त्वचा पर न लगाएं। 12 वर्ष से कम बच्चों में डॉक्टर की सलाह के बिना उपयोग न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से परामर्श करें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 coaltoz-kz shampoo Uses & Benefits

[{"condition":"Dandruff","description":"Reduces flaking and itching associated with dandruff by targeting Malassezia yeast and removing scales.","evidence":"Well-established"},{"condition":"Seborrheic dermatitis of the scalp","description":"Helps control redness, scaling, and itching in seborrheic dermatitis.","evidence":"Well-established"},{"condition":"Tinea versicolor (when applied to affected areas)","description":"May be used off-label for tinea versicolor on the body, but this shampoo is primarily for scalp.","evidence":"Limited"}]

Off-label uses: [{"condition":"Seborrheic dermatitis of the face or chest","description":"Sometimes used off-label for seborrheic dermatitis in other areas, but should be used only under medical supervision.","evidence":"Limited"}]

Primary treatment for: Dandruff and seborrheic dermatitis of the scalp

Also treats: Tinea versicolor (off-label)

📋 Drug Information

Generic Name(s)Ketoconazole + Salicylic Acid
Brand NameAcvaketo S Shampoo
ManufacturerCytoz Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassAntifungal + Keratolytic
Route of AdministrationTopical
StorageStore at room temperature (15-30°C). Protect from direct sunlight. Keep the container tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Use this medicine twice weekly for the first 2-4 weeks, then once weekly for maintenance.
2
Leave the shampoo on the scalp for at least 3-5 minutes before rinsing for maximum effect.
3
Avoid contact with eyes; if contact occurs, rinse thoroughly with water.
4
Do not use on broken or inflamed skin.
5
If symptoms do not improve after 4 weeks, consult a doctor.
6
Use a conditioner after shampooing to prevent hair dryness.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Scalp flaking
This medicine is commonly prescribed for this.
Likely Use
✅
Scalp itching
This medicine helps relieve itching.
Likely Use
✅
Redness on scalp
This medicine can reduce redness associated with seborrheic dermatitis.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionKetoconazole is minimally absorbed through intact skin when applied topically. Systemic absorption is negligible. Salicylic acid can be absorbed through the skin, especially if applied to large areas or broken skin, but systemic effects are unlikely with normal shampoo use.
DistributionNot established from the available information.
Protein BindingNot established from the available information.
MetabolismNot established from the available information.
Half-LifeNot established from the available information.
ExcretionNot established from the available information.
BioavailabilityNot established from the available information.
Onset of ActionImprovement in scaling and itching may be noticed within a few days to weeks of regular use.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe effect lasts between applications; regular use is needed to control symptoms.

How It Works

Ketoconazole inhibits the fungal enzyme cytochrome P450 14α-demethylase, blocking the conversion of lanosterol to ergosterol, which is essential for fungal cell membrane integrity. This leads to increased membrane permeability and fungal cell death. Salicylic acid is a beta-hydroxy acid that disrupts corneocyte cohesion, softening and shedding scales, and also has mild anti-inflammatory and antimicrobial properties.

Mechanism Steps

1
Ketoconazole uptake: Ketoconazole penetrates the fungal cell membrane and enters the fungal cell.
2
Inhibition of ergosterol synthesis: Ketoconazole inhibits 14α-demethylase, blocking ergosterol production, a key component of the fungal cell membrane.
3
Fungal cell membrane disruption: Without ergosterol, the fungal membrane becomes permeable, leading to leakage of cellular contents and cell death.
4
Salicylic acid keratolysis: Salicylic acid loosens the bonds between corneocytes, promoting shedding of scales and reducing flaking.
5
Reduction of scaling and itching: The combined actions reduce fungal burden and scalp scaling, alleviating itching and flaking.

💡 How to Take coaltoz-kz shampoo

Strength: Shampoo containing ketoconazole 2% w/v and salicylic acid 2% w/v.

1Wet your hair and scalp thoroughly with water.
2Apply a sufficient amount of the shampoo to create a lather.
3Massage gently into the scalp, avoiding the eyes.
4Leave the lather on for 3-5 minutes.
5Rinse thoroughly with water.
6Use as directed by your doctor, usually twice weekly for the first few weeks, then once weekly.

Dosage Information

Adult DosageWet hair and scalp thoroughly. Apply a sufficient amount to lather, massage into the scalp, and leave on for 3-5 minutes. Rinse thoroughly. Use twice weekly for 2-4 weeks, then once weekly or as directed by a doctor. Dose must be individualized by a qualified clinician based on indication, age, and response.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo specific dose adjustment is required for elderly patients. Use as directed by a doctor.
Renal ImpairmentNo dose adjustment is required for renal impairment when used topically.
Hepatic ImpairmentNo dose adjustment is required for hepatic impairment when used topically.
Maximum Daily DoseNot applicable for topical shampoo. Use as directed.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Apply the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of coaltoz-kz shampoo

✅ Common Side Effects

Scalp irritation (Common (1-10%))
Usually resolves with continued use. If persistent, reduce frequency or consult a doctor.
Dryness of scalp or hair (Common (1-10%))
Use a moisturizing conditioner after shampooing. If severe, consult a doctor.
Itching (Common (1-10%))
Avoid scratching. If itching worsens, consult a doctor.
Burning sensation (Uncommon (0.1-1%))
Rinse thoroughly with water. If persists, discontinue and consult a doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of face, lips, throat, difficulty breathing, or severe rash.
Severe skin irritation or blistering (Rare (<0.1%))
Discontinue use and consult a doctor immediately.

⚠️ Rare Side Effects

Hair loss or hair thinning
Consult a doctor if you notice significant hair loss.
Contact dermatitis
Discontinue use and consult a doctor.

Consult your doctor if you experience any unusual symptoms.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to ketoconazole, salicylic acid, or any component of the formulation.","Do not use on broken or inflamed skin.","Do not use in children under 12 years unless prescribed by a doctor."]

⚠️ Warnings & Precautions

["For external use only. Avoid contact with eyes, lips, and mucous membranes.","If accidental contact with eyes occurs, rinse thoroughly with water.","Do not use on large areas of the body or for prolonged periods without medical advice.","If condition worsens or does not improve after the recommended treatment period, consult a doctor.","Keep out of reach of children.","Do not use if you are pregnant or breastfeeding without consulting a doctor.","Do not use on the face or genital area unless directed by a physician."]

🤱 Lactation Safety

It is not known whether ketoconazole or salicylic acid from this shampoo passes into breast milk. Consult your doctor before use while breastfeeding. Avoid applying to the breast area to prevent infant exposure.

💊 Overdose Management

Accidental ingestion may cause nausea, vomiting, and abdominal pain. Seek immediate medical attention or contact a poison control center. Topical overdose is unlikely; if excessive application occurs, rinse thoroughly with water and consult a doctor if irritation persists.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

For external use only. Avoid contact with eyes, nose, mouth, and other mucous membranes. If accidental contact occurs, rinse thoroughly with water. Do not apply to broken or inflamed skin. Do not use on children under 12 years unless prescribed by a doctor. If you are pregnant or breastfeeding, consult your doctor before use. Keep out of reach of children. Do not use if you are allergic to any ingredient. Do not exceed the recommended frequency or duration of use. If condition worsens or does not improve after the recommended treatment period, consult a doctor. Do not use on the face or genital area unless specifically directed by a physician.

👴 Special Considerations for Elderly

💡 For Patients Above 65

No specific precautions for elderly patients. Use as directed by a doctor.

🤰 Pregnancy Planning (TTC)

Consult your doctor before use if you are planning pregnancy or are pregnant. Topical use is generally considered low risk, but medical advice is recommended.

🏥 Post-Surgery Considerations

No specific considerations for post-surgery unless directed by your doctor. Avoid applying to surgical wounds.

🦷 Dental Procedures

No specific considerations for dental procedures. This medicine is for scalp use only.

💚 Lifestyle Tips for Better Results

🏃
Wash your hair regularly with a mild shampoo to prevent buildup.
🥗
Avoid sharing combs, hats, or towels to prevent spread of infection.
😴
Manage stress as it can worsen dandruff.
💧
Eat a balanced diet rich in vitamins and minerals.
🧘
Avoid excessive use of hair styling products.

🏋️ Exercise Considerations

No specific exercise precautions are needed while using this medicine. However, avoid swimming immediately after application to prevent washing off the medicine.

🥗 Diet Recommendations

Include foods rich in zinc and B vitamins.
Stay hydrated.
Limit sugary and processed foods.

💼 Impact on Daily Work & Life

This medicine has no impact on driving or operating machinery. It may cause mild scalp irritation, but this does not affect daily activities.

🛑 When to Stop This Medicine

Stop using this medicine and consult a doctor if you experience severe irritation, allergic reaction, or if your condition worsens. Do not stop prescribed treatment without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe when used as directed. Prolonged use may lead to scalp dryness or irritation. If used for extended periods, periodic evaluation by a doctor is recommended. Do not use continuously for more than 4 weeks without medical advice.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Selenium sulfide shampoo

Another antifungal shampoo for dandruff.

Evidence: Well-established
Zinc pyrithione shampoo

Over-the-counter antifungal shampoo.

Evidence: Well-established
Coal tar shampoo

Helps reduce scaling and itching.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interaction with vaccines. Continue routine vaccinations as scheduled.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. No time zone adjustments are needed for topical use. Declare it at customs if required.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 30-year-old man with persistent dandruff
He used this shampoo twice weekly as directed. After 2 weeks, his flaking and itching reduced significantly. He continued once weekly for maintenance and saw sustained improvement.
💡 Lesson: Consistent use as directed leads to good control of dandruff.
👤 A 45-year-old woman with seborrheic dermatitis
She had redness and scaling on her scalp. Her doctor prescribed this shampoo. She used it twice weekly for a month and noticed reduced redness and scaling. She now uses it once weekly to keep symptoms away.
💡 Lesson: Regular maintenance therapy helps prevent flare-ups.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may notice improvement in flaking and itching within 1-2 weeks of regular use. Full benefits may take up to 4 weeks.

Q: Can I use this shampoo every day?

A: No, it is usually used twice weekly for 2-4 weeks, then once weekly. Using it daily may cause irritation.

Q: Is it safe for children?

A: It is not recommended for children under 12 years unless prescribed by a doctor.

Q: Can I use it during pregnancy?

A: Consult your doctor before use if you are pregnant or breastfeeding.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this shampoo long-term?
  • Will it affect my hair color?
  • Can I use it if I have psoriasis?
  • Does it interact with other hair products?
  • What if I miss a dose?
  • Can I use it during pregnancy?

🔄 Substitutes for coaltoz-kz shampoo

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Using more shampoo will cure dandruff faster.
    Fact: Using more than directed can cause irritation and dryness. Follow the recommended frequency.
  • Myth: Dandruff is caused by poor hygiene.
    Fact: Dandruff is often caused by Malassezia yeast and is not due to poor hygiene.
  • Myth: This shampoo can be used on the face.
    Fact: This shampoo is for scalp use only unless directed by a doctor.

🔄 Alternative Options

Generic Alternatives

  • Ketoconazole 2% shampoo
  • Salicylic acid 2% shampoo
  • Ketoconazole and salicylic acid shampoo

📊 Comparison with Similar Medicines

[{"medicine":"Ketoconazole 2% shampoo","active_ingredient":"Ketoconazole","primary_use":"Dandruff, seborrheic dermatitis","notes":"Antifungal only"},{"medicine":"Salicylic acid 2% shampoo","active_ingredient":"Salicylic acid","primary_use":"Dandruff, psoriasis","notes":"Keratolytic only"},{"medicine":"This medicine","active_ingredient":"Ketoconazole + Salicylic acid","primary_use":"Dandruff, seborrheic dermatitis","notes":"Combined antifungal and keratolytic action"}]

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