Candid-V 6 Tablet ER: Complete Guide to Uses, Dosage, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, or throat, or difficulty breathing
- Severe vaginal bleeding
- Pelvic pain with fever and foul-smelling discharge
- No improvement after 7 days of treatment
- Symptoms that get worse after starting the medicine
- Severe burning or pain that prevents you from inserting the tablet
- New rash or hives over the body
If experiencing severe symptoms, call emergency services immediately.
What is closupp 100mg suppository used for?
This medicine is a vaginal tablet containing clotrimazole 100 mg. It treats vaginal yeast infections by stopping fungal growth. Insert one tablet high into the vagina at bedtime for 6 to 7 days, or as directed by your doctor. Do not swallow it.
- Generic Name: Clotrimazole
- Manufacturer: Meridian Enterprises Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 closupp 100mg suppository के बारे में (Hindi Summary)
उपयोग: यह दवा योनि में होने वाले फंगल संक्रमण (कैंडिडिआसिस) के इलाज के लिए इस्तेमाल की जाती है। इसमें क्लोट्रिमाज़ोल 100 मिलीग्राम होता है, जो फंगस को बढ़ने से रोकता है। यह दवा योनि में डालने के लिए होती है, इसे मुँह से नहीं लेना चाहिए। आमतौर पर इसे रात को सोने से पहले 6 से 7 दिन तक इस्तेमाल किया जाता है। यह खुजली, जलन और असामान्य स्राव को कम करने में मदद करती है।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में योनि में हल्की जलन, खुजली या असहजता शामिल हैं। कुछ महिलाओं को स्राव बढ़ने जैसा महसूस हो सकता है। ये आमतौर पर हल्के होते हैं और कुछ दिनों में ठीक हो जाते हैं। गंभीर एलर्जी प्रतिक्रिया जैसे चेहरे या गले में सूजन, सांस लेने में कठिनाई बहुत कम होती है, लेकिन अगर ऐसा हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा का इस्तेमाल डॉक्टर की सलाह के अनुसार ही करें। इस्तेमाल से पहले और बाद में हाथ धोएँ। टैबलेट को एप्लीकेटर की मदद से योनि में गहराई तक डालें, बेहतर होगा कि रात को सोने से पहले डालें। माहवारी के दौरान इसका इस्तेमाल न करें, जब तक डॉक्टर मना न करें। इलाज के दौरान संभोग से बचें। टैम्पोन या अन्य योनि उत्पादों का इस्तेमाल न करें। अगर 7 दिन में सुधार न हो तो डॉक्टर से संपर्क करें।
💊 closupp 100mg suppository Uses & Benefits
[{"condition":"Vulvovaginal candidiasis (vaginal yeast infection)","description":"Treats vaginal yeast infections caused by Candida albicans and other Candida species, relieving itching, burning, and abnormal discharge.","evidence":"Well-established"},{"condition":"Prevention of recurrent vaginal yeast infections","description":"May be used intermittently or as maintenance therapy in women with frequent recurrences, as directed by a clinician.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Oral thrush (oropharyngeal candidiasis)","description":"Sometimes compounded into a mouth rinse or lozenge for oral fungal infections, but this is not the intended use of the vaginal tablet.","evidence":"Limited"}]
Primary treatment for: Vulvovaginal candidiasis
Also treats: Recurrent vaginal yeast infections, Vaginal candidiasis in pregnancy
📋 Drug Information
| Generic Name(s) | Clotrimazole |
| Brand Name | Af -c dusting powder |
| Manufacturer | Meridian Enterprises Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | Fungal ergosterol synthesis inhibitor |
| Route of Administration | Vaginal (topical) |
| Storage | Store at room temperature between 15°C and 30°C. Keep in the original packaging to protect from light and moisture. Do not refrigerate. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the pack. Do not use after the expiry date. |
| WHO Guideline | The World Health Organization includes clotrimazole in its list of essential medicines for the treatment of vaginal candidiasis. It is recommended as a topical azole for uncomplicated cases. |
| ICMR Guideline | The Indian Council of Medical Research recognizes topical azoles such as clotrimazole as first-line treatment for uncomplicated vulvovaginal candidiasis. It advises confirming the diagnosis and treating for the full duration. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Clotrimazole works by inhibiting the fungal enzyme lanosterol 14-alpha-demethylase, which is needed to make ergosterol, a key component of the fungal cell membrane. Without enough ergosterol, the fungal cell membrane becomes weak and leaky. This damages the fungus and stops it from growing. Clotrimazole is mainly fungistatic at lower concentrations and can be fungicidal at higher concentrations. It has activity against many Candida species, including Candida albicans.
Mechanism Steps
💡 How to Take closupp 100mg suppository
Strength: Vaginal tablet, 100 mg
Dosage Information
| Adult Dosage | For vaginal yeast infection, the usual adult dose is one 100 mg vaginal tablet inserted high into the vagina once daily at bedtime for 6 to 7 days. Some clinicians may recommend a different schedule. Dose must be individualized by a qualified clinician based on the severity of infection, response to treatment, and whether you are pregnant. Always follow your doctor's instructions. Do not use more or less than prescribed. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dose adjustment is needed for elderly women. The same adult dose can be used, but a doctor should evaluate for other causes of vaginal symptoms, as dryness and other conditions are more common with age. |
| Renal Impairment | No dose adjustment is needed for kidney disease because systemic absorption is minimal. However, tell your doctor if you have kidney problems. |
| Hepatic Impairment | No dose adjustment is needed for liver disease because systemic absorption is minimal. However, tell your doctor if you have liver problems. |
| Maximum Daily Dose | One 100 mg vaginal tablet per day, or as prescribed by your doctor. Do not exceed the recommended dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of closupp 100mg suppository
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Tacrolimus | Major | |
| Sirolimus | Major | |
| Warfarin | Moderate | |
| Simvastatin | Moderate | |
| Atorvastatin | Moderate | |
| Oral contraceptives | Minor | |
| Oral antibiotics | Minor |
🚨 Major Interactions
- Tacrolimus (systemic)
- Sirolimus (systemic)
⚡ Moderate Interactions
- Warfarin
- Statins (e.g., simvastatin, atorvastatin)
🍷 Alcohol Interaction
Alcohol is not expected to interact with this medicine because systemic absorption is minimal. However, alcohol can worsen dehydration and irritation, so it is best to drink in moderation while you are recovering from a vaginal infection.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy or hypersensitivity to clotrimazole or any other azole antifungal","Use in children under 12 years without medical advice","Use in anyone who has not been evaluated for the cause of vaginal symptoms","Do not use if you have a fever, pelvic pain, or foul-smelling discharge without seeing a doctor first"]
⚠️ Warnings & Precautions
["For vaginal use only. Do not take by mouth.","Wash your hands before and after inserting the tablet.","Use the applicator provided to place the tablet high in the vagina.","Avoid vaginal intercourse during treatment.","Do not use tampons or other vaginal products while using this medicine.","If you are pregnant or breastfeeding, consult your doctor before use.","If symptoms do not improve within 7 days, or if they worsen, contact your doctor.","Keep out of reach of children.","Do not use this medicine if the tablet is discolored or damaged.","Do not share this medicine with others."]
🤱 Lactation Safety
Clotrimazole is unlikely to pass into breast milk in significant amounts after vaginal use. It is generally considered safe during breastfeeding. However, consult your doctor before use, and avoid applying the medicine to the breast area.
💊 Overdose Management
Overdose with this medicine is unlikely because it is used vaginally. If someone accidentally swallows the tablet, contact a doctor or poison control center immediately. Symptoms of swallowing clotrimazole may include nausea, vomiting, and abdominal pain. Treatment is supportive and based on symptoms.
⏰ Missed Dose
If you miss a dose, insert it as soon as you remember, unless it is almost time for your next dose. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not insert two tablets at once to make up for a missed dose.
Additional Safety Advice
Use this medicine only as directed by your doctor. Wash your hands before and after inserting the tablet. Insert the tablet high into the vagina using the applicator provided, preferably at bedtime so it stays in place. Do not use this medicine during your menstrual period unless your doctor says it is okay. Avoid vaginal intercourse while using this medicine, as it may reduce effectiveness and irritate the area. Do not use tampons or other vaginal products during treatment. If you are pregnant or breastfeeding, tell your doctor before using this medicine. Keep this medicine out of reach of children. Do not share this medicine with anyone else. If symptoms do not improve within 7 days, or if they get worse, contact your doctor.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly women may be more prone to vaginal dryness and irritation. Use the applicator gently and consider using a water-based lubricant if needed. If you have other health conditions or take multiple medicines, tell your doctor before using this medicine. Vaginal yeast infections in older women may be a sign of diabetes or other underlying conditions, so evaluation is important.
🤰 Pregnancy Planning (TTC)
If you are trying to conceive and have a vaginal yeast infection, this medicine can be used as directed by your doctor. It is considered safe in pregnancy. However, if you are undergoing fertility treatment or have any concerns, consult your doctor before use.
🏥 Post-Surgery Considerations
If you have recently had pelvic or vaginal surgery, consult your doctor before using this medicine. Inserting a vaginal tablet may not be advisable immediately after certain procedures. Follow your surgeon's instructions regarding vaginal products.
🦷 Dental Procedures
This medicine is used vaginally and does not affect dental procedures. You can continue using it as prescribed. If you are scheduled for dental work, inform your dentist about all medicines you are taking.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
You can continue your normal exercise routine while using this medicine. However, if you experience discomfort, avoid activities that cause friction or pressure on the genital area, such as cycling or prolonged sitting on hard surfaces. Shower and change into dry clothes after exercising to prevent moisture buildup.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is used vaginally at bedtime and should not affect your ability to work or drive. You can continue your daily activities as usual. If you experience any discomfort or side effects, adjust your schedule as needed. There is no need to take time off work unless your doctor advises otherwise.
🛑 When to Stop This Medicine
Stop using this medicine and contact your doctor if you experience a severe allergic reaction, severe irritation, or if your symptoms do not improve within 7 days. Do not stop the course early just because you feel better, as this can lead to recurrence. Always consult your doctor before stopping if you are unsure.
📅 Long-Term Use Effects
Long-term use of this medicine is not usually needed for uncomplicated vaginal yeast infections. If you have recurrent infections, your doctor may recommend a longer maintenance course. Prolonged use can rarely lead to local irritation or allergic reactions. It is important to have recurrent symptoms evaluated to rule out other causes such as diabetes or other infections. Do not use this medicine continuously without medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A single oral dose may be used for uncomplicated yeast infections, but requires a prescription.
Evidence: Well-establishedSometimes used for recurrent yeast infections, but must be compounded and used under medical supervision.
Evidence: ModerateMay help restore healthy vaginal flora and reduce recurrence, but evidence is mixed.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. You can receive vaccinations while using this medicine. If you have any concerns, discuss them with your doctor.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate
✅ DO
Keep in the original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription label. Keep a copy of your prescription with you, especially when traveling internationally. Store it in your carry-on luggage to avoid extreme temperatures in checked baggage. If you are traveling across time zones, continue taking your doses at the same interval as prescribed; for a once-daily bedtime dose, you can adjust to the new bedtime. Check customs rules for carrying medicines in your destination country. Keep the medicine away from direct sunlight and heat.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Most women notice relief from itching and burning within 1 to 3 days. However, you must complete the full course, usually 6 to 7 days, to clear the infection completely.
A: It is best to avoid using this medicine during your period unless your doctor says it is okay. Menstrual flow can wash the tablet out and reduce its effectiveness.
A: Vaginal clotrimazole is generally considered safe during pregnancy when used as directed by a doctor. However, always consult your doctor before using any medicine during pregnancy.
A: It is best to avoid vaginal intercourse during treatment. Sex can irritate the vagina, reduce the effectiveness of the medicine, and increase the risk of reinfection.
A: If you remember within 12 hours, insert the missed dose. If more than 12 hours have passed, skip it and continue with your next scheduled dose. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for closupp 100mg suppository
View AllAlternative brands with exact same active ingredient:
-
gogynax 100mg tabletShalina Laboratories Pvt Ltd ₹12.00 55% CHEAPER
-
lotril vg 100mg pessariesGufic Bioscience Ltd ₹13.22 50.4% CHEAPER
-
myconorm v 6 tablet vtPsychotropics India Ltd ₹15.23 42.9% CHEAPER
-
ctm v 100mg pessariesBDH Industries Ltd ₹16.99 36.2% CHEAPER
-
canazole vg 100mg tablet vtLupin Ltd ₹18.75 29.6% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken by mouth for oral thrush.
Fact: This medicine is a vaginal tablet and must not be swallowed. Oral thrush requires a different formulation. - Myth: You can stop using this medicine as soon as symptoms go away.
Fact: You must complete the full course to prevent the infection from coming back. - Myth: This medicine also treats bacterial vaginosis.
Fact: This medicine only treats fungal infections. Bacterial vaginosis needs antibiotics. - Myth: Using this medicine will protect you from sexually transmitted infections.
Fact: This medicine does not protect against STIs. Practice safe sex.
🔄 Alternative Options
Generic Alternatives
- Clotrimazole vaginal tablet
- Clotrimazole vaginal cream
Brand Alternatives
- Candid-V 6 Tablet ER