clopan g cream
What is clopan g cream used for?
A to Z Cream (Clobetasol + Neomycin) is used to treat DERMA. It contains Clobetasol (0.05% w/w) + Neomycin (0.5% w/w), which Clobetasol: Binds to glucocorticoid receptors, inducing anti-inflammatory protei. Always consult your doctor before use. Take as prescribed.
- Generic Name: Clobetasol + Neomycin
- Manufacturer: Panzer Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ clopan g cream Uses & Benefits
Inflammatory dermatoses with secondary bacterial infection, eczema, psoriasis, contact dermatitis.
Off-label uses: Lichen planus, Discoid lupus erythematosus
๐ Drug Information
| Generic Name(s) | Clobetasol + Neomycin |
| Brand Name | A to Z Cream |
| Manufacturer | Panzer Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | Corticosteroid + Antibiotic |
| Route of Administration | Topical |
| Storage | Store at room temperature (20-25ยฐC); keep tightly closed. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Clobetasol: Binds to glucocorticoid receptors, inducing anti-inflammatory proteins and suppressing inflammatory mediators. Neomycin: Binds to bacterial 30S ribosomal subunit, inhibiting protein synthesis.
Mechanism Steps
๐ก How to Take clopan g cream
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of clopan g cream
โ Common Side Effects
- Burning
- itching
- irritation
- dryness
- folliculitis
๐จ Serious Side Effects
- Adrenal suppression
- Cushing's syndrome
- Ototoxicity
- Nephrotoxicity
โ ๏ธ Rare Side Effects
- Allergic contact dermatitis
- Skin atrophy
- Hypopigmentation
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Moderate | Possible enhanced anticoagulant effect with systemic absorption. |
| CYP3A4 inhibitors (e.g., ketoconazole) | Moderate | Increased systemic levels of clobetasol. |
| Aminoglycosides (systemic) | Major | Additive nephrotoxicity and ototoxicity. |
๐จ Major Interactions
- Aminoglycosides (systemic)
- Ototoxic drugs
- Nephrotoxic drugs
โก Moderate Interactions
- CYP3A4 inhibitors
- Anticoagulants
โน๏ธ Minor Interactions
- Other topical corticosteroids
๐ฝ๏ธ Food Interactions
None known
๐ท Alcohol Interaction
No known interaction.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to components, viral skin infections, fungal infections, untreated bacterial infections.
๐ Monitoring Parameters
Skin improvement, signs of infection, adrenal suppression with prolonged use.
๐คฑ Lactation Safety
Use with caution; avoid application to breast area.
๐ Overdose Management
Topical overdose unlikely; if ingested, symptomatic treatment.
โฐ Missed Dose
Apply as soon as remembered; skip if almost time for next dose.
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Effective and reliable. Worked as expected.
Effective and reliable. Worked as expected.
This medicine was effective for me. I followed the doctor's advice.
Found this to be a helpful product. Good results.
Good quality medicine. Satisfied with the outcome.