Candid-CL Vaginal Suppository: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction: swelling of face, lips, throat, difficulty breathing.
- Severe watery diarrhea or bloody stools, which may indicate a serious intestinal infection.
- High fever with chills and severe abdominal pain.
- Blistering or peeling skin, sores in the mouth or eyes.
- Persistent vaginal bleeding or severe pain not relieved by the medicine.
- Symptoms worsening after starting the medicine.
If experiencing severe symptoms, call emergency services immediately.
What is cloclin 100mg/200mg vaginal capsule used for?
This medicine is a vaginal suppository containing clindamycin (an antibiotic) and clotrimazole (an antifungal). It is used to treat mixed vaginal infections caused by both bacteria and fungi. It is inserted into the vagina once daily at bedtime for 7 days.
- Generic Name: Clindamycin + Clotrimazole
- Manufacturer: Voizmed Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cloclin 100mg/200mg vaginal capsule के बारे में (Hindi Summary)
उपयोग: यह दवा एक योनि सपोजिटरी है जिसमें क्लिंडामाइसिन (एंटीबायोटिक) और क्लोट्रिमाज़ोल (एंटीफंगल) शामिल हैं। इसका उपयोग योनि में बैक्टीरिया और फंगस दोनों के कारण होने वाले मिश्रित संक्रमण के इलाज के लिए किया जाता है। यह योनि में डाली जाती है और रात में सोने से पहले एक बार लगाई जाती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में योनि में जलन, खुजली, या असुविधा शामिल हैं। कभी-कभी सिरदर्द या मतली भी हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको गंभीर दस्त, पेट में ऐंठन, या एलर्जी के लक्षण जैसे चेहरे, होंठ, या गले में सूजन दिखाई दे, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा का उपयोग डॉक्टर के निर्देशानुसार ही करें। उपयोग से पहले और बाद में हाथ धोएं। सपोजिटरी को रात में सोने से पहले योनि में गहराई तक डालें। माहवारी के दौरान इसका उपयोग न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। इस दवा को बच्चों की पहुंच से दूर रखें।
💊 cloclin 100mg/200mg vaginal capsule Uses & Benefits
[{"condition":"Bacterial vaginosis","description":"This medicine is used to treat bacterial vaginosis caused by susceptible anaerobic bacteria, helping to restore the normal vaginal flora.","evidence":"Well-established"},{"condition":"Vaginal candidiasis (yeast infection)","description":"The clotrimazole component treats vaginal yeast infections caused by Candida species, relieving itching, discharge, and irritation.","evidence":"Well-established"},{"condition":"Mixed vaginal infections","description":"This combination is effective when both bacterial vaginosis and a yeast infection are present simultaneously.","evidence":"Well-established"}]
Off-label uses: []
Primary treatment for: Mixed vaginal infections (bacterial vaginosis and vaginal candidiasis)
Also treats: Bacterial vaginosis, Vaginal candidiasis
📋 Drug Information
| Generic Name(s) | Clindamycin + Clotrimazole |
| Brand Name | Applygen Soft Gelatin Vaginal Suppositories |
| Manufacturer | Voizmed Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Antibiotic + Antifungal |
| Route of Administration | Vaginal |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Do not freeze. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works through two complementary mechanisms. Clindamycin binds to the 50S ribosomal subunit of susceptible bacteria, inhibiting protein synthesis and thereby stopping bacterial growth. Clotrimazole interferes with the synthesis of ergosterol, a vital component of fungal cell membranes, causing increased permeability and leakage of cellular contents, which leads to fungal cell death. Together, they provide antibacterial and antifungal action directly at the site of infection.
Mechanism Steps
💡 How to Take cloclin 100mg/200mg vaginal capsule
Strength: Vaginal suppository containing clindamycin 100 mg and clotrimazole 200 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one vaginal suppository inserted high into the vagina at bedtime for 7 consecutive days. The dose may be adjusted by your doctor based on the severity of the infection and your response to treatment. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dose adjustment is required for elderly patients. However, elderly patients may be more susceptible to side effects. Use with caution and follow your doctor's advice. |
| Renal Impairment | No dose adjustment is typically needed for renal impairment. Consult your doctor if you have severe kidney disease. |
| Hepatic Impairment | No dose adjustment is typically needed for hepatic impairment. However, monitor for side effects if you have severe liver disease. |
| Maximum Daily Dose | One suppository per day. |
Dosage Timeline
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cloclin 100mg/200mg vaginal capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Neuromuscular blockers | Major | |
| Erythromycin | Moderate | |
| CYP3A4 inhibitors | Moderate | |
| Oral contraceptives | Minor |
🚨 Major Interactions
- Warfarin
- Neuromuscular blocking agents (e.g., vecuronium)
⚡ Moderate Interactions
- Erythromycin
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
🍷 Alcohol Interaction
No specific interaction between alcohol and this vaginal medicine has been established. However, alcohol may worsen underlying conditions or interact with other medicines you are taking. It is advisable to limit alcohol consumption while being treated for an infection.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to clindamycin, clotrimazole, or any component of the formulation","History of inflammatory bowel disease or antibiotic-associated colitis","Use in children under 12 years of age (unless directed by a doctor)"]
⚠️ Warnings & Precautions
["Do not use this medicine if you have a history of allergy to clindamycin or clotrimazole.","Prolonged use may lead to overgrowth of non-susceptible organisms, including fungi.","If severe diarrhea occurs, stop the medicine and consult your doctor immediately.","Avoid contact with eyes, nose, or mouth.","Do not use during menstruation unless advised by your doctor.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]
🤱 Lactation Safety
It is not known whether clindamycin or clotrimazole passes into breast milk after vaginal administration. However, systemic absorption is low, so the risk to a nursing infant is likely minimal. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose with this vaginal suppository is unlikely due to its route of administration. If accidental ingestion occurs, seek medical attention immediately. Symptoms of overdose may include nausea, vomiting, and abdominal pain. Treatment is supportive and symptomatic.
⏰ Missed Dose
If you miss a dose, insert it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Additional Safety Advice
Use this medicine only as prescribed by your doctor. Wash your hands thoroughly before and after inserting the suppository. Insert it high into the vagina, preferably at bedtime, to allow it to dissolve overnight and minimize leakage. Avoid using tampons or having vaginal intercourse while using this medicine, as it may reduce effectiveness and increase irritation. Do not use this medicine during your menstrual period unless your doctor advises otherwise. If you are pregnant or breastfeeding, consult your doctor before use. Do not share this medicine with others, even if they have similar symptoms. Keep out of reach of children. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly women may be more prone to vaginal dryness and irritation. Use the suppository gently and consider using a water-based lubricant if needed. Monitor for side effects and consult your doctor if you have underlying health conditions.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. Both ingredients are generally considered safe, but your doctor will weigh the benefits and risks.
🏥 Post-Surgery Considerations
If you have recently had vaginal or pelvic surgery, consult your doctor before using this medicine to avoid irritation or complications.
🦷 Dental Procedures
No specific considerations for dental procedures. However, inform your dentist about all medicines you are taking.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
No specific exercise restrictions are required while using this medicine. However, if you experience discomfort or leakage, you may want to avoid strenuous activities immediately after insertion.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is used at bedtime and is unlikely to affect your daily work or activities. However, if you experience side effects like dizziness or headache, avoid driving or operating heavy machinery until you feel better.
🛑 When to Stop This Medicine
Stop using this medicine and consult your doctor if you experience severe side effects such as severe diarrhea, allergic reactions, or if your symptoms worsen. Do not stop the course early unless advised by your doctor, as this may lead to recurrence of infection.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended unless prescribed by a doctor. Prolonged use of clindamycin can lead to bacterial resistance or overgrowth of non-susceptible organisms. If you need treatment for more than 7 days, your doctor will monitor you for side effects and adjust therapy as needed.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Oral medications may be prescribed for systemic treatment, but they can have more side effects.
Evidence: Well-establishedProbiotics may help restore vaginal flora and prevent recurrence, but are not a primary treatment for active infection.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interaction between this medicine and vaccines has been established. You can receive vaccines as scheduled, but consult your doctor if you have concerns.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate or freeze
✅ DO
Keep in the original packaging
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label intact. Keep a copy of your prescription with you. Store at room temperature and protect from extreme heat or cold. If crossing time zones, continue with your regular bedtime schedule as closely as possible. No special customs documentation is typically required for personal use, but check local regulations.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling relief within 2-3 days, but it is important to complete the full 7-day course to fully clear the infection.
A: It is generally recommended to avoid using vaginal suppositories during your period. Consult your doctor for advice.
A: It is advisable to avoid vaginal intercourse during treatment to prevent irritation and ensure the medicine stays in place.
A: Both ingredients are generally considered safe in pregnancy when used as directed. However, consult your doctor before use.
🤔 Common Patient Concerns
🔄 Substitutes for cloclin 100mg/200mg vaginal capsule
View AllAlternative brands with exact same active ingredient:
-
Raclinda V 100mg/200mg PessariesRaj Bioceuticals ₹15.90 88.4% CHEAPER
-
vis 3 vaginal capsuleRapross Pharmaceuticals Pvt Ltd ₹42.85 68.6% CHEAPER
-
clima v 100mg/200mg vaginal capsuleDewcare Concept Pvt.Ltd. ₹50.00 63.4% CHEAPER
-
metrogyl v vaginal suppositoryJ B Chemicals and Pharmaceuticals Ltd ₹60.00 56% CHEAPER
-
clincin v 100mg/200mg tablet vtIndi Pharma ₹67.06 50.9% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Vaginal infections are caused by poor hygiene.
Fact: Vaginal infections can occur in any woman, regardless of hygiene. They are often caused by an imbalance in the natural vaginal flora. - Myth: You can stop using this medicine as soon as symptoms improve.
Fact: It is important to complete the full course of treatment to ensure the infection is fully eradicated and to prevent recurrence. - Myth: This medicine can be used for any vaginal discharge.
Fact: This medicine is specifically for mixed infections. Using it for other conditions may not be effective and could delay proper treatment.
🔄 Alternative Options
Generic Alternatives
- Clindamycin 100 mg + Clotrimazole 200 mg vaginal suppository (generic)
Brand Alternatives
- Candid-CL Vaginal Suppository