clobelan cream - Uses, Price, Side Effects & Substitutes
What is clobelan cream used for?
Clobin Cream (Clobetasol + Chlorocresol) is used to treat DERMA. It contains Clobetasol (0.05% w/w) + Chlorocresol (0.1% w/w), which Clobetasol: Binds to glucocorticoid receptors, inducing anti-inflammatory protei. Always consult your doctor before use. Take as prescribed.
- Generic Name: Clobetasol + Chlorocresol
- Manufacturer: Tweet India Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ clobelan cream Uses & Benefits
Eczema, psoriasis, dermatitis, allergic reactions, inflammatory skin conditions with secondary infection.
Off-label uses: Lichen planus, discoid lupus erythematosus.
๐ Drug Information
| Generic Name(s) | Clobetasol + Chlorocresol |
| Brand Name | Clobin Cream |
| Manufacturer | Tweet India Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | Corticosteroid (Clobetasol) + Antimicrobial (Chlorocresol) |
| Route of Administration | Topical. |
| Storage | Store at 20-25ยฐC (68-77ยฐF); keep tightly closed. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Clobetasol: Binds to glucocorticoid receptors, inducing anti-inflammatory proteins and suppressing inflammatory mediators. Chlorocresol: Disrupts microbial cell membranes and inhibits growth.
Mechanism Steps
๐ก How to Take clobelan cream
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of clobelan cream
โ Common Side Effects
- Burning
- itching
- irritation
- dryness
- folliculitis
๐จ Serious Side Effects
- Skin atrophy
- striae
- adrenal suppression
- secondary infection
โ ๏ธ Rare Side Effects
- Allergic contact dermatitis
- hypertrichosis
- hypopigmentation
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| CYP3A4 inhibitors | Major | Increased systemic exposure to clobetasol |
| Other topical corticosteroids | Major | Additive effects and increased risk of skin atrophy |
๐จ Major Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
- Other topical corticosteroids
โก Moderate Interactions
- Antidiabetic agents
- Antihypertensives
โน๏ธ Minor Interactions
- None significant
๐ฝ๏ธ Food Interactions
None known.
๐ท Alcohol Interaction
No known interaction.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to components, untreated bacterial/fungal/viral infections, rosacea, perioral dermatitis.
๐ Monitoring Parameters
Skin condition, signs of infection, adrenal suppression with prolonged use.
๐คฑ Lactation Safety
Use with caution; avoid application to breast area.
๐ Overdose Management
Topical overdose unlikely; if ingested, symptomatic treatment.
โฐ Missed Dose
Apply as soon as remembered; skip if almost time for next dose.