clitz 100mg/100mg/100mg soft gelatin capsule - Clindamycin (100mg) + Clotrimazole (100mg) medicine

Clitz 100mg/100mg/100mg Soft Gelatin Capsule: Complete Medicine Guide

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🏭 Merganzer Pharma Private Limited 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 21, 2026
🤰 Pregnancy Category Not established from the available information. Clindamycin is generally considered acceptable during pregnancy when clearly needed, but clotrimazole oral use is not recommended. Consult your doctor. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for combination in mixed infections; limited for specific product.
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe or bloody diarrhea
  • Signs of allergic reaction: rash, itching, swelling of face/lips/throat, difficulty breathing
  • Yellowing of skin or eyes (jaundice)
  • Severe abdominal pain
  • Unusual bleeding or bruising
  • Persistent vomiting
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is clitz 100mg/100mg/100mg soft gelatin capsule used for?

This medicine is a prescription soft gelatin capsule containing clindamycin 100 mg and clotrimazole 100 mg. It is used to treat mixed bacterial and fungal infections of the female genital tract. It works by killing bacteria and fungi. Take it exactly as prescribed by your doctor.

  • Generic Name: Clindamycin + Clotrimazole
  • Manufacturer: Merganzer Pharma Private Limited
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 clitz 100mg/100mg/100mg soft gelatin capsule के बारे में (Hindi Summary)

उपयोग: यह दवा क्लिंडामाइसिन और क्लोट्रिमाज़ोल का संयोजन है, जिसका उपयोग महिलाओं के जननांग पथ में होने वाले मिश्रित बैक्टीरियल और फंगल संक्रमणों के इलाज के लिए किया जाता है। यह बैक्टीरिया और फंगस दोनों को मारती है। इसका सेवन डॉक्टर के निर्देशानुसार ही करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द और मुँह में धातु जैसा स्वाद शामिल हैं। गंभीर दुष्प्रभावों में गंभीर दस्त, एलर्जी प्रतिक्रिया, और यकृत की समस्या शामिल हो सकती है। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। पूरा कोर्स पूरा करें, भले ही आप बेहतर महसूस करें। इसे भोजन के साथ या बिना भोजन के ले सकते हैं, लेकिन पेट खराब होने पर भोजन के साथ लें। शराब का सेवन न करें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें। इसे बच्चों की पहुँच से दूर रखें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 clitz 100mg/100mg/100mg soft gelatin capsule Uses & Benefits

[{"condition":"Bacterial vaginosis with concurrent vulvovaginal candidiasis","description":"This medicine is used to treat mixed infections of the vagina caused by both bacteria and fungi, providing broad coverage.","evidence":"Well-established"},{"condition":"Vulvovaginal candidiasis complicated by bacterial infection","description":"It helps eradicate fungal overgrowth while also targeting associated bacterial pathogens.","evidence":"Well-established"},{"condition":"Other mixed bacterial-fungal infections of the genital tract","description":"May be prescribed when a clinician determines that both clindamycin and clotrimazole are needed.","evidence":"Limited"}]

Off-label uses: [{"condition":"Bacterial vaginosis alone","description":"Sometimes used off-label when clotrimazole is added for suspected fungal co-infection, but not standard.","evidence":"Limited"},{"condition":"Prevention of infection after gynecological procedures","description":"Rarely, it may be used prophylactically, but evidence is lacking.","evidence":"Insufficient"}]

Primary treatment for: Mixed bacterial and fungal infections of the female genital tract

Also treats: Bacterial vaginosis with candidiasis, Vulvovaginal candidiasis with bacterial co-infection

📋 Drug Information

Generic Name(s)Clindamycin + Clotrimazole
Brand NameClitz
ManufacturerMerganzer Pharma Private Limited
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassAntibiotic + Antifungal
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture, unless otherwise specified on the packaging.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food if it causes stomach upset.
2
Complete the full course as prescribed, even if symptoms improve.
3
Avoid alcohol while taking this medicine to prevent nausea and liver stress.
4
Report any severe or bloody diarrhea immediately, as it may indicate a serious gut infection.
5
Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.
6
Do not share this medicine with others, even if they have similar symptoms.
7
Store in a cool, dry place away from direct sunlight.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Vaginal discharge
This medicine is commonly prescribed for mixed infections causing discharge.
Likely Use
✅
Vaginal itching
It helps relieve itching caused by fungal and bacterial infections.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
❌
Common cold
It is not effective against viral infections.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionClindamycin is rapidly absorbed after oral administration, with peak plasma concentrations reached within 1 hour. Clotrimazole is poorly absorbed from the gastrointestinal tract when taken orally; its systemic absorption is minimal, and it acts primarily within the gut lumen or topically. Not established from the available information for the specific combination product.
DistributionClindamycin is widely distributed in body fluids and tissues, including bone, but does not reach significant levels in cerebrospinal fluid. Clotrimazole, when absorbed, is distributed to various tissues, but systemic distribution is limited due to poor oral absorption. Not established from the available information for the specific combination product.
Protein BindingClindamycin is approximately 90% bound to plasma proteins. Clotrimazole is highly protein-bound (approximately 90% or more) when it enters the systemic circulation. Not established from the available information for the specific combination product.
MetabolismClindamycin is metabolized in the liver, primarily by CYP3A4, to active and inactive metabolites. Clotrimazole is metabolized in the liver by CYP3A4 to several metabolites. Not established from the available information for the specific combination product.
Half-LifeThe elimination half-life of clindamycin is approximately 2 to 3 hours in adults with normal renal function. The elimination half-life of clotrimazole is not well established after oral administration due to poor absorption. Not established from the available information for the specific combination product.
ExcretionClindamycin and its metabolites are excreted primarily in urine and bile, with some in feces. Clotrimazole is excreted mainly in feces as unchanged drug and metabolites. Not established from the available information for the specific combination product.
BioavailabilityThe oral bioavailability of clindamycin is approximately 90% in fasting conditions. The oral bioavailability of clotrimazole is very low (less than 10%) due to poor absorption. Not established from the available information for the specific combination product.
Onset of ActionThe onset of action for clindamycin is within 1 to 2 hours after oral administration. For clotrimazole, the onset is not well defined when taken orally, as it acts locally. Not established from the available information for the specific combination product.
Peak Plasma TimeClindamycin reaches peak plasma concentrations in about 1 hour after oral administration. Clotrimazole peak plasma levels are negligible after oral intake. Not established from the available information for the specific combination product.
Duration of ActionThe duration of action for clindamycin is typically 6 to 8 hours, requiring multiple daily dosing. For clotrimazole, the duration is not well established for oral use. Not established from the available information for the specific combination product.

How It Works

This medicine combines two active ingredients with distinct mechanisms. Clindamycin binds to the 50S ribosomal subunit of susceptible bacteria, inhibiting protein synthesis and thereby stopping bacterial growth. Clotrimazole interferes with the synthesis of ergosterol, a vital component of fungal cell membranes, leading to increased membrane permeability and leakage of cellular contents, which results in fungal cell death. Together, they provide antibacterial and antifungal activity.

Mechanism Steps

1
Clindamycin binding: Clindamycin binds to the 50S ribosomal subunit of bacteria, preventing peptide bond formation and inhibiting protein synthesis.
2
Clotrimazole action: Clotrimazole inhibits the fungal enzyme 14α-demethylase, blocking ergosterol synthesis and damaging the fungal cell membrane.
3
Combined effect: The combined actions lead to the inhibition of bacterial growth and the destruction of fungal cells, resolving mixed infections.

💡 How to Take clitz 100mg/100mg/100mg soft gelatin capsule

Strength: Soft gelatin capsule containing clindamycin 100 mg and clotrimazole 100 mg.

1Swallow the capsule whole with a full glass of water.
2Take with or without food, but if stomach upset occurs, take with a meal.
3Do not crush, chew, or open the capsule.
4Take at the same time each day to maintain consistent levels.
5Complete the full course as prescribed, even if you feel better.
6If you miss a dose, follow the missed dose instructions.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one capsule taken orally once or twice daily, or as directed by your physician. The exact dose and duration depend on the type and severity of the infection, your age, weight, kidney and liver function, and other medications you may be taking. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially gastrointestinal side effects. Dose adjustment may be necessary based on renal and hepatic function. Consult your doctor.
Renal ImpairmentIn patients with severe renal impairment, dose adjustment of clindamycin may be required. Clotrimazole absorption is minimal, so no adjustment is needed. Consult your doctor for individualized dosing.
Hepatic ImpairmentIn patients with severe hepatic impairment, dose adjustment of clindamycin may be necessary. Clotrimazole is metabolized in the liver, but systemic absorption is low. Consult your doctor for individualized dosing.
Maximum Daily DoseThe maximum recommended daily dose is not established from the available information. Follow your doctor's prescription.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and nausea.
Grapefruit
Avoid large amounts
May increase clotrimazole levels, though systemic absorption is low.
Alcohol
Avoid
May worsen side effects like nausea and abdominal pain.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of clitz 100mg/100mg/100mg soft gelatin capsule

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Diarrhea (Common (5-10%))
Stay hydrated. If diarrhea is severe or bloody, seek medical attention immediately.
Abdominal pain (Common (5-10%))
Usually temporary. If severe, contact your doctor.
Metallic taste (Common (5-10%))
Usually resolves on its own. Chewing sugar-free gum may help.
Vomiting (Uncommon (1-5%))
Take with food and fluids. If persistent, consult your doctor.

🚨 Serious Side Effects

Clostridium difficile-associated diarrhea (Rare (<0.1%))
Seek immediate medical attention if you develop watery diarrhea, fever, or abdominal cramps.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Call emergency services if you experience swelling of face, lips, throat, difficulty breathing, or rash.
Severe skin reactions (e.g., Stevens-Johnson syndrome) (Very rare (<0.01%))
Stop the medicine and seek immediate medical help if you notice blistering, peeling, or sores in mouth or eyes.
Liver toxicity (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe fatigue to your doctor immediately.

⚠️ Rare Side Effects

Blood dyscrasias (e.g., leukopenia, thrombocytopenia)
Report unusual bruising or bleeding, or signs of infection, to your doctor.
Esophageal ulceration
Take with a full glass of water and remain upright for 30 minutes. Report severe chest pain or difficulty swallowing.
Polyarthritis
Consult your doctor if you experience joint pain or swelling.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Neuromuscular blockers Major
Erythromycin Major
CYP3A4 inhibitors Moderate
CYP3A4 inducers Moderate
Antacids Minor
Kaolin-pectin Minor

🚨 Major Interactions

  • Warfarin
  • Neuromuscular blocking agents (e.g., vecuronium)
  • Erythromycin

⚡ Moderate Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
  • CYP3A4 inducers (e.g., rifampin, carbamazepine)

🍷 Alcohol Interaction

Alcohol may worsen certain side effects of this medicine, such as nausea, vomiting, and abdominal pain. It is advisable to avoid alcohol while taking this medicine to reduce the risk of gastrointestinal discomfort and potential liver effects.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to clindamycin, clotrimazole, or any component of the formulation.","History of antibiotic-associated colitis.","Inflammatory bowel disease (e.g., Crohn's disease, ulcerative colitis).","Severe liver impairment.","Use in patients with a history of Clostridium difficile infection."]

⚠️ Warnings & Precautions

["Use with caution in patients with renal or hepatic impairment; dose adjustment may be required.","Avoid in patients with a history of gastrointestinal disease, especially colitis.","May cause overgrowth of non-susceptible organisms; monitor for superinfections.","Do not use for viral infections (e.g., common cold).","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.","Avoid alcohol during treatment.","Do not share this medicine with others."]

🤱 Lactation Safety

Clindamycin is excreted in breast milk and may cause diarrhea or thrush in the infant. Clotrimazole is poorly absorbed orally, but it is not known if it is excreted in breast milk. Consult your doctor before breastfeeding.

💊 Overdose Management

Overdose may cause severe nausea, vomiting, diarrhea, and abdominal pain. There is no specific antidote. Treatment is supportive and symptomatic. In case of overdose, seek immediate medical attention. Contact a poison control center if available.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop treatment early, even if you feel better, as this can lead to resistance or recurrence of infection. Swallow the capsule whole with a full glass of water. You may take it with or without food, but if it upsets your stomach, take it with a meal. Avoid alcohol while taking this medicine, as it may worsen side effects like nausea and dizziness. Inform your doctor if you have kidney or liver problems, as dose adjustments may be needed. Do not use this medicine if you are allergic to clindamycin, clotrimazole, or similar medications. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before use. Keep this medicine out of reach of children. Store it at room temperature, away from moisture and heat. Do not use it after the expiry date. If you experience severe diarrhea, bloody stools, or signs of an allergic reaction, seek medical help immediately.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to gastrointestinal side effects and should be monitored closely. Dose adjustment may be needed based on kidney and liver function.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. Clindamycin may be used if clearly needed, but oral clotrimazole is not recommended during pregnancy.

🏥 Post-Surgery Considerations

If you have recently had surgery, inform your surgeon about this medicine. It may interact with other medications or affect wound healing.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may interact with other medications used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain good genital hygiene.
🥗
Wear breathable cotton underwear.
😴
Avoid douching and scented feminine products.
💧
Complete the full course of treatment.
🧘
Follow up with your doctor if symptoms persist.
🌞
Stay hydrated and eat a balanced diet.

🏋️ Exercise Considerations

No specific exercise restrictions are known while taking this medicine. However, if you experience dizziness or fatigue, avoid strenuous activities until you feel better.

🥗 Diet Recommendations

Include probiotics like yogurt to maintain healthy gut flora.
Stay well hydrated.
Avoid excessive sugar and processed foods.
Eat a balanced diet rich in fruits and vegetables.

💼 Impact on Daily Work & Life

This medicine is unlikely to affect your ability to drive or operate machinery. However, if you experience dizziness, nausea, or fatigue, avoid these activities until you feel well.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early may lead to recurrence of infection and resistance. If you experience severe side effects, contact your doctor immediately for advice.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to overgrowth of non-susceptible organisms, including fungi or resistant bacteria. It may also increase the risk of Clostridium difficile infection. Regular monitoring of liver and kidney function may be advised if used for prolonged periods. Do not use for longer than prescribed without medical supervision.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Probiotics

May help restore healthy vaginal flora and prevent recurrence.

Evidence: Limited
Proper hygiene practices

Can reduce the risk of infections.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, inform your doctor if you are due for any vaccinations.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If crossing time zones, adjust dosing times gradually as advised by your doctor. Check local customs regulations for carrying prescription medicines. Always keep it in your carry-on luggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 32-year-old woman with vaginal discharge and itching
She was diagnosed with mixed bacterial and fungal infection and prescribed this medicine. After 3 days, her symptoms improved significantly. She completed the 7-day course and felt completely better. She was advised to take it with food to avoid nausea.
💡 Lesson: Taking the full course and following dietary advice improves outcomes and reduces side effects.
👤 A 45-year-old woman with recurrent vaginal infections
She had tried several over-the-counter remedies without success. Her doctor prescribed this medicine after proper diagnosis. She experienced mild nausea initially but it subsided when she took it with meals. The infection cleared within a week.
💡 Lesson: Proper diagnosis and prescription treatment are essential for recurrent infections; do not self-medicate.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 2-3 days, but it is important to complete the full course as prescribed, usually 7 days or as directed by your doctor.

Q: Can I take this medicine with other medications?

A: Inform your doctor about all other medicines you are taking, especially blood thinners, as interactions may occur.

Q: Is it safe during pregnancy?

A: Consult your doctor. Clindamycin is generally acceptable when needed, but oral clotrimazole is not recommended during pregnancy.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for clitz 100mg/100mg/100mg soft gelatin capsule

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any vaginal infection.
    Fact: It is only effective against specific bacteria and fungi. It does not treat viral or other infections.
  • Myth: You can stop taking it once symptoms improve.
    Fact: You must complete the full course to prevent recurrence and resistance.
  • Myth: It is safe to use without a prescription.
    Fact: It is a prescription medicine and should only be used under medical supervision.

🔄 Alternative Options

Generic Alternatives

  • Clindamycin 100 mg + Clotrimazole 100 mg soft gelatin capsules (various manufacturers)

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Clindamycin 100 mg + Clotrimazole 100 mg","route":"Oral","primary_use":"Mixed bacterial and fungal genital infections"},{"medicine":"Clindamycin alone","composition":"Clindamycin 100 mg","route":"Oral","primary_use":"Bacterial infections only"},{"medicine":"Clotrimazole alone","composition":"Clotrimazole 100 mg","route":"Oral","primary_use":"Fungal infections only"}]

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