clinmide gel
What is clinmide gel used for?
Acnetoin Gel (Clindamycin + Nicotinamide) is used to treat DERMA. It contains Clindamycin (1% w/w) + Nicotinamide (4% w/w), which Clindamycin inhibits bacterial protein synthesis by binding to 50S ribosomal sub. Always consult your doctor before use. Take as prescribed.
- Generic Name: Clindamycin + Nicotinamide
- Manufacturer: Moraceae Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ clinmide gel Uses & Benefits
Acne vulgaris, inflammatory acne.
Off-label uses: Rosacea, perioral dermatitis.
๐ Drug Information
| Generic Name(s) | Clindamycin + Nicotinamide |
| Brand Name | Acnetoin Gel |
| Manufacturer | Moraceae Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | Antibiotic + Vitamin B3 derivative |
| Route of Administration | Topical |
| Storage | Store at room temperature (20-25ยฐC), away from moisture and heat. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Clindamycin inhibits bacterial protein synthesis by binding to 50S ribosomal subunit; Nicotinamide reduces sebum production and has anti-inflammatory effects.
Mechanism Steps
๐ก How to Take clinmide gel
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of clinmide gel
โ Common Side Effects
- Skin dryness
- Peeling
- Erythema
- Burning sensation
๐จ Serious Side Effects
- Pseudomembranous colitis
- Severe allergic reactions
โ ๏ธ Rare Side Effects
- Contact dermatitis
- Urticaria
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Neuromuscular blocking agents | Major | Enhanced neuromuscular blockade |
| Erythromycin | Major | Antagonism of clindamycin effect |
| Other topical antibiotics | Moderate | Possible additive irritation |
| Retinoids | Moderate | Increased skin irritation |
๐จ Major Interactions
- Neuromuscular blocking agents
- Erythromycin
โก Moderate Interactions
- Other topical antibiotics
- Retinoids
โน๏ธ Minor Interactions
- None significant
๐ฝ๏ธ Food Interactions
None known.
๐ท Alcohol Interaction
No known interaction.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to clindamycin, nicotinamide, or any component; history of antibiotic-associated colitis.
๐ Monitoring Parameters
Skin irritation, signs of hypersensitivity, improvement in acne lesions.
๐คฑ Lactation Safety
Clindamycin is excreted in breast milk; use with caution. Nicotinamide is safe.
๐ Overdose Management
Topical overdose unlikely; if ingested, symptomatic and supportive care.
โฐ Missed Dose
Apply as soon as remembered; skip if almost time for next dose.