clindafin n gel
What is clindafin n gel used for?
Acnetoin Gel (Clindamycin + Nicotinamide) is used to treat DERMA. It contains Clindamycin (1% w/w) + Nicotinamide (4% w/w), which Clindamycin inhibits bacterial protein synthesis by binding to 50S ribosomal sub. Always consult your doctor before use. Take as prescribed.
- Generic Name: Clindamycin + Nicotinamide
- Manufacturer: HBC Dermiza Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ clindafin n gel Uses & Benefits
Acne vulgaris, inflammatory acne.
Off-label uses: Rosacea, perioral dermatitis.
๐ Drug Information
| Generic Name(s) | Clindamycin + Nicotinamide |
| Brand Name | Acnetoin Gel |
| Manufacturer | HBC Dermiza Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | Antibiotic + Vitamin B3 derivative |
| Route of Administration | Topical |
| Storage | Store at room temperature (20-25ยฐC), away from moisture and heat. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Clindamycin inhibits bacterial protein synthesis by binding to 50S ribosomal subunit; Nicotinamide reduces sebum production and has anti-inflammatory effects.
Mechanism Steps
๐ก How to Take clindafin n gel
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of clindafin n gel
โ Common Side Effects
- Skin dryness
- Peeling
- Erythema
- Burning sensation
๐จ Serious Side Effects
- Pseudomembranous colitis
- Severe allergic reactions
โ ๏ธ Rare Side Effects
- Contact dermatitis
- Urticaria
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Neuromuscular blocking agents | Major | Enhanced neuromuscular blockade |
| Erythromycin | Major | Antagonism of clindamycin effect |
| Other topical antibiotics | Moderate | Possible additive irritation |
| Retinoids | Moderate | Increased skin irritation |
๐จ Major Interactions
- Neuromuscular blocking agents
- Erythromycin
โก Moderate Interactions
- Other topical antibiotics
- Retinoids
โน๏ธ Minor Interactions
- None significant
๐ฝ๏ธ Food Interactions
None known.
๐ท Alcohol Interaction
No known interaction.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to clindamycin, nicotinamide, or any component; history of antibiotic-associated colitis.
๐ Monitoring Parameters
Skin irritation, signs of hypersensitivity, improvement in acne lesions.
๐คฑ Lactation Safety
Clindamycin is excreted in breast milk; use with caution. Nicotinamide is safe.
๐ Overdose Management
Topical overdose unlikely; if ingested, symptomatic and supportive care.
โฐ Missed Dose
Apply as soon as remembered; skip if almost time for next dose.
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Good quality medicine. Satisfied with the outcome.
Good quality medicine. Satisfied with the outcome.
This medicine was effective for me. I followed the doctor's advice.
Good quality medicine. Satisfied with the outcome.
Good quality medicine. Satisfied with the outcome.