clenchin-z gel - Clindamycin (1% w/w) + Zinc acetate (1% w/w) medicine

clenchin-z gel - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Rowan Bioceuticals Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 29, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 29, 2026

What is clenchin-z gel used for?

Acnelak-CLZ Cream (Clindamycin + Zinc acetate) is used to treat DERMA. It contains Clindamycin (1% w/w) + Zinc acetate (1% w/w), which Clindamycin inhibits bacterial protein synthesis by binding to 50S ribosomal sub. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Clindamycin + Zinc acetate
  • Manufacturer: Rowan Bioceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š clenchin-z gel Uses & Benefits

Acne vulgaris (inflammatory and non-inflammatory lesions)

Off-label uses: Bacterial skin infections, Rosacea

๐Ÿ“‹ Drug Information

Generic Name(s)Clindamycin + Zinc acetate
Brand NameAcnelak-CLZ Cream
ManufacturerRowan Bioceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassTopical antibiotic + Anti-inflammatory
Route of AdministrationTopical
StorageStore at 20-25ยฐC; protect from light and moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMinimal systemic absorption after topical application
DistributionPrimarily localized to skin; negligible systemic distribution
Protein BindingClindamycin: ~94% bound to plasma proteins
MetabolismClindamycin: Hepatic metabolism via CYP3A4; Zinc acetate: Not metabolized
Half-LifeClindamycin: 2-3 hours (systemic); Zinc: Not applicable
ExcretionClindamycin: Renal and biliary; Zinc: Fecal
BioavailabilityLow systemic bioavailability due to topical route
Onset of ActionWithin a few days to weeks
Peak Plasma TimeNot applicable (topical)
Duration of ActionSustained with regular application

How It Works

Clindamycin inhibits bacterial protein synthesis by binding to 50S ribosomal subunit; Zinc acetate reduces inflammation and sebum production

Mechanism Steps

1Clindamycin binds to 50S ribosomal subunit of bacteria
2Inhibits peptide bond formation and protein synthesis
3Reduces bacterial growth and colonization

๐Ÿ’ก How to Take clenchin-z gel

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of clenchin-z gel

โœ… Common Side Effects

  • Skin dryness
  • Peeling
  • Erythema
  • Burning sensation

๐Ÿšจ Serious Side Effects

  • Pseudomembranous colitis
  • Severe allergic reactions

โš ๏ธ Rare Side Effects

  • Contact dermatitis
  • Urticaria

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Neuromuscular blocking agents Major Enhanced neuromuscular blockade
Erythromycin Major Antagonism of antibacterial effect

๐Ÿšจ Major Interactions

  • Neuromuscular blocking agents
  • Erythromycin

โšก Moderate Interactions

  • Other topical antibiotics
  • Retinoids

โ„น๏ธ Minor Interactions

  • Benzoyl peroxide

๐Ÿท Alcohol Interaction

No known interaction

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to clindamycin, zinc, or any component; history of antibiotic-associated colitis

๐Ÿ“Š Monitoring Parameters

Skin irritation, allergic reactions, improvement in acne lesions

๐Ÿคฑ Lactation Safety

Considered safe; minimal systemic absorption

๐Ÿ’Š Overdose Management

Unlikely with topical use; if ingested, symptomatic treatment

โฐ Missed Dose

Apply as soon as remembered; skip if almost time for next dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 29, 2026

๐Ÿ”— View Profile

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