clearzit soap - Azelaic Acid (2.5% w/w) medicine

clearzit soap

4.8 (13 reviews)
๐Ÿญ Grace Derma Healthcare Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is clearzit soap used for?

Aziderm 20% Cream (Azelaic Acid) is used to treat DERMA. It contains Azelaic Acid (2.5% w/w), which Inhibits microbial protein synthesis and reduces keratinocyte proliferation; ant. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Azelaic Acid
  • Manufacturer: Grace Derma Healthcare Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: B
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š clearzit soap Uses & Benefits

Acne vulgaris, rosacea, melasma.

Off-label uses: Hyperpigmentation, perioral dermatitis.

๐Ÿ“‹ Drug Information

Generic Name(s)Azelaic Acid
Brand NameAziderm 20% Cream
ManufacturerGrace Derma Healthcare Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassAntimicrobials- Acne
Route of AdministrationTopical
StorageStore at 20-25ยฐC (68-77ยฐF); keep tightly closed.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionApproximately 4% of topically applied azelaic acid is absorbed percutaneously.
DistributionDistributed into the skin layers; systemic distribution is minimal.
Protein BindingNot significantly bound to plasma proteins.
MetabolismPartially metabolized via beta-oxidation to shorter-chain dicarboxylic acids.
Half-LifeApproximately 12 hours (topical application).
ExcretionRenal excretion of metabolites and unchanged drug.
BioavailabilityLow systemic bioavailability (about 4% after topical application).
Onset of Action2-4 weeks for visible improvement in acne.
Peak Plasma TimeNot applicable for topical use; systemic levels are low.
Duration of ActionSustained with regular application.

How It Works

Inhibits microbial protein synthesis and reduces keratinocyte proliferation; anti-inflammatory effects.

Mechanism Steps

1Inhibits bacterial protein synthesis in Propionibacterium acnes
2Reduces keratinocyte proliferation and follicular hyperkeratinization
3Decreases inflammation by inhibiting neutrophil reactive oxygen species

๐Ÿ’ก How to Take clearzit soap

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of clearzit soap

โœ… Common Side Effects

  • Pruritus
  • Burning
  • Stinging
  • Erythema
  • Dryness

๐Ÿšจ Serious Side Effects

  • Severe allergic reaction (rare)

โš ๏ธ Rare Side Effects

  • Hypopigmentation
  • Contact dermatitis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

๐Ÿฝ๏ธ Food Interactions

None known.

๐Ÿท Alcohol Interaction

No known interaction.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to azelaic acid or any component.

๐Ÿ“Š Monitoring Parameters

Skin irritation, improvement in acne lesions.

๐Ÿคฑ Lactation Safety

Use with caution; not known if excreted in breast milk.

๐Ÿ’Š Overdose Management

Unlikely with topical use; if ingested, symptomatic treatment.

โฐ Missed Dose

Apply as soon as remembered; skip if almost time for next dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

โญ User Reviews

Happy Patient Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Certified Buyer Jul 10, 2026

Effective and reliable. Worked as expected.

Happy Patient Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Certified Buyer Jul 10, 2026

Effective and reliable. Worked as expected.

Happy Patient Jul 10, 2026

Found this to be a helpful product. Good results.

๐Ÿ˜Š Was this information helpful?

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