cleanish vaginal cream
What is cleanish vaginal cream used for?
Applygen Soft Gelatin Vaginal Suppositories (Clindamycin + Clotrimazole) is used to treat ANTI INFECTIVES. It contains Clindamycin (NA) + Clotrimazole (NA), which Clindamycin inhibits bacterial protein synthesis by binding to 50S ribosomal sub. Always consult your doctor before use. Take as prescribed.
- Generic Name: Clindamycin + Clotrimazole
- Manufacturer: Colinz Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ cleanish vaginal cream Uses & Benefits
Bacterial vaginosis, vulvovaginal candidiasis, mixed vaginal infections
Off-label uses: Prevention of post-surgical vaginal infections
๐ Drug Information
| Generic Name(s) | Clindamycin + Clotrimazole |
| Brand Name | Applygen Soft Gelatin Vaginal Suppositories |
| Manufacturer | Colinz Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Antibiotic + Antifungal |
| Route of Administration | Vaginal |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Clindamycin inhibits bacterial protein synthesis by binding to 50S ribosomal subunit; Clotrimazole inhibits fungal ergosterol synthesis by inhibiting 14ฮฑ-demethylase
Mechanism Steps
๐ก How to Take cleanish vaginal cream
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of cleanish vaginal cream
โ Common Side Effects
- Vaginal burning
- itching
- irritation
- abdominal cramps
๐จ Serious Side Effects
- Pseudomembranous colitis
- severe allergic reactions
โ ๏ธ Rare Side Effects
- Hepatotoxicity
- Stevens-Johnson syndrome
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Neuromuscular blockers | Major | Enhanced neuromuscular blockade |
๐จ Major Interactions
- Neuromuscular blocking agents
- Warfarin
โก Moderate Interactions
- CYP3A4 inhibitors
- CYP3A4 inducers
โน๏ธ Minor Interactions
- Oral contraceptives
๐ฝ๏ธ Food Interactions
No significant food interactions
๐ท Alcohol Interaction
No known interaction
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to clindamycin, clotrimazole, or any component; history of pseudomembranous colitis
๐ Monitoring Parameters
Clinical response, signs of superinfection, hypersensitivity reactions
๐คฑ Lactation Safety
Use with caution; minimal systemic absorption
๐ Overdose Management
Unlikely due to local use; symptomatic treatment if ingested
โฐ Missed Dose
Insert as soon as remembered; skip if near next dose; do not double dose