Bronfix Lb Oral Suspension Orange: A Comprehensive Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Persistent diarrhea lasting more than 3 days
If experiencing severe symptoms, call emergency services immediately.
What is cifigold dry syrup used for?
This medicine is a combination of cefixime, an antibiotic, and lactobacillus, a probiotic. It is used to treat bacterial infections like ear infections, sinusitis, and urinary tract infections. The antibiotic kills bacteria, while the probiotic helps prevent diarrhea.
- Generic Name: Cefixime + Lactobacillus
- Manufacturer: Pharmasynth Formulations Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cifigold dry syrup के बारे में (Hindi Summary)
उपयोग: यह दवा सेफिक्साइम और लैक्टोबैसिलस का संयोजन है। इसका उपयोग बैक्टीरियल संक्रमण जैसे कान का संक्रमण, साइनसाइटिस, ब्रोंकाइटिस और मूत्र मार्ग संक्रमण के इलाज के लिए किया जाता है। सेफिक्साइम बैक्टीरिया को मारता है और लैक्टोबैसिलस पेट में अच्छे बैक्टीरिया को बनाए रखने में मदद करता है, जिससे दस्त का खतरा कम होता है।
साइड इफेक्ट्स: आम दुष्प्रभावों में दस्त, मतली, पेट दर्द और सिरदर्द शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, गंभीर दस्त, या लीवर की समस्या हो सकती है। यदि आपको लगातार दस्त, दाने, या आंखों या त्वचा का पीलापन दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। उपयोग से पहले बोतल को अच्छी तरह हिलाएं। सही मात्रा मापने के लिए मापने वाला चम्मच या कप का उपयोग करें। दवा का कोर्स पूरा करें, भले ही आप बेहतर महसूस करें। यदि आपको गुर्दे की बीमारी, पेट की समस्या, या एंटीबायोटिक से एलर्जी है तो डॉक्टर को बताएं। एंटासिड या आयरन सप्लीमेंट इस दवा से 2 घंटे पहले या बाद में लें।
💊 cifigold dry syrup Uses & Benefits
- [{"condition":"Acute otitis media","description":"Treats middle ear infections caused by susceptible bacteria like Streptococcus pneumoniae and Haemophilus influenzae.","evidence":"Well-established"},{"condition":"Sinusitis","description":"Effective against bacterial sinus infections when caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Bronchitis","description":"Used for acute exacerbations of chronic bronchitis caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"Treats uncomplicated UTIs caused by susceptible strains of E.
- coli and Klebsiella.","evidence":"Well-established"},{"condition":"Pharyngitis and tonsillitis","description":"Effective against streptococcal throat infections when penicillin is not suitable.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Gonorrhea","description":"Sometimes used as an alternative treatment for uncomplicated gonorrhea, but resistance patterns vary.","evidence":"Limited"},{"condition":"Typhoid fever","description":"May be used in some regions for typhoid fever, but resistance is common and other agents are preferred.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Otitis media, Sinusitis, Bronchitis, Urinary tract infections, Pharyngitis
📋 Drug Information
| Generic Name(s) | Cefixime + Lactobacillus |
| Brand Name | Afix 200mg Tablet |
| Manufacturer | Pharmasynth Formulations Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Third-generation cephalosporin antibiotic + Probiotic |
| Route of Administration | Oral |
| Storage | Store the dry powder at room temperature (15-30°C). After reconstitution, store the suspension in the refrigerator (2-8°C). Do not freeze. Keep the bottle tightly closed. Discard any unused suspension after 14 days. |
| Shelf Life | The shelf life of the dry powder is typically 24 months from the date of manufacture. After reconstitution, use within 14 days if stored in the refrigerator. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Cefixime, the antibiotic component, works by binding to penicillin-binding proteins (PBPs) inside the bacterial cell wall. This binding inhibits the cross-linking of peptidoglycan chains, which are essential for the strength and rigidity of the bacterial cell wall. As a result, the bacterial cell wall becomes weak and the bacterium eventually dies due to osmotic pressure. Lactobacillus, the probiotic component, helps restore and maintain the natural balance of beneficial bacteria in the gastrointestinal tract, which can be disrupted by antibiotic therapy. This combination helps reduce the risk of antibiotic-associated diarrhea.
Mechanism Steps
💡 How to Take cifigold dry syrup
Strength: Each 5 mL of oral suspension contains cefixime 50 mg and lactobacillus 60 million spores.
Dosage Information
| Adult Dosage | The usual adult dose of cefixime is 400 mg per day, which can be taken as a single daily dose or divided into two doses of 200 mg every 12 hours. For uncomplicated urinary tract infections, a dose of 400 mg once daily is often used. For other infections, the dose may vary. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. Typically, cefixime is dosed based on weight (e.g., 8 mg/kg/day), but this must be determined by a doctor. |
| Elderly Dosage | Elderly patients may have reduced renal function and may require dose adjustment. The dose must be individualized by a qualified clinician based on renal function. |
| Renal Impairment | In patients with renal impairment (creatinine clearance < 60 mL/min), the dose of cefixime should be adjusted. For creatinine clearance 21-60 mL/min, the usual dose is 300 mg once daily. For creatinine clearance < 20 mL/min, the dose is 200 mg once daily. The dose must be individualized by a qualified clinician. |
| Hepatic Impairment | No specific dose adjustment is recommended for hepatic impairment, but caution is advised. The dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum recommended daily dose of cefixime is 400 mg for adults. In children, the maximum dose is not established from available information. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cifigold dry syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Carbamazepine | Major | |
| Antacids | Moderate | |
| Iron supplements | Moderate | |
| Probenecid | Minor |
🚨 Major Interactions
- Warfarin
- Carbamazepine
⚡ Moderate Interactions
- Antacids (aluminum or magnesium hydroxide)
- Iron supplements
🍷 Alcohol Interaction
Alcohol does not directly interact with cefixime, but it may worsen stomach upset and dizziness. It is advisable to avoid alcohol while taking this medicine, especially if you have an infection.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to cefixime or other cephalosporins","History of severe allergic reaction to penicillins","Use in patients with carnitine deficiency (due to lactobacillus component? Not established)"]
⚠️ Warnings & Precautions
["Before starting this medicine, tell your doctor if you are allergic to penicillin or other antibiotics.","Use with caution in patients with kidney disease; dose adjustment may be needed.","Prolonged use may lead to overgrowth of non-susceptible organisms, including fungi.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Do not use this medicine to treat viral infections like the common cold.","Shake well before use and measure dose accurately.","Keep out of reach of children."]
🤱 Lactation Safety
Cefixime is excreted in human breast milk in low concentrations. It is generally considered safe during breastfeeding, but consult your doctor to weigh the benefits and risks. Monitor the infant for diarrhea or thrush.
💊 Overdose Management
If you suspect an overdose, seek emergency medical attention immediately. Symptoms of overdose may include nausea, vomiting, stomach pain, and diarrhea. Treatment is supportive and symptomatic. Hemodialysis may be considered in severe cases, but cefixime is not significantly removed by dialysis.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Shake the bottle well before each use to ensure the medicine is evenly mixed. Use a measuring spoon or cup to get the correct dose. Do not skip doses or stop early, even if you feel better. Complete the full course to prevent the infection from returning. Inform your doctor if you have kidney disease, stomach problems, or allergies to antibiotics. Avoid taking antacids or iron supplements within two hours of this medicine, as they can reduce its absorption. Store the suspension in the refrigerator and discard any unused portion after 14 days.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have reduced kidney function and may require a lower dose. They are also more susceptible to antibiotic-associated diarrhea and C. difficile infection. Monitor closely for side effects.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Cefixime is generally considered safe in pregnancy when prescribed by a doctor, but the benefits and risks should be weighed.
🏥 Post-Surgery Considerations
If you are scheduled for surgery, inform your surgeon that you are taking this medicine. It may interact with other medications used during surgery. Your surgeon may advise you to stop or adjust the dose.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It may interact with other medications or affect healing. Your dentist may recommend postponing non-urgent procedures until you complete the course.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
If you have a fever or feel weak, avoid strenuous exercise. Light activity like walking is fine if you feel up to it. Listen to your body and rest when needed.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or headache in some people. If you experience these, avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal activities, but rest is important for recovery.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can lead to recurrence of infection and antibiotic resistance. If you experience severe side effects, contact your doctor immediately; they may advise you to stop.
📅 Long-Term Use Effects
Long-term use of cefixime may lead to antibiotic resistance and disruption of gut flora. It is not intended for prolonged use unless prescribed for a specific chronic infection. Prolonged use may increase the risk of superinfection with resistant bacteria or fungi. Regular monitoring of renal and liver function may be needed if used for extended periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help prevent antibiotic-associated diarrhea when taken alongside antibiotics.
Evidence: Well-establishedFor viral infections, rest, fluids, and over-the-counter remedies are appropriate.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Antibiotics do not interfere with vaccines. However, if you are acutely ill with a fever, it may be better to postpone vaccination until you recover. Consult your doctor.
📦 Storage Guide
✅ DO
Store dry powder at room temperature (15-30°C)
❌ DON'T
Do not freeze the dry powder
✅ DO
After reconstitution, store in refrigerator (2-8°C)
❌ DON'T
Do not leave reconstituted suspension at room temperature for more than 1 hour
✅ DO
Keep in original container with cap tightly closed
❌ DON'T
Do not transfer to another container
✅ DO
Discard unused suspension after 14 days
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging with the prescription label. Keep the reconstituted suspension in a cool place, preferably a refrigerator. If refrigeration is not available, use a cooler bag with ice packs. Carry a copy of your prescription to avoid issues at customs. If crossing time zones, continue taking the medicine at the same intervals as prescribed. Do not leave the medicine in a hot car.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 24 to 48 hours, but it is important to complete the full course as prescribed.
A: Yes, you can take it with or without food. If it upsets your stomach, take it with a meal or snack.
A: Take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: Avoid taking antacids or iron supplements within 2 hours of this medicine. No other specific food restrictions.
A: No, you must complete the full course to prevent the infection from returning and to avoid antibiotic resistance.
🤔 Common Patient Concerns
🔄 Substitutes for cifigold dry syrup
View AllAlternative brands with exact same active ingredient:
-
refixim syrupRaphael Pharmaceuticals Pvt Ltd ₹33.75 19.6% CHEAPER
-
cefilite dry syrupLitaka Pharmaceuticals Ltd ₹39.62 5.7% CHEAPER
-
lococef lb 50mg dry syrupLoco Healthcare Pvt Ltd ₹41.04 2.3% CHEAPER
-
ceemi 50mg/60million spores tabletWinsome Laboratories Pvt Ltd ₹41.35 1.5% CHEAPER
-
cefxi o dry syrupMedley Pharmaceuticals ₹42.19 0.5% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure viral infections like the flu.
Fact: This medicine is an antibiotic and is only effective against bacterial infections. It does not treat viral infections. - Myth: You can stop taking this medicine once you feel better.
Fact: You must complete the full course as prescribed to prevent the infection from returning and to avoid antibiotic resistance.
🔄 Alternative Options
Generic Alternatives
- Cefixime + Lactobacillus oral suspension
Brand Alternatives
- Bronfix LB Oral Suspension Orange