Accuzon 125mg Injection: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or shortness of breath
- Swelling of the face, lips, tongue, or throat
- Severe or bloody diarrhea
- Unusual bruising or bleeding
- Yellowing of the skin or eyes
- Severe abdominal pain
- Decreased urine output
- Seizures or convulsions
- Rapid heartbeat or fainting
If experiencing severe symptoms, call emergency services immediately.
What is cefta one 125mg injection used for?
This medicine is an intravenous antibiotic containing Ceftriaxone 125mg. It is used to treat serious bacterial infections such as pneumonia, meningitis, and urinary tract infections. It works by killing bacteria and must be given by a healthcare professional.
- Generic Name: Ceftriaxone
- Manufacturer: Avita Laboratories Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cefta one 125mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा सेफ्ट्रिएक्सोन 125mg इंजेक्शन है, जिसका उपयोग बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है। यह निमोनिया, मेनिनजाइटिस, मूत्र मार्ग संक्रमण, त्वचा संक्रमण, और गोनोरिया जैसी बीमारियों में प्रभावी है। यह दवा बैक्टीरिया की कोशिका भित्ति को तोड़कर उन्हें मार देती है। यह केवल डॉक्टर या नर्स द्वारा अस्पताल में ही दी जाती है। इसे स्वयं न लगाएं।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन स्थल पर दर्द, लालिमा, दस्त, मतली, उल्टी और त्वचा पर चकत्ते शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, गंभीर दस्त, रक्त विकार, और यकृत एंजाइम में वृद्धि हो सकती है। यदि सांस लेने में कठिनाई, चेहरे या गले में सूजन, या गंभीर दस्त हो तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल योग्य स्वास्थ्य पेशेवर द्वारा ही दी जानी चाहिए। इसे स्वयं न लगाएं। इससे पहले कि आपको यह इंजेक्शन दिया जाए, अपने डॉक्टर को अपनी सभी एलर्जी और दवाओं के बारे में बताएं। यदि आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें। इलाज के दौरान शराब न पिएं। पूरा कोर्स पूरा करें, भले ही आप बेहतर महसूस करें। किसी भी नए लक्षण की तुरंत रिपोर्ट करें।
💊 cefta one 125mg injection Uses & Benefits
[{"condition":"Community-acquired pneumonia","description":"Used to treat bacterial pneumonia caused by susceptible organisms such as Streptococcus pneumoniae and Haemophilus influenzae.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"Effective against complicated and uncomplicated urinary tract infections caused by susceptible Gram-negative bacteria.","evidence":"Well-established"},{"condition":"Bacterial meningitis","description":"Used as part of initial therapy for bacterial meningitis in adults and children, often in combination with other antibiotics.","evidence":"Well-established"},{"condition":"Gonorrhea","description":"First-line treatment for uncomplicated gonorrhea caused by Neisseria gonorrhoeae.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Treats cellulitis, abscesses, and wound infections caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Septicemia","description":"Used in the management of bloodstream infections caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Intra-abdominal infections","description":"Used in combination with other antibiotics for complicated intra-abdominal infections.","evidence":"Well-established"},{"condition":"Bone and joint infections","description":"May be used for osteomyelitis and septic arthritis caused by susceptible bacteria.","evidence":"Established"}]
Off-label uses: [{"condition":"Lyme disease","description":"Sometimes used off-label for early disseminated Lyme disease, though other antibiotics are preferred.","evidence":"Limited"},{"condition":"Typhoid fever","description":"May be used off-label in areas where resistance patterns allow, but fluoroquinolones are often preferred.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Pneumonia, Urinary tract infections, Meningitis, Gonorrhea, Skin infections, Septicemia, Intra-abdominal infections, Bone and joint infections
📋 Drug Information
| Generic Name(s) | Ceftriaxone |
| Brand Name | Accuzon 1g Injection |
| Manufacturer | Avita Laboratories Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporins: 3 generation |
| Route of Administration | Intravenous (IV) administration only. It can be given as a direct IV injection over 2 to 4 minutes or as an IV infusion over 30 minutes. It should not be administered intramuscularly unless specifically formulated for that route |
| Storage | Store this medicine at room temperature, between 20°C and 25°C (68°F to 77°F). Protect from light and moisture. Keep the vial in its original carton until use. Do not freeze. Once reconstituted, the solution should be used within the time specified by the manufacturer, typically within 24 hours if stored at room temperature or 72 hours if refrigerated. Follow the specific instructions provided with the product. |
| Shelf Life | The shelf life of this medicine is typically 24 to 36 months from the date of manufacture, depending on the specific product and storage conditions. Always check the expiration date on the vial before use. Do not use if the solution is discolored or contains particulate matter. |
| WHO Guideline | The World Health Organization (WHO) includes ceftriaxone in its Model List of Essential Medicines. It is recommended for the treatment of several infections, including gonorrhea, meningitis, and pneumonia, based on local resistance patterns. Always follow national guidelines and local antibiograms. |
| ICMR Guideline | The Indian Council of Medical Research (ICMR) recommends ceftriaxone for the treatment of various bacterial infections, including community-acquired pneumonia, meningitis, and enteric fever, based on susceptibility patterns. It is important to use antibiotics judiciously and based on culture and sensitivity reports when possible. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by inhibiting bacterial cell wall synthesis. It binds to specific penicillin-binding proteins located inside the bacterial cell wall, which prevents the cross-linking of peptidoglycan strands. Without proper cross-linking, the bacterial cell wall becomes weak and cannot withstand the internal osmotic pressure, leading to cell lysis and death. This medicine is bactericidal, meaning it actively kills bacteria rather than just stopping their growth. It is effective against a broad spectrum of Gram-positive and Gram-negative bacteria, but it is not active against methicillin-resistant Staphylococcus aureus, Enterococcus species, or Pseudomonas aeruginosa.
Mechanism Steps
💡 How to Take cefta one 125mg injection
Strength: This medicine is available as a sterile powder for injection in a 125mg strength. It is reconstituted with a suitable diluent before intravenous administration. The 125mg strength is typically used for pediatric patients or for specific indications requiring lower doses.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine ranges from 1 to 2 grams once daily, or in divided doses every 12 hours, depending on the type and severity of the infection. For uncomplicated gonorrhea, a single 250 mg intramuscular dose is standard, but intravenous dosing may be used. For meningitis, doses up to 2 grams every 12 hours may be used. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-administer; this medicine must be given by a healthcare professional. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. In general, ceftriaxone may be used in children at doses of 50 to 75 mg/kg per day, but the exact dose depends on the infection, age, and weight. Neonates require special consideration due to the risk of kernicterus and calcium precipitation. Always consult a pediatrician for appropriate dosing. |
| Elderly Dosage | Elderly patients (above 65 years) may have reduced renal function, which can affect the elimination of this medicine. Dosage adjustment may be necessary based on creatinine clearance. Monitor renal function closely. No specific dose adjustments are recommended solely based on age, but individualization is important. |
| Renal Impairment | In patients with renal impairment, dosage adjustment is not usually required for ceftriaxone unless the impairment is severe (creatinine clearance less than 10 mL/min). In such cases, the dose may need to be reduced or the dosing interval extended. Monitor renal function and adjust as needed. Ceftriaxone is not removed by dialysis, so no supplemental dose is needed after dialysis. |
| Hepatic Impairment | In patients with hepatic impairment, dosage adjustment is generally not necessary unless there is concurrent renal impairment. In patients with both hepatic and renal impairment, the dose should be reduced and monitored closely. Consult a clinician for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose of this medicine is 4 grams per day, but doses up to 2 grams every 12 hours (4 grams per day) may be used for serious infections like meningitis. Doses above 4 grams per day are not recommended. Always follow your doctor's prescription. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cefta one 125mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Calcium-containing IV solutions | Major | |
| Warfarin | Major | |
| Aminoglycosides | Moderate | |
| Loop diuretics | Moderate | |
| Probenecid | Moderate | |
| Oral contraceptives | Moderate | |
| Chloramphenicol | Moderate | |
| Heparin | Minor | |
| Antacids | Minor | |
| Iron supplements | Minor |
🚨 Major Interactions
- Calcium-containing intravenous solutions (e.g., Ringer's solution, Hartmann's solution)
- Warfarin
- Other antibiotics (e.g., chloramphenicol, aminoglycosides)
⚡ Moderate Interactions
- Loop diuretics (e.g., furosemide)
- Probenecid
- Oral contraceptives
🍷 Alcohol Interaction
It is advisable to avoid alcohol while receiving this medicine. Alcohol can increase the risk of liver enzyme elevations, nausea, and dizziness. It may also worsen the underlying infection and delay recovery. Always consult your doctor about safe alcohol consumption during treatment.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity or severe allergic reaction to ceftriaxone, any other cephalosporin, or penicillin.","Neonates (up to 28 days of age) who are receiving intravenous calcium-containing solutions.","Neonates with hyperbilirubinemia or jaundice, as ceftriaxone can displace bilirubin and cause kernicterus.","Use in patients with a history of anaphylaxis to beta-lactam antibiotics.","Concurrent use with calcium-containing IV solutions in neonates."]
⚠️ Warnings & Precautions
["Serious and occasionally fatal hypersensitivity reactions, including anaphylaxis, can occur. Before starting therapy, inquire about previous hypersensitivity to penicillins, cephalosporins, or other allergens.","Clostridium difficile-associated diarrhea (CDAD) has been reported. If diarrhea develops, evaluate for CDAD. Mild cases may resolve with discontinuation; severe cases require appropriate treatment.","Use with caution in patients with a history of gastrointestinal disease, especially colitis.","May cause gallbladder sludge or stones, particularly in children. This is usually reversible after discontinuation.","Hematologic effects such as neutropenia, thrombocytopenia, and eosinophilia have been reported. Monitor blood counts during prolonged therapy.","May cause seizures, especially in patients with renal impairment or underlying CNS disorders. Use with caution.","Do not mix ceftriaxone with calcium-containing solutions or other drugs in the same IV line.","Prolonged use may result in overgrowth of nonsusceptible organisms, including fungi. Monitor for superinfection.","In patients with both renal and hepatic impairment, dosage adjustment may be necessary. Monitor drug levels if available."]
🤱 Lactation Safety
This medicine is excreted in human breast milk in low concentrations. It is generally considered safe during breastfeeding, but caution is advised. Consult your doctor to weigh the benefits of breastfeeding against the potential risks to the infant. If you notice any signs of thrush, diarrhea, or rash in your baby, contact your pediatrician.
💊 Overdose Management
Overdose of this medicine is unlikely due to its intravenous route of administration in a clinical setting. If overdose is suspected, treatment should be symptomatic and supportive. Ceftriaxone is not removed by hemodialysis or peritoneal dialysis. Monitor vital signs and provide supportive care. Contact a poison control center for guidance.
⏰ Missed Dose
This medicine is administered by a healthcare professional, so missed doses are unlikely. If you miss a scheduled dose, contact your doctor or nurse as soon as possible. Do not attempt to self-administer a double dose. Your healthcare provider will determine the appropriate timing for the next dose.
Additional Safety Advice
This medicine must be given only by a qualified healthcare professional in a clinical setting. Do not attempt to administer it yourself. Before receiving this injection, tell your doctor if you are allergic to penicillin, cephalosporins, or any other antibiotics. Inform your doctor about all other medicines you are taking, especially blood thinners, calcium-containing IV solutions, and other antibiotics. If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits with your doctor. Do not breastfeed while receiving this medicine without medical advice. Avoid alcohol during treatment as it may worsen side effects. Complete the full course as prescribed, even if you feel better, to prevent the infection from returning. Report any new symptoms, especially severe diarrhea, rash, or breathing difficulties, to your doctor immediately.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have reduced kidney function, which can affect the elimination of this medicine. Dosage adjustment may be necessary based on creatinine clearance. Monitor renal function closely. Elderly patients are also at higher risk of Clostridium difficile-associated diarrhea and should be monitored for severe diarrhea. Falls and confusion may occur; ensure a safe environment.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss with your doctor before receiving this medicine. It is classified as Pregnancy Category B, meaning it is generally considered safe, but should be used only if clearly needed. If you become pregnant while on this medicine, inform your doctor immediately. There is no evidence that this medicine affects fertility.
🏥 Post-Surgery Considerations
This medicine is often used to prevent or treat surgical site infections. If you are scheduled for surgery, your doctor may prescribe it as a prophylactic antibiotic. After surgery, continue as directed. Monitor the surgical wound for signs of infection, such as redness, swelling, or discharge. Report any concerns to your surgeon.
🦷 Dental Procedures
If you are undergoing dental procedures, inform your dentist that you are receiving this medicine. It may be used prophylactically for certain dental procedures in patients at risk of infective endocarditis. However, routine use for dental prophylaxis is not recommended unless specifically indicated. Follow your dentist's and doctor's advice.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While receiving this medicine, you may feel tired or weak. Avoid strenuous exercise until you have recovered from the infection. Light activities like walking are fine if you feel up to it. If you experience dizziness or shortness of breath, stop and rest. Consult your doctor before resuming your regular exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is given in a hospital or clinic, so you may need to take time off work or arrange for transportation. You may experience fatigue, dizziness, or nausea, which can affect your ability to drive or operate machinery. Avoid driving until you know how the medicine affects you. Discuss your work schedule with your employer and plan for adequate rest.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Even if you feel better, you must complete the full course to ensure the infection is fully treated and to prevent resistance. If you experience serious side effects, your doctor may decide to stop the medicine and switch to an alternative. Always follow your healthcare provider's instructions.
📅 Long-Term Use Effects
Long-term use of this medicine is not common, as it is typically used for short courses. Prolonged use may lead to antibiotic resistance, superinfections (such as oral thrush or Clostridium difficile colitis), and rarely, blood disorders or liver enzyme elevations. Regular monitoring of blood counts and liver function may be required if therapy is extended. Always use antibiotics judiciously and only when prescribed.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
For mild infections, oral antibiotics may be used instead of intravenous therapy, but this depends on the severity and type of infection.
Evidence: Well-establishedDepending on the bacteria and resistance patterns, other antibiotics such as fluoroquinolones or macrolides may be used.
Evidence: Well-establishedRest, hydration, and fever control are important adjuncts to antibiotic therapy.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you are scheduled to receive a live vaccine, inform your doctor, as antibiotics may affect the immune response to certain vaccines. In general, antibiotics do not contraindicate vaccination, but it is best to discuss with your healthcare provider.
📦 Storage Guide
✅ DO
Store at room temperature (20-25°C)
❌ DON'T
Do not freeze the vial
✅ DO
Keep in the original carton to protect from light
❌ DON'T
Do not expose to direct sunlight
✅ DO
Use reconstituted solution within the recommended time
❌ DON'T
Do not use if the solution is discolored or contains particles
✅ DO
Keep out of reach of children
❌ DON'T
Do not store in the bathroom
✈️ Traveling with This Medicine
If you are traveling and need to receive this medicine, carry a copy of your prescription and a letter from your doctor explaining the medical necessity. This medicine is usually administered in a healthcare facility, so plan ahead to locate a clinic or hospital at your destination. Store the vial at room temperature, away from direct sunlight, and do not freeze. If you are carrying reconstituted solution, follow the storage instructions provided by your pharmacist. Be aware of customs regulations regarding injectable medicines and carry proper documentation.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working quickly after intravenous administration, but you may not feel better immediately. Improvement in symptoms usually occurs within 24 to 48 hours, depending on the infection.
A: No, this medicine must be given by a healthcare professional in a hospital or clinic setting. It is not for self-administration.
A: Report any side effects to your doctor or nurse immediately. Mild side effects like nausea or injection site pain may resolve on their own, but serious effects require prompt medical attention.
A: This medicine can be used in children, but the dose is determined by a pediatrician based on weight and the type of infection. It is not recommended for neonates with jaundice or those receiving calcium-containing IV solutions.
A: This medicine passes into breast milk in small amounts. It is generally considered safe, but consult your doctor to weigh the benefits and risks. Watch for any signs of thrush or diarrhea in your baby.
🤔 Common Patient Concerns
🔄 Substitutes for cefta one 125mg injection
View AllAlternative brands with exact same active ingredient:
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oframax 125mg injectionSun Pharmaceutical Industries Ltd ₹13.87 22.1% CHEAPER
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Retel 125mg InjectionMcastro Pharma ₹16.41 7.9% CHEAPER
-
ctx 125mg injectionShince Pharmaceuticals Pvt Ltd ₹16.88 5.2% CHEAPER
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keftra 125mg injectionIpca Laboratories Ltd ₹16.88 5.2% CHEAPER
-
afzone 125mg injectionAdmac Pharma Ltd ₹17.85 0.2% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Accuzon 125mg injection can cure viral infections like the flu.
Fact: This medicine is an antibiotic and is only effective against bacterial infections. It does not treat viral infections. - Myth: You can stop taking Accuzon 125mg injection as soon as you feel better.
Fact: You must complete the full course as prescribed to prevent the infection from returning and to avoid antibiotic resistance. - Myth: Accuzon 125mg injection is safe to self-administer at home.
Fact: This medicine must be given by a healthcare professional in a clinical setting due to the risk of serious allergic reactions and other complications. - Myth: Accuzon 125mg injection is safe to use during pregnancy without any risks.
Fact: It is classified as Pregnancy Category B, meaning it should be used only if clearly needed, as determined by a doctor.
🔄 Alternative Options
Generic Alternatives
- Ceftriaxone 125mg injection
Brand Alternatives
- Monocef 125mg injection
- Oframax 125mg injection
- Intacef 125mg injection
- Cefaxone 125mg injection