cefport-of tablet
What is cefport-of tablet used for?
Abixim O Tablet (Cefixime + Ofloxacin) is used to treat ANTI INFECTIVES. It contains Cefixime (200mg) + Ofloxacin (200mg), which Cefixime inhibits bacterial cell wall synthesis; Ofloxacin inhibits DNA gyrase a. Always consult your doctor before use. Take as prescribed.
- Generic Name: Cefixime + Ofloxacin
- Manufacturer: Rexit Pharmaceutical
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ cefport-of tablet Uses & Benefits
Respiratory tract infections, urinary tract infections, gastrointestinal infections, skin and soft tissue infections, sexually transmitted infections
Off-label uses: Typhoid fever, Leprosy, Brucellosis
๐ Drug Information
| Generic Name(s) | Cefixime + Ofloxacin |
| Brand Name | Abixim O Tablet |
| Manufacturer | Rexit Pharmaceutical |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Antibiotic (Cephalosporin + Fluoroquinolone) |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC, protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Cefixime inhibits bacterial cell wall synthesis; Ofloxacin inhibits DNA gyrase and topoisomerase IV
Mechanism Steps
๐ก How to Take cefport-of tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of cefport-of tablet
โ Common Side Effects
- Nausea
- Diarrhea
- Headache
- Dizziness
- Abdominal pain
- Vomiting
- Dyspepsia
๐จ Serious Side Effects
- Tendon rupture
- Peripheral neuropathy
- Severe allergic reactions
- Clostridium difficile colitis
- QT prolongation
- Seizures
- Hepatotoxicity
โ ๏ธ Rare Side Effects
- Blood dyscrasias
- Stevens-Johnson syndrome
- Toxic epidermal necrolysis
- Interstitial nephritis
- Anaphylaxis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Antidiabetic agents | Major | Hypoglycemia |
| NSAIDs | Major | Increased CNS stimulation and seizure risk |
| Theophylline | Major | Increased theophylline toxicity |
| Corticosteroids | Major | Increased risk of tendon rupture |
| Antacids | Moderate | Reduced absorption of ofloxacin |
| Iron supplements | Moderate | Reduced absorption of ofloxacin |
| Zinc supplements | Moderate | Reduced absorption of ofloxacin |
| Sucralfate | Moderate | Reduced absorption of ofloxacin |
| Probenecid | Moderate | Increased cefixime levels |
| Caffeine | Minor | Increased caffeine effects |
| Cyclosporine | Minor | Possible nephrotoxicity |
| Methotrexate | Minor | Increased methotrexate levels |
๐จ Major Interactions
- Warfarin
- Antidiabetic agents
- NSAIDs
- Theophylline
- Corticosteroids
โก Moderate Interactions
- Antacids
- Iron supplements
- Zinc supplements
- Sucralfate
- Probenecid
โน๏ธ Minor Interactions
- Caffeine
- Cyclosporine
- Methotrexate
๐ฝ๏ธ Food Interactions
Avoid dairy products, antacids, and iron supplements within 2-4 hours; food may delay absorption
๐ท Alcohol Interaction
Avoid alcohol; may increase CNS effects and hepatotoxicity risk
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to cephalosporins, fluoroquinolones, or any component; history of tendon disorders with fluoroquinolones; pregnancy (ofloxacin); children <18 years (ofloxacin)
๐ Monitoring Parameters
Renal function, hepatic function, blood glucose (in diabetics), signs of tendonitis, CNS effects, QT interval
๐คฑ Lactation Safety
Excreted in breast milk; use with caution
๐ Overdose Management
Supportive care; gastric lavage; monitor renal function and ECG
โฐ Missed Dose
Take as soon as remembered; skip if almost time for next dose; do not double dose
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Effective and reliable. Worked as expected.
Good quality medicine. Satisfied with the outcome.
Good quality medicine. Satisfied with the outcome.
Effective and reliable. Worked as expected.
Helpful and effective medicine as per my experience. Always consult a doctor.