cefovin-o tablet - Cefpodoxime Proxetil (200mg) + Ofloxacin (200mg) medicine

cefovin-o tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Asvins Lifecare ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 27, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 27, 2026

What is cefovin-o tablet used for?

Acepod O 200mg/200mg Tablet (Cefpodoxime Proxetil + Ofloxacin) is used to treat ANTI INFECTIVES. It contains Cefpodoxime Proxetil (200mg) + Ofloxacin (200mg), which Cefpodoxime inhibits bacterial cell wall synthesis; Ofloxacin inhibits DNA gyras. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Cefpodoxime Proxetil + Ofloxacin
  • Manufacturer: Asvins Lifecare
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š cefovin-o tablet Uses & Benefits

Respiratory tract infections, urinary tract infections, skin and soft tissue infections, sexually transmitted infections

Off-label uses: Prostatitis, Bone and joint infections

๐Ÿ“‹ Drug Information

Generic Name(s)Cefpodoxime Proxetil + Ofloxacin
Brand NameAcepod O 200mg/200mg Tablet
ManufacturerAsvins Lifecare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassCephalosporin + Fluoroquinolone
Route of AdministrationOral
StorageStore at 20-25ยฐC, protect from light and moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionWidely distributed in body tissues and fluids
Protein BindingCefpodoxime: 21-29%; Ofloxacin: 20-32%
MetabolismCefpodoxime: minimal; Ofloxacin: hepatic (10%)
Half-LifeCefpodoxime: 2-3 hours; Ofloxacin: 4-5 hours
ExcretionRenal (both)
BioavailabilityCefpodoxime: 50%; Ofloxacin: 98%
Onset of Action1-2 hours
Peak Plasma TimeCefpodoxime: 2-3 hours; Ofloxacin: 1-2 hours
Duration of Action12 hours

How It Works

Cefpodoxime inhibits bacterial cell wall synthesis; Ofloxacin inhibits DNA gyrase and topoisomerase IV

Mechanism Steps

1Cefpodoxime binds to PBPs, inhibiting transpeptidase and disrupting cell wall synthesis
2Ofloxacin inhibits DNA gyrase, preventing DNA supercoiling
3Ofloxacin inhibits topoisomerase IV, blocking DNA replication

๐Ÿ’ก How to Take cefovin-o tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of cefovin-o tablet

โœ… Common Side Effects

  • Nausea
  • Diarrhea
  • Headache
  • Dizziness
  • Vaginal candidiasis

๐Ÿšจ Serious Side Effects

  • Pseudomembranous colitis
  • Tendon rupture
  • Peripheral neuropathy
  • QT prolongation
  • Seizures

โš ๏ธ Rare Side Effects

  • Hemolytic anemia
  • Stevens-Johnson syndrome
  • Toxic epidermal necrolysis
  • Interstitial nephritis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Antidiabetic agents Major Hypoglycemia
NSAIDs Major Increased CNS stimulation risk
Theophylline Major Increased theophylline toxicity
Corticosteroids Major Increased risk of tendon rupture
Probenecid Moderate Decreased renal excretion of cefpodoxime
Antacids Moderate Decreased absorption of ofloxacin
Iron supplements Moderate Decreased absorption of ofloxacin
Zinc supplements Moderate Decreased absorption of ofloxacin
Sucralfate Moderate Decreased absorption of ofloxacin
Cimetidine Minor Possible increased ofloxacin levels
Ranitidine Minor Possible increased ofloxacin levels

๐Ÿšจ Major Interactions

  • Warfarin
  • Antidiabetic agents
  • NSAIDs
  • Theophylline
  • Corticosteroids

โšก Moderate Interactions

  • Probenecid
  • Antacids
  • Iron supplements
  • Zinc supplements
  • Sucralfate

โ„น๏ธ Minor Interactions

  • Cimetidine
  • Ranitidine

๐Ÿฝ๏ธ Food Interactions

Dairy products, Calcium-fortified foods

๐Ÿท Alcohol Interaction

Avoid alcohol; may increase CNS effects

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to cephalosporins, fluoroquinolones, or any component; history of tendinopathy with fluoroquinolones; children <18 years (for ofloxacin)

๐Ÿ“Š Monitoring Parameters

Renal function, liver function, blood glucose, signs of superinfection, tendon pain

๐Ÿคฑ Lactation Safety

Excreted in breast milk; use with caution

๐Ÿ’Š Overdose Management

Supportive care; gastric lavage; monitor renal function and ECG

โฐ Missed Dose

Take as soon as remembered; skip if almost time for next dose; do not double

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 27, 2026

๐Ÿ”— View Profile

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