cefoclox xl tablet - Uses, Price, Side Effects & Substitutes
What is cefoclox xl tablet used for?
Acef LB (Cefpodoxime Proxetil + Lactobacillus) is used to treat ANTI INFECTIVES. It contains Cefpodoxime Proxetil (200mg) + Lactobacillus (500mg), which Cefpodoxime inhibits bacterial cell wall synthesis by binding to penicillin-bind. Always consult your doctor before use. Take as prescribed.
- Generic Name: Cefpodoxime Proxetil + Lactobacillus
- Manufacturer: Khandelwal Laboratories Pvt Ltd
- Form: Allopathy
- Pregnancy Category: B
- Prescription Required: Yes
๐ cefoclox xl tablet Uses & Benefits
Respiratory tract infections, urinary tract infections, skin and soft tissue infections, otitis media, sinusitis, and to prevent antibiotic-associated diarrhea.
Off-label uses: Prophylaxis of recurrent urinary tract infections, Treatment of Lyme disease
๐ Drug Information
| Generic Name(s) | Cefpodoxime Proxetil + Lactobacillus |
| Brand Name | Acef LB |
| Manufacturer | Khandelwal Laboratories Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporin antibiotic + Probiotic |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Cefpodoxime inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), inhibiting transpeptidation and autolysin inhibition. Lactobacillus restores intestinal flora.
Mechanism Steps
๐ก How to Take cefoclox xl tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of cefoclox xl tablet
โ Common Side Effects
- Diarrhea
- Nausea
- Vomiting
- Abdominal pain
- Headache
- Vaginal candidiasis
๐จ Serious Side Effects
- Pseudomembranous colitis
- Severe allergic reactions (anaphylaxis)
- Stevens-Johnson syndrome
- Seizures
- Hemolytic anemia
โ ๏ธ Rare Side Effects
- Hepatitis
- Interstitial nephritis
- Thrombocytopenia
- Agranulocytosis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased INR and bleeding risk |
| Probenecid | Major | Decreased renal excretion of cefpodoxime, increased toxicity |
| Live typhoid vaccine | Major | Reduced vaccine efficacy |
| BCG vaccine | Major | Reduced vaccine efficacy |
| Loop diuretics | Moderate | Increased nephrotoxicity risk |
| Aminoglycosides | Moderate | Increased nephrotoxicity risk |
| Oral contraceptives | Moderate | Reduced contraceptive efficacy |
| Antacids | Minor | Decreased absorption of cefpodoxime |
| H2 antagonists | Minor | Decreased absorption of cefpodoxime |
| Iron supplements | Minor | Decreased absorption of cefpodoxime |
๐จ Major Interactions
- Warfarin
- Probenecid
- Live typhoid vaccine
- BCG vaccine
โก Moderate Interactions
- Loop diuretics
- Aminoglycosides
- Oral contraceptives
โน๏ธ Minor Interactions
- Antacids
- H2 antagonists
- Iron supplements
๐ฝ๏ธ Food Interactions
Food increases absorption of cefpodoxime
๐ท Alcohol Interaction
No known interaction, but alcohol may increase side effects like dizziness.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to cephalosporins or penicillins; severe renal impairment (CrCl <30 mL/min) without dose adjustment.
๐ Monitoring Parameters
Renal function, signs of superinfection, diarrhea, allergic reactions.
๐คฑ Lactation Safety
Cefpodoxime is excreted in breast milk in low amounts; use with caution.
๐ Overdose Management
Supportive care; hemodialysis may enhance elimination.
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.