cefluv 50mg/20million spores tablet dt - Cefixime (50mg) + Lactobacillus (20Million spores) medicine

cefluv 50mg/20million spores tablet dt

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🏭 Wisdom Pharma Pvt. Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

What is cefluv 50mg/20million spores tablet dt used for?

This medicine contains Cefixime (50mg) + Lactobacillus (20Million spores) and is used to treat ANTI INFECTIVES. Cefixime inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). La. Always consult your doctor before use.

  • Generic Name: Cefixime + Lactobacillus
  • Manufacturer: Wisdom Pharma Pvt. Ltd
  • Form: Allopathy
  • Pregnancy Category: Category A
  • Prescription Required: Yes
💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 cefluv 50mg/20million spores tablet dt Uses & Benefits

Upper respiratory tract infections, lower respiratory tract infections, urinary tract infections, otitis media, gonorrhea, typhoid fever.

Off-label uses: Prophylaxis in surgery, Lyme disease, Shigellosis

📋 Drug Information

Generic Name(s)Cefixime + Lactobacillus
Brand NameAfix 200mg Tablet
ManufacturerWisdom Pharma Pvt. Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassThird-generation cephalosporin antibiotic + Probiotic
Route of AdministrationOral
StorageStore at 20-25°C (68-77°F); protect from light and moisture.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionCefixime is well absorbed orally; food does not affect absorption. Lactobacillus is not absorbed.
DistributionCefixime distributes widely into tissues and fluids; crosses placenta; minimal CSF penetration. Lactobacillus remains in GI tract.
Protein BindingCefixime: ~65% bound to plasma proteins. Lactobacillus: not applicable.
MetabolismCefixime: minimal hepatic metabolism. Lactobacillus: not metabolized.
Half-LifeCefixime: 3-4 hours (prolonged in renal impairment). Lactobacillus: not applicable.
ExcretionCefixime: primarily renal (50-60% unchanged). Lactobacillus: excreted in feces.
BioavailabilityCefixime: ~40-50% oral bioavailability. Lactobacillus: not applicable.
Onset of ActionCefixime: 1-2 hours. Lactobacillus: not applicable.
Peak Plasma TimeCefixime: 2-6 hours. Lactobacillus: not applicable.
Duration of ActionCefixime: 12-24 hours. Lactobacillus: not applicable.

How It Works

Cefixime inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). Lactobacillus restores gut flora.

Mechanism Steps

1Cefixime binds to penicillin-binding proteins (PBPs) on bacterial cell wall.
2Inhibits transpeptidase enzymes, preventing cross-linking of peptidoglycan.
3Activates autolytic enzymes, leading to cell lysis and death.
4Lactobacillus produces lactic acid, lowering pH and inhibiting pathogen growth.
5Lactobacillus competes with pathogens for adhesion sites and nutrients.
6Lactobacillus modulates immune response and restores gut microbiota balance.

💡 How to Take cefluv 50mg/20million spores tablet dt

Follow your doctor's prescription exactly.

⚠️ Side Effects of cefluv 50mg/20million spores tablet dt

✅ Common Side Effects

Diarrhea
Nausea
Vomiting
Abdominal pain
Headache
Dizziness
Rash

🚨 Serious Side Effects

Pseudomembranous colitis
Severe allergic reactions (anaphylaxis)
Stevens-Johnson syndrome
Seizures
Hemolytic anemia

⚠️ Rare Side Effects

Hepatitis
Interstitial nephritis
Thrombocytopenia
Agranulocytosis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major Increased bleeding risk
Probenecid Major Decreased renal excretion of cefixime, increased toxicity
Live typhoid vaccine Major Reduced vaccine efficacy
BCG vaccine Moderate Reduced vaccine efficacy
Cholera vaccine Moderate Reduced vaccine efficacy
Oral contraceptives Moderate Reduced contraceptive efficacy
Antacids Minor Possible reduced absorption of cefixime
Iron supplements Minor Possible reduced absorption
Zinc supplements Minor Possible reduced absorption

🚨 Major Interactions

  • Warfarin
  • Probenecid
  • Live typhoid vaccine

⚡ Moderate Interactions

  • BCG vaccine
  • Cholera vaccine
  • Oral contraceptives

🍷 Alcohol Interaction

Avoid alcohol; may increase risk of disulfiram-like reaction (rare).

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to cephalosporins or penicillins; severe renal impairment (CrCl

🤱 Lactation Safety

Cefixime excreted in breast milk in low amounts; caution. Lactobacillus considered safe.

💊 Overdose Management

Supportive care; hemodialysis may remove cefixime.

⏰ Missed Dose

Take as soon as remembered; skip if almost time for next dose; do not double.

🔄 Substitutes for cefluv 50mg/20million spores tablet dt

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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