cefi x l 100mg tablet - Cefixime (100mg) + Cloxacillin (500mg) medicine

cefi x l 100mg tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Swiss Pharma Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 30, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 30, 2026

What is cefi x l 100mg tablet used for?

Bioxim XL 200mg/500mg Tablet (Cefixime + Cloxacillin) is used to treat ANTI INFECTIVES. It contains Cefixime (100mg) + Cloxacillin (500mg), which Cefixime inhibits bacterial cell wall synthesis by binding to penicillin-binding. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Cefixime + Cloxacillin
  • Manufacturer: Swiss Pharma Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: B
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š cefi x l 100mg tablet Uses & Benefits

Respiratory tract infections, urinary tract infections, skin and soft tissue infections, bone and joint infections

Off-label uses: Prophylaxis in surgery, Lyme disease

๐Ÿ“‹ Drug Information

Generic Name(s)Cefixime + Cloxacillin
Brand NameBioxim XL 200mg/500mg Tablet
ManufacturerSwiss Pharma Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassCephalosporin + Penicillinase-resistant penicillin
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture and light
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from gastrointestinal tract
DistributionDistributes widely into body tissues and fluids
Protein BindingCefixime: 65%; Cloxacillin: 90-95%
MetabolismCefixime: minimally metabolized; Cloxacillin: hepatic
Half-LifeCefixime: 3-4 hours; Cloxacillin: 0.5-1 hour
ExcretionCefixime: renal (biliary); Cloxacillin: renal and biliary
BioavailabilityCefixime: 40-50%; Cloxacillin: 50-70%
Onset of Action1-2 hours
Peak Plasma TimeCefixime: 4 hours; Cloxacillin: 1-2 hours
Duration of Action12 hours

How It Works

Cefixime inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins; Cloxacillin inhibits bacterial cell wall synthesis and is resistant to beta-lactamases

Mechanism Steps

1Cefixime binds to penicillin-binding proteins (PBPs) on bacterial cell wall
2Inhibits transpeptidase activity, preventing cross-linking of peptidoglycan
3Activates autolytic enzymes, leading to cell lysis and death

๐Ÿ’ก How to Take cefi x l 100mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of cefi x l 100mg tablet

โœ… Common Side Effects

  • Diarrhea
  • Nausea
  • Vomiting
  • Abdominal pain
  • Rash

๐Ÿšจ Serious Side Effects

  • Pseudomembranous colitis
  • Anaphylaxis
  • Stevens-Johnson syndrome
  • Seizures

โš ๏ธ Rare Side Effects

  • Hemolytic anemia
  • Interstitial nephritis
  • Hepatitis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Methotrexate Major Increased methotrexate toxicity
Probenecid Major Decreased renal excretion of cephalosporins
Oral contraceptives Moderate Reduced contraceptive efficacy
Live typhoid vaccine Moderate Reduced vaccine efficacy
BCG vaccine Moderate Reduced vaccine efficacy
Antacids Minor Reduced absorption of cefixime
Iron supplements Minor Reduced absorption of cefixime

๐Ÿšจ Major Interactions

  • Warfarin
  • Methotrexate
  • Probenecid

โšก Moderate Interactions

  • Oral contraceptives
  • Live typhoid vaccine
  • BCG vaccine

โ„น๏ธ Minor Interactions

  • Antacids
  • Iron supplements

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption; take on empty stomach

๐Ÿท Alcohol Interaction

Avoid alcohol; may cause disulfiram-like reaction

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to cephalosporins or penicillins, history of anaphylaxis

๐Ÿ“Š Monitoring Parameters

Renal function, hepatic function, CBC, signs of superinfection

๐Ÿคฑ Lactation Safety

Excreted in breast milk; use with caution

๐Ÿ’Š Overdose Management

Supportive care; hemodialysis may be considered

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 30, 2026

๐Ÿ”— View Profile

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