Abixim Drop (Cefixime 25mg): Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swallowing
- Swelling of the face, lips, tongue, or throat
- Severe or persistent diarrhea, which may contain blood or mucus
- Signs of a severe skin reaction such as rash with blisters or peeling skin
- Yellowing of the skin or eyes (jaundice)
- Decreased urine output or swelling in the legs or feet
- Unusual bleeding or bruising
- Seizures or severe dizziness
If experiencing severe symptoms, call emergency services immediately.
What is ceffo drop used for?
This medicine is an oral antibiotic containing Cefixime, used to treat bacterial infections in children and adults. It works by killing bacteria and is available as a 25 mg drop formulation for easy administration.
- Generic Name: Cefixime
- Manufacturer: MRG Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 ceffo drop के बारे में (Hindi Summary)
उपयोग: यह दवा सेफिक्साइम नामक एंटीबायोटिक है, जिसका उपयोग बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है। यह विशेष रूप से बच्चों में कान के संक्रमण, गले के संक्रमण, श्वसन तंत्र के संक्रमण और मूत्र मार्ग के संक्रमण के लिए दी जाती है। यह दवा बैक्टीरिया को मारकर काम करती है और ड्रॉप के रूप में उपलब्ध है, जिससे छोटे बच्चों को देना आसान होता है। इसका उपयोग डॉक्टर के परामर्श के बिना न करें।
साइड इफेक्ट्स: इस दवा के कुछ सामान्य दुष्प्रभाव हो सकते हैं जैसे दस्त, जी मिचलाना, पेट दर्द, उल्टी और सिरदर्द। ये आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। कभी-कभी गंभीर एलर्जी प्रतिक्रिया हो सकती है, जिसमें सांस लेने में कठिनाई, चेहरे या गले में सूजन शामिल है। अगर ऐसा हो तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी एलर्जी और दवाओं के बारे में बताएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। बच्चों को सही मात्रा में दवा दें और मापने के लिए दिए गए ड्रॉपर का ही उपयोग करें। दवा का कोर्स पूरा करें, बीच में न छोड़ें। दवा को ठंडी और सूखी जगह पर रखें।
💊 ceffo drop Uses & Benefits
[{"condition":"Acute otitis media","description":"This medicine is used to treat middle ear infections caused by susceptible bacteria such as Haemophilus influenzae, Moraxella catarrhalis, and Streptococcus pneumoniae.","evidence":"Well-established"},{"condition":"Upper respiratory tract infections","description":"It is prescribed for infections like pharyngitis and tonsillitis when caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"This medicine is effective against uncomplicated urinary tract infections caused by susceptible strains of Escherichia coli and Klebsiella species.","evidence":"Well-established"},{"condition":"Lower respiratory tract infections","description":"It may be used for bronchitis and pneumonia caused by susceptible bacteria, though it is not the first-line agent for all such infections.","evidence":"Moderate"},{"condition":"Gonorrhea","description":"This medicine is used as an alternative treatment for uncomplicated gonorrhea caused by Neisseria gonorrhoeae.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Prophylaxis in dental procedures","description":"Sometimes used off-label to prevent infection in certain dental procedures for patients at risk, but this is not a standard indication.","evidence":"Limited"},{"condition":"Traveler's diarrhea","description":"Occasionally prescribed off-label for traveler's diarrhea caused by susceptible bacteria, but fluoroquinolones are more commonly used.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Otitis media, Pharyngitis, Tonsillitis, Urinary tract infections, Bronchitis
📋 Drug Information
| Generic Name(s) | Cefixime |
| Brand Name | Abixim |
| Manufacturer | MRG Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporins: 3 generation |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep the bottle tightly closed. Do not freeze. After reconstitution, store as directed on the label, usually for a specified number of days in the refrigerator. |
| Shelf Life | The shelf life of this medicine is typically 2 years from the date of manufacture when stored as directed. After reconstitution, the shelf life is usually 7 to 14 days if stored in the refrigerator, as specified by the manufacturer. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by inhibiting bacterial cell wall synthesis. It binds to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, which are enzymes involved in the cross-linking of peptidoglycan chains. By inhibiting these enzymes, the medicine prevents the formation of a stable cell wall, leading to bacterial cell lysis and death. This medicine is bactericidal, meaning it kills the bacteria directly. It is effective against a wide range of gram-positive and gram-negative bacteria, although its spectrum is not as broad as some other third-generation cephalosporins. It is stable against many beta-lactamases, enzymes produced by some bacteria that can inactivate penicillins, which contributes to its effectiveness against certain resistant strains.
Mechanism Steps
💡 How to Take ceffo drop
Strength: This medicine is available as an oral drop formulation containing 25 mg of Cefixime per unit dose (e.g., per mL or per drop, as specified by the manufacturer). The exact concentration should be confirmed from the product label.
Dosage Information
| Adult Dosage | The adult dosage of this medicine is determined by the healthcare provider based on the type and severity of the infection, as well as the patient's renal function. Typically, for adults, the dose may range from 200 mg to 400 mg per day, divided into one or two doses. However, this drop formulation is primarily intended for pediatric use, and adult dosing may require a different formulation. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-medicate; follow your doctor's prescription exactly. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. The dosage for children is typically based on weight and the specific infection being treated. The drop formulation allows for precise dosing in infants and young children. The usual pediatric dose may range from 8 mg/kg/day to 20 mg/kg/day, but this must be determined by a pediatrician. Use the provided dropper to measure the dose accurately. Do not exceed the recommended dose. |
| Elderly Dosage | Elderly patients may have reduced renal function, which can affect the elimination of this medicine. Dose adjustment may be necessary based on renal function. The dose must be individualized by a qualified clinician. Elderly patients should be monitored for signs of toxicity and side effects. |
| Renal Impairment | In patients with renal impairment, the dose of this medicine should be adjusted based on creatinine clearance. For patients with a creatinine clearance of 20-40 mL/min, the dose may be reduced to 50% of the usual dose. For those with a creatinine clearance less than 20 mL/min, the dose may be reduced further or the dosing interval extended. The dose must be individualized by a qualified clinician based on renal function. |
| Hepatic Impairment | No specific dosage adjustment is provided for patients with hepatic impairment in the available information. However, since this medicine is not extensively metabolized by the liver, hepatic impairment is unlikely to significantly affect its elimination. The dose must be individualized by a qualified clinician based on hepatic function and clinical response. |
| Maximum Daily Dose | The maximum daily dose of this medicine for adults is typically 400 mg, but this may vary based on the indication and renal function. For children, the maximum daily dose is determined by weight and should not exceed the adult dose. The dose must be individualized by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of ceffo drop
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Carbamazepine | Major | |
| Probenecid | Moderate | |
| Oral contraceptives | Moderate | |
| Antacids | Minor | |
| Iron supplements | Minor |
🚨 Major Interactions
- Warfarin
- Carbamazepine
⚡ Moderate Interactions
- Probenecid
- Oral contraceptives
🍷 Alcohol Interaction
Alcohol may exacerbate certain side effects of this medicine, such as dizziness or gastrointestinal upset. It is advisable to avoid or limit alcohol consumption while taking this medicine, especially if you experience side effects. Additionally, alcohol can weaken the immune system and may interfere with recovery from infection.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to cefixime or any other cephalosporin antibiotic","Known allergy to penicillins (cross-reactivity may occur)","Previous history of severe allergic reaction to beta-lactam antibiotics"]
⚠️ Warnings & Precautions
["Use with caution in patients with renal impairment; dose adjustment may be necessary.","Use with caution in patients with a history of gastrointestinal disease, especially colitis.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Prolonged use may result in overgrowth of non-susceptible organisms, including fungi.","Do not use for viral infections; it is ineffective and may promote resistance.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Keep out of reach of children; store as directed."]
🤱 Lactation Safety
Cefixime is excreted in human breast milk in low concentrations. It is generally considered safe during breastfeeding, but consult your doctor to weigh the benefits and risks. Monitor the infant for diarrhea or thrush.
💊 Overdose Management
Overdose of this medicine may cause nausea, vomiting, abdominal pain, and diarrhea. In severe cases, it may lead to seizures or renal impairment. If you suspect an overdose, seek immediate medical attention. Treatment is symptomatic and supportive. Hemodialysis may be considered in severe cases, but it is not routinely used.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up. Try to take it at the same time each day to maintain consistent levels.
Additional Safety Advice
Before taking this medicine, inform your doctor if you are allergic to cefixime, other cephalosporins, or penicillins. Also, disclose any history of kidney disease, liver disease, or gastrointestinal problems, especially colitis. This medicine may interact with other medications, so provide a complete list of all medicines you are taking, including prescription, over-the-counter, and herbal products. Do not start or stop any medicine without your doctor's approval. If you are pregnant or breastfeeding, consult your doctor before using this medicine, as it may not be suitable for you. For children, the dose is usually based on weight and should be measured carefully using the provided dropper or measuring device. Do not use a kitchen spoon, as it may not give an accurate dose. Shake the bottle well before each use to ensure the medicine is evenly mixed. Store this medicine as directed on the label, and keep it out of reach of children. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up. If you experience any signs of a serious allergic reaction, seek emergency medical help immediately.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have reduced renal function, which can affect the elimination of this medicine. Dose adjustment may be necessary based on renal function. Elderly patients should be monitored for signs of toxicity and side effects. They may also be more susceptible to drug interactions due to multiple medications.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. It is classified as Pregnancy Category B, meaning it is generally considered safe, but should only be used if clearly needed. Discuss the risks and benefits with your healthcare provider.
🏥 Post-Surgery Considerations
If you are scheduled for surgery, inform your surgeon that you are taking this medicine. It may need to be stopped before certain procedures, or the surgeon may adjust other medications. This medicine is sometimes used to prevent infection after surgery, but only under medical supervision.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. It may interact with other medications used during dental procedures, or it may be prescribed as prophylaxis for certain dental work in patients at risk of infection. Do not stop taking this medicine without consulting your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
There are no specific exercise restrictions while taking this medicine, but if you or your child feels tired or unwell, rest is recommended. Avoid strenuous activities if experiencing dizziness or fatigue.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue in some individuals. If you experience these effects, avoid driving or operating heavy machinery until you know how the medicine affects you. Children can usually continue with normal activities as tolerated, but rest is important for recovery.
🛑 When to Stop This Medicine
Do not stop taking this medicine before completing the full course prescribed by your doctor, even if symptoms improve. Stopping early can lead to recurrence of the infection and antibiotic resistance. If you experience severe side effects, contact your doctor immediately for advice on whether to continue.
📅 Long-Term Use Effects
Long-term use of this medicine is not typically recommended unless for a specific chronic infection under specialist care. Prolonged use can lead to antibiotic resistance and may increase the risk of side effects such as gastrointestinal disturbances and fungal overgrowth. Regular monitoring of renal and hepatic function may be required if used for extended periods. Always consult your doctor before using this medicine for more than the prescribed duration.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help prevent antibiotic-associated diarrhea when taken alongside this medicine.
Evidence: ModerateFor symptom relief such as fever and pain, but do not treat the infection.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you or your child is scheduled for a live vaccine, inform the doctor, as antibiotics may affect the immune response to certain vaccines. Generally, antibiotics do not interfere with most vaccines.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging with the prescription label intact. Bring a copy of the prescription in case you need to show it at customs or if you need a refill. Keep the medicine in your carry-on luggage to avoid temperature extremes in checked baggage. If traveling across time zones, adjust the dosing schedule gradually, but consult your doctor for specific advice. Store the medicine at room temperature and protect it from light and moisture. If the medicine requires refrigeration after reconstitution, ensure you have access to a refrigerator at your destination.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start to see improvement in symptoms within 24 to 48 hours, but it is important to complete the full course as prescribed.
A: Yes, this medicine can be taken with or without food. Taking it with food may help reduce stomach upset.
A: If your child vomits within 30 minutes of taking the dose, consult your doctor or pharmacist for advice. Do not give another dose without guidance.
A: This medicine is used in infants under the guidance of a pediatrician. The dose is based on weight and the specific infection.
A: Diarrhea is a common side effect of antibiotics. It is usually mild and resolves after treatment. If it is severe or persistent, contact your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for ceffo drop
View AllAlternative brands with exact same active ingredient:
-
trixon-o dropLincoln Pharmaceuticals Ltd ₹36.84 6.4% CHEAPER
-
Topcef 25mg Oral DropsTorrent Pharmaceuticals Ltd ₹39.70 0.8% COSTLIER
-
hifen 25mg oral dropsHetero Drugs Ltd ₹41.81 6.2% COSTLIER
-
avoxime 25mg oral dropsAvonic Life Sciences ₹42.00 6.7% COSTLIER
-
cefidol oral dropsDolvis Bio Pharma Pvt Ltd ₹42.00 6.7% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Antibiotics can cure viral infections like the common cold.
Fact: This medicine is effective only against bacterial infections. It does not treat viral infections. - Myth: You can stop taking antibiotics once you feel better.
Fact: You must complete the full course as prescribed to prevent recurrence and resistance. - Myth: Antibiotics can be shared with others.
Fact: This medicine should only be taken by the person it was prescribed for.
🔄 Alternative Options
Generic Alternatives
- Cefixime oral drops 25 mg
Brand Alternatives
- Abixim drop