cefflo s 1000mg/500mg injection
What is cefflo s 1000mg/500mg injection used for?
This medicine contains Ceftriaxone (1000mg) + Sulbactam (500mg) and is used to treat ANTI INFECTIVES. Ceftriaxone inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs);. Always consult your doctor before use.
- Generic Name: Ceftriaxone + Sulbactam
- Manufacturer: Flora Biotech
- Form: Allopathy
- Pregnancy Category: Category A
- Prescription Required: Yes
💊 cefflo s 1000mg/500mg injection Uses & Benefits
Lower respiratory tract infections, urinary tract infections, skin and soft tissue infections, intra-abdominal infections, septicemia, meningitis, bone and joint infections
Off-label uses: Gonorrhea, Lyme disease, pelvic inflammatory disease
📋 Drug Information
| Generic Name(s) | Ceftriaxone + Sulbactam |
| Brand Name | Accuzon Plus 1.5gm Injection |
| Manufacturer | Flora Biotech |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporin + Beta-lactamase inhibitor |
| Route of Administration | Intravenous (IV) or Intramuscular (IM) |
| Storage | Store at 20-25°C (68-77°F); protect from light; reconstituted solution stable for 24 hours at room temperature or 3 days refrigerated |
| Shelf Life | As per manufacturer |
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Ceftriaxone inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs); Sulbactam irreversibly inhibits beta-lactamases, protecting ceftriaxone from degradation.
Mechanism Steps
💡 How to Take cefflo s 1000mg/500mg injection
Follow your doctor's prescription exactly.
⚠️ Side Effects of cefflo s 1000mg/500mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Alcohol | Major | Disulfiram-like reaction |
| Aminoglycosides | Major | Increased nephrotoxicity |
| Probenecid | Moderate | Decreased renal excretion of ceftriaxone |
| Loop diuretics | Moderate | Increased nephrotoxicity risk |
| NSAIDs | Moderate | Increased bleeding risk |
| Live vaccines | Minor | Reduced vaccine efficacy |
| BCG | Minor | Reduced therapeutic effect |
🚨 Major Interactions
- Warfarin
- Alcohol (disulfiram-like reaction)
- Aminoglycosides (nephrotoxicity)
⚡ Moderate Interactions
- Probenecid
- Loop diuretics
- NSAIDs
🍷 Alcohol Interaction
May cause disulfiram-like reaction (nausea, vomiting, headache)
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity to cephalosporins or beta-lactam antibiotics; history of anaphylaxis to penicillins
🤱 Lactation Safety
Excreted in breast milk in low amounts; generally considered compatible
💊 Overdose Management
Supportive care; hemodialysis may remove ceftriaxone but not sulbactam
⏰ Missed Dose
Administer as soon as remembered; if near next dose, skip missed dose; do not double dose
🔄 Substitutes for cefflo s 1000mg/500mg injection
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Medical Note: Always consult your doctor before switching medications.