Accutaz PS 250mg/31.25mg Injection: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of face, lips, or throat
- Severe or bloody diarrhea
- Rash with blisters or peeling skin
- Seizures or confusion
- Decreased urine output or swelling in legs
- Yellowing of eyes or skin
- Persistent high fever despite treatment
If experiencing severe symptoms, call emergency services immediately.
What is cefbact t 250 mg/31.25 mg injection used for?
This medicine is a combination antibiotic containing ceftriaxone and tazobactum, used intravenously to treat serious bacterial infections. It works by killing bacteria and overcoming resistance.
- Generic Name: Ceftriaxone + Tazobactam
- Manufacturer: Cipla Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cefbact t 250 mg/31.25 mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा सेफ्ट्रिएक्सोन और टैज़ोबैक्टम का संयोजन है, जिसका उपयोग गंभीर जीवाणु संक्रमणों के इलाज के लिए अंतःशिरा (IV) मार्ग से किया जाता है। यह मूत्र पथ, पेट, त्वचा और फेफड़ों के संक्रमण में प्रभावी है। यह केवल डॉक्टर की देखरेख में ही दी जानी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन स्थल पर दर्द, दस्त, मतली, उल्टी और त्वचा पर चकत्ते शामिल हैं। गंभीर दुष्प्रभावों में एलर्जी, गंभीर दस्त, और किडनी या लीवर की समस्या हो सकती है। किसी भी असामान्य लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल अस्पताल या क्लिनिक में डॉक्टर या नर्स द्वारा दी जानी चाहिए। अपनी सभी एलर्जी और दवाओं के बारे में डॉक्टर को बताएं। गुर्दे या लीवर की बीमारी में सावधानी बरतें। इलाज के दौरान शराब न पिएं। पूरा कोर्स पूरा करें।
💊 cefbact t 250 mg/31.25 mg injection Uses & Benefits
[{"condition":"Complicated urinary tract infections","description":"Used to treat serious kidney and bladder infections caused by susceptible bacteria, including those producing beta-lactamase enzymes.","evidence":"Well-established"},{"condition":"Intra-abdominal infections","description":"Effective against mixed aerobic and anaerobic bacteria in conditions like peritonitis and abscesses.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Treats severe cellulitis, abscesses, and wound infections caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Community-acquired pneumonia","description":"Used when resistant bacteria are suspected or in hospitalized patients requiring intravenous therapy.","evidence":"Well-established"},{"condition":"Bacterial meningitis","description":"Ceftriaxone component is effective against common meningeal pathogens; tazobactum extends coverage against resistant strains.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Lyme disease","description":"Sometimes used for severe or neurological Lyme disease when other treatments are not suitable.","evidence":"Limited"},{"condition":"Gonorrhea","description":"Ceftriaxone is a first-line treatment; tazobactum may be added for resistant cases, though not standard.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Urinary tract infections, Intra-abdominal infections, Skin infections, Pneumonia, Meningitis
📋 Drug Information
| Generic Name(s) | Ceftriaxone + Tazobactam |
| Brand Name | Accutaz AS |
| Manufacturer | Cipla Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Antibiotic (Cephalosporin + Beta-lactamase inhibitor) |
| Route of Administration | Intravenous (IV) only. This medicine must be administered by a qualified healthcare professional |
| Storage | Store the unreconstituted powder at room temperature (15-30°C) in a dry place, protected from light. After reconstitution, the solution should be used immediately or stored as per instructions (usually refrigerated and used within 24 hours). Do not freeze. |
| Shelf Life | 24 months from the date of manufacture for the powder. After reconstitution, use within the specified time as per the product insert. |
| WHO Guideline | Not established from the available information. Guidelines may recommend ceftriaxone-tazobactum for specific infections based on local resistance patterns. |
| ICMR Guideline | Not established from the available information. ICMR guidelines may include this combination for certain hospital-acquired infections. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by inhibiting bacterial cell wall synthesis. Ceftriaxone binds to penicillin-binding proteins (PBPs) and blocks the cross-linking of peptidoglycan, leading to bacterial lysis. Tazobactum is a beta-lactamase inhibitor that protects ceftriaxone from degradation by certain beta-lactamase enzymes produced by resistant bacteria, thereby extending its spectrum of activity.
Mechanism Steps
💡 How to Take cefbact t 250 mg/31.25 mg injection
Strength: Injection: Ceftriaxone 250 mg + Tazobactum 31.25 mg per vial.
Dosage Information
| Adult Dosage | The dose of this medicine must be individualized by a qualified clinician based on the type and severity of infection, patient age, weight, and renal function. Typical adult doses range from 250 mg to 2 g of ceftriaxone component every 24 hours, with tazobactum in a fixed ratio. For severe infections, higher doses may be used. Always follow the prescribed dose and duration. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing based on weight and infection type. |
| Elderly Dosage | Elderly patients may have reduced renal function; dose adjustment may be necessary. Monitor renal function closely and individualize dose as per clinician's judgment. |
| Renal Impairment | In patients with renal impairment, dose adjustment may be required. For creatinine clearance less than 10 mL/min, the daily dose of ceftriaxone should not exceed 2 g. Tazobactum dose may need reduction. Consult a clinician for specific guidance. |
| Hepatic Impairment | No specific dose adjustment is established for hepatic impairment alone. However, in patients with both hepatic and renal impairment, monitor closely and adjust dose as needed. |
| Maximum Daily Dose | The maximum daily dose should not exceed 4 g of ceftriaxone component, but this must be determined by a clinician based on the clinical situation. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cefbact t 250 mg/31.25 mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Calcium-containing IV solutions | Major | |
| Aminoglycosides | Moderate | |
| Loop diuretics | Moderate | |
| Probenecid | Minor |
🚨 Major Interactions
- Warfarin
- Calcium-containing intravenous solutions
⚡ Moderate Interactions
- Aminoglycosides
- Loop diuretics
🍷 Alcohol Interaction
Avoid alcohol consumption during treatment with this medicine as it may worsen side effects such as nausea, dizziness, and may increase the risk of liver toxicity. It is best to abstain until the course is completed and you have consulted your doctor.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to ceftriaxone, tazobactum, or other beta-lactam antibiotics","History of severe allergic reaction to penicillins or cephalosporins","Concurrent use with calcium-containing intravenous solutions in neonates","Hyperbilirubinemic neonates","Not for intramuscular use; only intravenous route is approved for this formulation"]
⚠️ Warnings & Precautions
["Serious hypersensitivity reactions can occur; discontinue immediately if suspected.","Clostridioides difficile-associated diarrhea may occur; monitor for severe diarrhea.","Use with caution in patients with renal impairment; dose adjustment may be needed.","May cause false-positive results in certain urine glucose tests.","Prolonged use may lead to overgrowth of non-susceptible organisms.","Do not mix with calcium-containing solutions.","In neonates, avoid use with calcium-containing IV solutions due to risk of precipitation."]
🤱 Lactation Safety
Ceftriaxone is excreted in breast milk in low amounts and is generally considered compatible with breastfeeding. Tazobactum data is limited. Consult your doctor before use during lactation.
💊 Overdose Management
Overdose with this medicine is unlikely due to its intravenous administration by healthcare professionals. In case of accidental overdose, treatment should be symptomatic and supportive. Ceftriaxone is not removed by hemodialysis or peritoneal dialysis. Monitor vital signs and provide appropriate care.
⏰ Missed Dose
Since this medicine is administered by a healthcare professional, missed doses are unlikely. If a dose is missed, contact your healthcare provider to reschedule as soon as possible. Do not attempt to self-administer extra doses.
Additional Safety Advice
This medicine must be administered by a healthcare professional in a clinical setting. Inform your doctor about any allergies to antibiotics, especially penicillins or cephalosporins. Tell your doctor about all other medicines you are taking, including blood thinners, as interactions may occur. Do not use this medicine if you have a history of severe allergic reactions to beta-lactam antibiotics. Use with caution in patients with kidney or liver disease; dose adjustments may be needed. Avoid alcohol during treatment as it may worsen side effects. Complete the full course as prescribed, even if you feel better, to prevent resistance. Report any signs of superinfection such as oral thrush or vaginal yeast infection.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to have reduced kidney function and may require dose adjustment. Monitor renal function closely and watch for signs of toxicity.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before using this medicine. Ceftriaxone is generally considered safe, but tazobactum should be used only if clearly needed.
🏥 Post-Surgery Considerations
This medicine may be used to prevent or treat surgical site infections. Follow your surgeon's instructions for use and monitoring.
🦷 Dental Procedures
Inform your dentist if you are on this medicine. It may be used for prophylaxis in certain dental procedures for patients at risk of endocarditis, but consult your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Rest is recommended during acute infection. Gradually resume light activities as you recover. Avoid strenuous exercise until your doctor approves.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is given in a healthcare setting, so you may need to adjust your work schedule for administration. You may feel tired or dizzy; avoid driving or operating heavy machinery until you know how it affects you.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Complete the full prescribed course to prevent recurrence and resistance. If you experience severe side effects, contact your doctor immediately.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to antibiotic resistance and superinfections. Prolonged therapy requires monitoring of kidney and liver function, and blood counts. Use only for the prescribed duration.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
For less severe infections, oral antibiotics may be used after initial IV therapy.
Evidence: Well-establishedDepending on culture results, other antibiotics may be more appropriate.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are established. However, antibiotics may reduce the effectiveness of live bacterial vaccines like typhoid vaccine. Consult your doctor for timing.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate the powder unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label intact. Keep a copy of your prescription and doctor's note. Since it is an injectable, it is usually administered in a healthcare setting; plan ahead for doses during travel. Store at room temperature, away from direct sunlight. Check customs regulations for carrying injectable antibiotics across borders.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within hours, but noticeable improvement in symptoms may take 24-48 hours. Complete the full course as prescribed.
A: This medicine may cause dizziness; avoid driving or operating machinery until you know how it affects you.
A: Ceftriaxone is generally considered safe in pregnancy when needed. Tazobactum should be used only if clearly indicated. Consult your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for cefbact t 250 mg/31.25 mg injection
View AllAlternative brands with exact same active ingredient:
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Twinlet 250 mg/31.25 mg InjectionMedopharm ₹31.55 79.2% CHEAPER
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maxceft ct 250 mg/31.25 mg injectionAlembic Pharmaceuticals Ltd ₹35.16 76.8% CHEAPER
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zenoxim xp kid 250mg/31.25mg injectionIndchemie Health Specialities Pvt Ltd ₹38.91 74.3% CHEAPER
-
Symtaz P 250 mg/31.25 mg InjectionSymbiotic Drugs ₹39.66 73.8% CHEAPER
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agicef t 250mg/31.25mg injectionAegle Healthcare ₹40.00 73.6% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure viral infections.
Fact: This medicine is effective only against bacterial infections and not viruses. - Myth: It can be taken orally.
Fact: This medicine is for intravenous use only and must be given by a healthcare professional.
🔄 Alternative Options
Generic Alternatives
- Ceftriaxone + Tazobactum injection
Brand Alternatives
- Accutaz PS 250mg/31.25mg injection