cardicure lp 5mg/5mg tablet
What is cardicure lp 5mg/5mg tablet used for?
Amlopres L Tablet (Amlodipine + Lisinopril) is used to treat CARDIAC. It contains Amlodipine (5mg) + Lisinopril (5mg), which Amlodipine inhibits calcium influx across cell membranes, causing vasodilation; . Always consult your doctor before use. Take as prescribed.
- Generic Name: Amlodipine + Lisinopril
- Manufacturer: Gloucester Pharma
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ cardicure lp 5mg/5mg tablet Uses & Benefits
Hypertension, chronic stable angina, vasospastic angina
Off-label uses: Heart failure (lisinopril), Raynaud's phenomenon (amlodipine)
๐ Drug Information
| Generic Name(s) | Amlodipine + Lisinopril |
| Brand Name | Amlopres L Tablet |
| Manufacturer | Gloucester Pharma |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Calcium channel blocker + ACE inhibitor |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC, protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Amlodipine inhibits calcium influx across cell membranes, causing vasodilation; Lisinopril inhibits ACE, reducing angiotensin II and aldosterone
Mechanism Steps
๐ก How to Take cardicure lp 5mg/5mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of cardicure lp 5mg/5mg tablet
โ Common Side Effects
- Edema
- Dizziness
- Headache
- Cough
- Fatigue
๐จ Serious Side Effects
- Angioedema
- Hyperkalemia
- Acute renal failure
- Hepatotoxicity
โ ๏ธ Rare Side Effects
- Stevens-Johnson syndrome
- Agranulocytosis
- Pancreatitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Potassium-sparing diuretics | Major | Increased risk of hyperkalemia |
| Lithium | Major | Increased lithium toxicity |
| NSAIDs | Major | Reduced antihypertensive effect |
| Beta-blockers | Moderate | Increased risk of bradycardia |
| Digoxin | Moderate | Increased digoxin levels |
| CYP3A4 inhibitors | Moderate | Increased amlodipine levels |
| Antacids | Minor | Reduced absorption of lisinopril |
| Cimetidine | Minor | Possible increased amlodipine levels |
๐จ Major Interactions
- Potassium-sparing diuretics
- Lithium
- NSAIDs
โก Moderate Interactions
- Beta-blockers
- Digoxin
- CYP3A4 inhibitors
โน๏ธ Minor Interactions
- Antacids
- Cimetidine
๐ฝ๏ธ Food Interactions
Grapefruit juice may increase amlodipine levels; high-fat meal may reduce absorption
๐ท Alcohol Interaction
May potentiate hypotensive effects
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, history of angioedema, bilateral renal artery stenosis, pregnancy
๐ Monitoring Parameters
Blood pressure, heart rate, serum potassium, renal function, liver function
๐คฑ Lactation Safety
Not recommended; amlodipine and lisinopril excreted in breast milk
๐ Overdose Management
Gastric lavage, activated charcoal, supportive care; calcium gluconate for amlodipine overdose
โฐ Missed Dose
Take as soon as remembered; skip if almost time for next dose; do not double dose