Agscab Lotion (Permethrin 5% w/v): Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction: swelling of face, lips, throat, difficulty breathing.
- Severe skin reaction: blistering, peeling, or severe rash.
- Signs of infection: increased pain, swelling, redness, pus, or fever.
- No improvement after 2 weeks of treatment.
- Symptoms worsen or spread to other areas.
- Accidental ingestion of the lotion.
If experiencing severe symptoms, call emergency services immediately.
What is canomite 5% lotion used for?
This medicine is a topical lotion containing permethrin 5% w/v, used to treat scabies by killing the mites and their eggs. It is applied from the neck down, left on for 8-14 hours, and then washed off.
- Generic Name: Permethrin
- Manufacturer: Canopy Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 canomite 5% lotion के बारे में (Hindi Summary)
उपयोग: यह दवा परमेथ्रिन 5% w/v युक्त एक टॉपिकल लोशन है, जिसका उपयोग खुजली (स्केबीज) के इलाज के लिए किया जाता है। यह स्केबीज के कारण होने वाले कीड़ों को मारती है और खुजली व दाने को ठीक करती है। इसे गर्दन से नीचे पूरे शरीर पर लगाया जाता है और 8-14 घंटे तक छोड़ दिया जाता है, फिर धो लिया जाता है। यह दवा बच्चों और वयस्कों दोनों के लिए उपयुक्त है, लेकिन 2 महीने से छोटे बच्चों में इसका उपयोग नहीं करना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में लगाने की जगह पर खुजली, लालिमा, झनझनाहट या जलन शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। कभी-कभी त्वचा सूखी हो सकती है या दाने निकल सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि चेहरे, होंठ या गले में सूजन, सांस लेने में कठिनाई या गंभीर दाने हों तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल बाहरी उपयोग के लिए है। आंखों, मुंह और अन्य श्लेष्मा झिल्ली के संपर्क से बचें। टूटी या घायल त्वचा पर न लगाएं। 2 महीने से छोटे बच्चों में डॉक्टर की सलाह के बिना उपयोग न करें। निर्धारित मात्रा से अधिक या अधिक बार उपयोग न करें। लगाने के बाद हाथ धो लें। बच्चों की पहुंच से दूर रखें। गर्भवती महिलाएं उपयोग से पहले डॉक्टर से सलाह लें। स्तनपान कराने वाली महिलाएं स्तन क्षेत्र पर न लगाएं। यदि लक्षण बने रहें तो डॉक्टर से मिलें।
💊 canomite 5% lotion Uses & Benefits
- [{"condition":"Scabies","description":"This medicine is used to treat scabies, a skin infestation caused by the Sarcoptes scabiei mite.
- It kills the mites and their eggs, relieving itching and rash.","evidence":"Well-established"},{"condition":"Lice infestation (pediculosis)","description":"Permethrin 5% lotion may be used to treat lice infestations, although lower strengths are typically used for head lice.
- It kills lice and their eggs.","evidence":"Established"}]
Off-label uses: [{"condition":"Cutaneous larva migrans","description":"Sometimes prescribed off-label to treat creeping eruption caused by hookworm larvae.","evidence":"Limited"}]
Primary treatment for: Scabies
Also treats: Pediculosis
📋 Drug Information
| Generic Name(s) | Permethrin |
| Brand Name | Alscab Soap |
| Manufacturer | Canopy Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | Ectoparasiticides |
| Route of Administration | Topical |
| Storage | Store at room temperature (15-30°C). Keep away from direct sunlight and moisture. Do not freeze. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | WHO recommends permethrin 5% cream or lotion as a first-line treatment for scabies. |
| ICMR Guideline | ICMR guidelines also recommend permethrin 5% as a first-line treatment for scabies in India. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by interfering with the function of voltage-gated sodium channels in the nerve cells of mites and lice. Permethrin binds to these channels and prolongs their opening, leading to continuous sodium influx and repetitive nerve firing. This causes paralysis and eventual death of the parasite. The medicine has low toxicity to humans because human sodium channels are less sensitive to permethrin at therapeutic concentrations.
Mechanism Steps
💡 How to Take canomite 5% lotion
Strength: Lotion containing permethrin 5% w/v.
Dosage Information
| Adult Dosage | For scabies, the usual adult dose is to apply a thin layer of this medicine to all areas of the body from the neck down to the toes, including the soles of the feet, and leave it on for 8 to 14 hours, then wash off thoroughly. For lice, apply to affected area and leave on for 10 minutes, then rinse. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | For children 2 months and older, apply a thin layer to the entire body from the neck down, leave on for 8 to 14 hours, then wash off. For infants, include the scalp and forehead, avoiding the eyes and mouth. Pediatric dosing is not established from available information for children under 2 months. Consult a pediatrician. |
| Elderly Dosage | Elderly patients can use this medicine as directed for adults. However, they may be more susceptible to skin irritation. Monitor for any adverse effects. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No dosage adjustment is necessary for renal impairment due to minimal systemic absorption. |
| Hepatic Impairment | No dosage adjustment is necessary for hepatic impairment due to minimal systemic absorption. |
| Maximum Daily Dose | The maximum daily dose is not applicable as this medicine is typically used as a single application. Do not apply more than once daily unless directed by a doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of canomite 5% lotion
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to permethrin or any component of the formulation","Use on broken or inflamed skin","Use in children under 2 months of age"]
⚠️ Warnings & Precautions
["For external use only. Do not ingest.","Avoid contact with eyes, mouth, and mucous membranes.","Do not apply to the face or scalp unless directed by a doctor.","Do not use on large areas of the body without medical advice.","Keep away from children.","If accidental ingestion occurs, seek medical help immediately.","Do not use for prolonged periods without consulting a doctor.","If symptoms persist after 2 weeks, consult a doctor."]
🤱 Lactation Safety
Permethrin is excreted in breast milk in small amounts, but it is generally considered safe for nursing mothers. Apply to the affected area and avoid applying to the breast area to prevent infant exposure. Consult your doctor.
💊 Overdose Management
Overdose from topical application is unlikely due to low absorption. If accidental ingestion occurs, seek immediate medical attention. Symptoms of overdose may include dizziness, headache, nausea, vomiting, and in severe cases, seizures. Treatment is supportive and symptomatic.
⏰ Missed Dose
This medicine is usually applied as a single dose. If you miss a dose, apply it as soon as you remember, unless it is almost time for the next dose. Do not apply a double dose to make up for a missed one. Consult your doctor if unsure.
Additional Safety Advice
For external use only. Avoid contact with eyes, mouth, and other mucous membranes. If accidental contact occurs, rinse thoroughly with water. Do not apply to broken or irritated skin. Do not use on children under 2 months of age unless directed by a doctor. Do not use more than the prescribed amount or more often than directed. Wash hands thoroughly after applying. Avoid inhaling the lotion. Keep out of reach of children. Do not use if you are allergic to permethrin or any ingredient. Pregnant women should consult a doctor before use. Nursing mothers should avoid applying to the breast area. If symptoms persist after treatment, consult a doctor. Do not share this medicine with others. Do not use for any other condition without medical advice.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have thinner skin and are more prone to skin irritation. Use with caution and monitor for adverse effects. No dosage adjustment is needed.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. Permethrin is generally considered safe during pregnancy, but individual circumstances may vary.
🏥 Post-Surgery Considerations
If you have recently had surgery, consult your doctor before applying this medicine to surgical wounds or nearby areas. Avoid applying to broken skin or incisions.
🦷 Dental Procedures
This medicine is for topical use and does not affect dental procedures. However, inform your dentist about all medicines you are using.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
There are no specific exercise restrictions while using this medicine. However, avoid strenuous activities that cause excessive sweating immediately after application, as it may reduce the effectiveness or cause irritation. Wait until the lotion is washed off before resuming normal activities.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is applied topically and left on for 8-14 hours, usually overnight. It may cause mild skin irritation but generally does not affect your ability to work or drive. However, if you experience dizziness or drowsiness (rare), avoid driving or operating machinery until you feel alert.
🛑 When to Stop This Medicine
Stop using this medicine and consult a doctor if you experience severe allergic reactions, severe skin irritation, or if your symptoms do not improve after 2 weeks. Do not stop treatment prematurely unless advised by your doctor.
📅 Long-Term Use Effects
Long-term effects of topical permethrin are not well established because it is typically used as a single application. Repeated use may increase the risk of skin irritation or allergic contact dermatitis. There is no evidence of systemic toxicity from topical use. If repeated treatments are needed, consult a doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
An alternative topical acaricide for scabies, especially for those allergic to permethrin.
Evidence: EstablishedUsed for crusted scabies or when topical treatment fails.
Evidence: Well-establishedAn older alternative, safe for infants and pregnant women.
Evidence: Established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. You can receive vaccinations while using this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging with the prescription label intact. Bring a copy of your prescription in case customs or security ask for it. Store it at room temperature, away from direct sunlight and moisture. If you are traveling across time zones, this medicine is usually applied as a single dose, so time zone adjustments are not typically needed. However, if you are on a multiple-dose regimen, consult your doctor for guidance. Keep it in your carry-on luggage if possible, and ensure it is not exposed to extreme temperatures.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts killing mites soon after application, but itching and rash may take 2-4 weeks to fully resolve as the skin heals.
A: It is generally not recommended to apply on the face unless directed by a doctor. Avoid contact with eyes, mouth, and mucous membranes.
A: Yes, it is safe for children over 2 months of age when used as directed. Consult a pediatrician for children under 2 months.
A: Permethrin is considered safe during pregnancy when used as directed. However, consult your doctor before use.
A: This medicine is usually a single application. If you miss a dose, apply it as soon as you remember unless it is almost time for the next dose. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for canomite 5% lotion
View AllAlternative brands with exact same active ingredient:
-
scabicip lotionCipla Ltd ₹18.75 71.6% CHEAPER
-
scabiplus lotionParker Robinson Pvt Ltd ₹37.72 42.8% CHEAPER
-
biomethrin lotionZydus Wellness Product Ltd ₹39.40 40.3% CHEAPER
-
nedax lotionGlaxo SmithKline Pharmaceuticals Ltd ₹44.94 31.9% CHEAPER
-
perscab plus lotionElder Pharmaceuticals Ltd ₹46.17 30% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Scabies is caused by poor hygiene.
Fact: Scabies can affect anyone, regardless of hygiene. It is caused by a mite that burrows into the skin. - Myth: You only need to treat the person with symptoms.
Fact: All household members and close contacts should be treated simultaneously to prevent reinfestation. - Myth: Permethrin lotion works immediately.
Fact: Itching may persist for up to 2-4 weeks after treatment as the skin heals, even though the mites are killed.
🔄 Alternative Options
Generic Alternatives
- Permethrin 5% lotion (generic)
Brand Alternatives
- Permethrin 5% lotion (various brands)