candipoz-gr tablet - Uses, Price, Side Effects & Substitutes
What is candipoz-gr tablet used for?
Candipoz-GR Tablet (Posaconazole) is used to treat ANTI INFECTIVES. It contains Posaconazole (100mg), which Inhibits fungal cytochrome P450 14ฮฑ-demethylase (CYP51), blocking ergosterol sy. Always consult your doctor before use. Take as prescribed.
- Generic Name: Posaconazole
- Manufacturer: Glenmark Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ candipoz-gr tablet Uses & Benefits
Prophylaxis of invasive fungal infections in immunocompromised patients; treatment of oropharyngeal candidiasis; treatment of aspergillosis, fusariosis, chromoblastomycosis, and coccidioidomycosis.
Off-label uses: Treatment of invasive candidiasis, Treatment of histoplasmosis, Treatment of blastomycosis
๐ Drug Information
| Generic Name(s) | Posaconazole |
| Brand Name | Candipoz-GR Tablet |
| Manufacturer | Glenmark Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Fungal ergosterol synthesis inhibitor |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits fungal cytochrome P450 14ฮฑ-demethylase (CYP51), blocking ergosterol synthesis.
Mechanism Steps
๐ก How to Take candipoz-gr tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of candipoz-gr tablet
โ Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Headache
- Dizziness
- Fatigue
- Fever
- Rash
๐จ Serious Side Effects
- Hepatotoxicity
- QT prolongation
- Torsades de pointes
- Adrenal insufficiency
- Hypokalemia
- Hypomagnesemia
โ ๏ธ Rare Side Effects
- Hemolytic uremic syndrome
- Thrombotic thrombocytopenic purpura
- Peripheral neuropathy
- Pancreatitis
- Stevens-Johnson syndrome
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Sirolimus | Major | Increased sirolimus levels, risk of toxicity |
| Pimozide | Major | Increased risk of QT prolongation |
| Quinidine | Major | Increased risk of QT prolongation |
| Lovastatin | Major | Increased risk of rhabdomyolysis |
| Simvastatin | Major | Increased risk of rhabdomyolysis |
| Ergot alkaloids | Major | Ergotism risk |
| Cisapride | Major | Increased risk of QT prolongation |
| Terfenadine | Major | Increased risk of QT prolongation |
| Astemizole | Major | Increased risk of QT prolongation |
| Cyclosporine | Moderate | Increased cyclosporine levels |
| Tacrolimus | Moderate | Increased tacrolimus levels |
| Midazolam | Moderate | Increased midazolam levels |
| Alprazolam | Moderate | Increased alprazolam levels |
| Calcium channel blockers | Moderate | Increased CCB levels |
| HMG-CoA reductase inhibitors | Moderate | Increased statin levels |
| Phenytoin | Moderate | Decreased posaconazole levels |
| Carbamazepine | Moderate | Decreased posaconazole levels |
| Rifabutin | Moderate | Decreased posaconazole levels |
| Cimetidine | Moderate | Decreased posaconazole levels |
| Oral contraceptives | Minor | Possible decreased contraceptive efficacy |
| Digoxin | Minor | Possible increased digoxin levels |
| Sulfonylureas | Minor | Possible hypoglycemia |
๐จ Major Interactions
- Sirolimus
- Pimozide
- Quinidine
- Lovastatin
- Simvastatin
- Ergot alkaloids
- Cisapride
- Terfenadine
- Astemizole
โก Moderate Interactions
- Cyclosporine
- Tacrolimus
- Midazolam
- Alprazolam
- Calcium channel blockers
- HMG-CoA reductase inhibitors
- Phenytoin
- Carbamazepine
- Rifabutin
- Cimetidine
โน๏ธ Minor Interactions
- Oral contraceptives
- Digoxin
- Sulfonylureas
๐ฝ๏ธ Food Interactions
High-fat meal increases absorption; avoid grapefruit juice.
๐ท Alcohol Interaction
Avoid alcohol; may increase hepatotoxicity risk.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to posaconazole or excipients; coadministration with CYP3A4 substrates that prolong QT interval.
๐ Monitoring Parameters
Liver function tests (ALT, AST, bilirubin); ECG for QT interval; renal function; posaconazole trough levels (if available).
๐คฑ Lactation Safety
Not recommended; excreted in animal milk.
๐ Overdose Management
Supportive care; no specific antidote; hemodialysis not effective.
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for candipoz-gr tablet
View AllAlternative brands with exact same active ingredient (Posaconazole (100mg)):
-
posatral tabletMylan Pharmaceuticals Pvt Ltd โน3,712.00 22.8% CHEAPER
-
posahit 100mg tabletSun Pharmaceutical Industries Ltd โน4,185.27 13% CHEAPER
-
posaforce 100mg tabletMankind Pharma Ltd โน5,624.99 16.9% COSTLIER
-
picasa-gr tabletIntas Pharmaceuticals Ltd โน5,661.56 17.7% COSTLIER
-
posoxil gr 100mg tabletHetero Healthcare Limited โน7,000.00 45.5% COSTLIER
-
poscosafe tabletSafecon Lifesciences โน8,625.00 79.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.