Camphor (0.01% w/v) + Carboxymethylcellulose (0.5% w/v) + Menthol (0.005% w/v) + Naphazoline (0.05% w/v) + Phenylephrine (0.012% w/v) + Stabilized Oxychloro (0.005% w/v) (Medical Monograph)

Overview

A multi-component ophthalmic solution combining decongestants, lubricants, and mild antiseptic agents for symptomatic relief of ocular redness, irritation, and minor infections. It is primarily indicated for allergic conjunctivitis, minor eye irritations, and as a lubricant for dry eyes with associated redness. The combination provides rapid vasoconstriction (Naphazoline, Phenylephrine), soothing and cooling relief (Menthol, Camphor), mucoadhesive lubrication (Carboxymethylcellulose), and antimicrobial action (Stabilized Oxychloro complex).

The combination works through multiple synergistic mechanisms: 1) Naphazoline and Phenylephrine are alpha-1 and alpha-2 adrenergic agonists causing vasoconstriction of conjunctival blood vessels, reducing redness and edema. 2) Carboxymethylcellulose acts as a demulcent and lubricant, stabilizing the tear film and protecting the ocular surface. 3) Menthol and Camphor stimulate TRPM8 cold receptors, providing a cooling, soothing sensation and mild local anesthetic effect. 4) Stabilized Oxychloro complex (Purite) releases hypochlorous acid, a natural oxidant with antimicrobial activity against pathogens, and acts as a preservative.