c-roxim 750mg injection

4.4 (18 reviews)

Cefuroxime (750mg)

🏭 Troikaa Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is c-roxim 750mg injection used for?

Altacef 500 Tablet (Cefuroxime) is used to treat ANTI INFECTIVES. It contains Cefuroxime (750mg), which Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. Always consult your doctor before use. Take as prescribed.

Generic Name: Cefuroxime
Manufacturer: Troikaa Pharmaceuticals Ltd
Form: Allopathy
Pregnancy Category: B
Prescription Required: Yes

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 c-roxim 750mg injection Uses & Benefits

Upper and lower respiratory tract infections, urinary tract infections, skin and soft tissue infections, otitis media, sinusitis, gonorrhea, Lyme disease.

Off-label uses: Prophylaxis for surgical infections, treatment of bone and joint infections.

📋 Drug Information

Generic Name(s)	Cefuroxime
Brand Name	Altacef 500 Tablet
Manufacturer	Troikaa Pharmaceuticals Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	ANTI INFECTIVES
Action Class	Cephalosporins: 2nd generation
Route of Administration	Oral
Storage	Store at room temperature (20-25°C); protect from light and moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed after oral administration; food increases absorption.

DistributionDistributes widely into body tissues and fluids, including pleural fluid, synovial fluid, bone, and CSF (when meninges inflamed).

Protein Binding33-50%

MetabolismNot significantly metabolized; primarily renal excretion.

Half-Life1-2 hours

ExcretionRenal (80-90% unchanged in urine within 24 hours)

BioavailabilityApproximately 37% (oral); increased with food.

Onset of ActionRapid; within 1 hour for most infections.

Peak Plasma Time2-3 hours (oral)

Duration of ActionApproximately 8-12 hours

How It Works

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), inhibiting transpeptidase and autolysin activity.

Mechanism Steps

1Cefuroxime binds to penicillin-binding proteins (PBPs) on bacterial cell wall.

2Inhibits transpeptidase enzyme, preventing cross-linking of peptidoglycan chains.

3Activates autolytic enzymes (autolysins) leading to cell wall lysis.

💡 How to Take c-roxim 750mg injection

Follow your doctor's prescription exactly.

⚠️ Side Effects of c-roxim 750mg injection

✅ Common Side Effects

Diarrhea
Nausea
Vomiting
Rash
Injection site reactions (if IV)

🚨 Serious Side Effects

Severe allergic reactions (anaphylaxis)
Clostridioides difficile diarrhea
Seizures (high doses)
Stevens-Johnson syndrome

⚠️ Rare Side Effects

Hemolytic anemia
Interstitial nephritis
Hepatitis
Agranulocytosis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Warfarin	Major	Increased bleeding risk
Probenecid	Major	Decreased renal excretion of cefuroxime, increased levels
Live typhoid vaccine	Major	Reduced vaccine efficacy
BCG vaccine	Major	Reduced vaccine efficacy
Loop diuretics	Moderate	Increased nephrotoxicity risk
Aminoglycosides	Moderate	Increased nephrotoxicity risk
Oral contraceptives	Moderate	Reduced contraceptive efficacy
Antacids	Minor	Decreased absorption of cefuroxime
H2 antagonists	Minor	Decreased absorption of cefuroxime
Proton pump inhibitors	Minor	Decreased absorption of cefuroxime

🚨 Major Interactions

Warfarin
Probenecid
Live typhoid vaccine
BCG vaccine

⚡ Moderate Interactions

Loop diuretics
Aminoglycosides
Oral contraceptives
BCG (intravesical)

ℹ️ Minor Interactions

Antacids
H2 antagonists
Proton pump inhibitors

🍽️ Food Interactions

Food increases absorption; take with food.

🍷 Alcohol Interaction

No known interaction; but may increase risk of disulfiram-like reaction (rare).

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to cefuroxime or other cephalosporins; previous immediate hypersensitivity reaction to penicillins.

📊 Monitoring Parameters

Renal function, signs of hypersensitivity, superinfection, bleeding (if on warfarin).

🤱 Lactation Safety

Excreted in breast milk in small amounts; generally considered compatible with breastfeeding.

💊 Overdose Management

Supportive care; hemodialysis may enhance elimination.

⏰ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose and resume regular schedule. Do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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🔄 Substitutes for c-roxim 750mg injection

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Alternative brands with exact same active ingredient (Cefuroxime (750mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Regular Customer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Trusted Reviewer Jul 10, 2026

Found this to be a helpful product. Good results.

Certified Buyer Jul 10, 2026