C Pin Eye Drop (Timolol 0.25%): Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing, wheezing, or chest tightness
- Unusually slow or irregular heartbeat
- Severe dizziness or fainting
- Sudden vision loss or severe eye pain
- Swelling of face, lips, or throat
- Signs of eye infection such as discharge, redness, or pain
- Persistent confusion or depression
If experiencing severe symptoms, call emergency services immediately.
What is c pin eye drop used for?
This medicine is an eye drop containing timolol 0.25% w/v, a beta-blocker used to lower high pressure inside the eye in conditions like open-angle glaucoma and ocular hypertension. It works by reducing the production of fluid in the eye. It is usually applied twice daily as prescribed by an eye doctor.
- Generic Name: Timolol
- Manufacturer: Calibre Pharmaceutical
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 c pin eye drop के बारे में (Hindi Summary)
उपयोग: यह दवा आंखों की बूंदों के रूप में उपयोग की जाती है और इसमें टिमोलोल 0.25% w/v होता है। यह आंखों के अंदर के दबाव को कम करने में मदद करती है, जो ग्लूकोमा और ऑक्यूलर हाइपरटेंशन जैसी स्थितियों में बढ़ जाता है। यह बीटा-ब्लॉकर वर्ग की दवा है जो आंखों में तरल पदार्थ के उत्पादन को कम करके काम करती है। इसे आमतौर पर दिन में दो बार आंखों में डाला जाता है, लेकिन इसका उपयोग डॉक्टर के निर्देशानुसार ही करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में आंखों में जलन, धुंधली दृष्टि, आंखों का लाल होना, सिरदर्द और थकान शामिल हैं। कभी-कभी यह दिल की धड़कन धीमी कर सकती है, रक्तचाप कम कर सकती है, और सांस लेने में कठिनाई पैदा कर सकती है, खासकर अस्थमा या हृदय रोग वाले लोगों में। यदि आपको सांस लेने में तकलीफ, चक्कर आना, या धड़कन असामान्य लगे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा का उपयोग करने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं, विशेषकर अस्थमा, हृदय रोग, या मधुमेह के बारे में बताएं। आंखों में डालने के बाद आंख के भीतरी कोने को 1-2 मिनट तक दबाएं ताकि दवा खून में कम जाए। कॉन्टैक्ट लेंस पहनने से पहले उन्हें निकाल लें और दवा डालने के 15 मिनट बाद ही वापस पहनें। ड्रॉपर की नोक को आंख या किसी सतह से न छुएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। इस दवा को अचानक बंद न करें, क्योंकि इससे आंखों का दबाव बढ़ सकता है।
💊 c pin eye drop Uses & Benefits
[{"condition":"Open-angle glaucoma","description":"This medicine is used to lower intraocular pressure in patients with primary open-angle glaucoma, helping to prevent optic nerve damage and vision loss.","evidence":"Well-established"},{"condition":"Ocular hypertension","description":"It is prescribed to reduce elevated intraocular pressure in individuals who have ocular hypertension but no signs of glaucomatous damage yet.","evidence":"Well-established"},{"condition":"Secondary glaucoma","description":"Sometimes used to manage elevated eye pressure associated with other conditions such as pseudoexfoliation or pigment dispersion syndrome.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Infantile hemangioma","description":"Topical timolol has been studied off-label for superficial infantile hemangiomas, but this eye drop formulation is not intended for that use.","evidence":"Limited"},{"condition":"Prevention of migraine","description":"Oral timolol is sometimes used for migraine prophylaxis, but the eye drop form is not indicated for this purpose.","evidence":"Limited"}]
Primary treatment for: Open-angle glaucoma
Also treats: Ocular hypertension, Secondary glaucoma
📋 Drug Information
| Generic Name(s) | Timolol |
| Brand Name | Aurotim Eye Drop |
| Manufacturer | Calibre Pharmaceutical |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OPHTHAL |
| Action Class | Beta blocker (Topical) |
| Route of Administration | Ophthalmic (topical ocular) |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and excessive heat. Keep the bottle tightly closed when not in use. Do not freeze. |
| Shelf Life | Typically 24 months from the date of manufacture, but refer to the expiry date printed on the packaging. Discard the solution 4 weeks after opening the bottle, as recommended for most eye drops. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Timolol is a non-selective beta-adrenergic receptor antagonist. When instilled into the eye, it blocks beta-1 and beta-2 receptors in the ciliary epithelium, which reduces the production of aqueous humor by the ciliary body. This decrease in aqueous humor formation leads to a reduction in intraocular pressure. Timolol does not affect the outflow of aqueous humor but primarily acts on its inflow. Because it is a non-selective beta-blocker, it can also affect beta receptors elsewhere in the body if absorbed systemically, potentially causing effects on the heart and lungs.
Mechanism Steps
💡 How to Take c pin eye drop
Strength: Ophthalmic solution, 0.25% w/v (2.5 mg/mL)
Dosage Information
| Adult Dosage | The usual adult dose is one drop of 0.25% solution instilled into the affected eye(s) twice daily. Some patients may require a higher concentration (0.5%) or once-daily dosing with a gel-forming solution, as determined by the ophthalmologist. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and response to therapy. Do not change the dose without consulting your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatric ophthalmologist. |
| Elderly Dosage | Elderly patients may be more sensitive to the systemic effects of timolol, such as bradycardia and hypotension. Use with caution and monitor vital signs. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No specific dosage adjustment is provided in the available information for renal impairment. However, since timolol is excreted by the kidneys, caution is advised in patients with severe renal impairment. Consult your doctor. |
| Hepatic Impairment | No specific dosage adjustment is provided in the available information for hepatic impairment. Timolol is metabolized in the liver, so caution is advised in patients with severe hepatic impairment. Consult your doctor. |
| Maximum Daily Dose | The maximum recommended dose for ophthalmic use is one drop of 0.5% solution twice daily, but the exact maximum should be determined by your ophthalmologist. Do not exceed the prescribed dose. |
Dosage Timeline
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of c pin eye drop
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Propranolol | Major | |
| Verapamil | Major | |
| Digoxin | Major | |
| Quinidine | Moderate | |
| Fluoxetine | Moderate | |
| Clonidine | Moderate | |
| Insulin | Moderate | |
| Ibuprofen | Minor | |
| Reserpine | Minor | |
| Alcohol | Minor |
🚨 Major Interactions
- Oral beta-blockers (e.g., propranolol, metoprolol)
- Calcium channel blockers (e.g., verapamil, diltiazem)
- Digitalis glycosides (e.g., digoxin)
⚡ Moderate Interactions
- CYP2D6 inhibitors (e.g., quinidine, fluoxetine, paroxetine)
- Clonidine
- Insulin and oral antidiabetics
🍷 Alcohol Interaction
Alcohol may enhance the blood pressure-lowering effect of timolol and increase the risk of dizziness or fainting. It is advisable to limit or avoid alcohol while using this medicine, especially when starting treatment.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Asthma or a history of obstructive airway disease","Severe chronic obstructive pulmonary disease (COPD)","Sinus bradycardia, sick sinus syndrome, or second- or third-degree atrioventricular block","Cardiogenic shock or uncontrolled heart failure","Hypersensitivity to timolol or any component of the formulation"]
⚠️ Warnings & Precautions
["This medicine may cause systemic beta-blockade; use with caution in patients with heart or lung disease.","Do not use if you have an eye infection or injury unless advised by your doctor.","Remove contact lenses before use and wait 15 minutes before reinserting.","Avoid touching the dropper tip to any surface to prevent contamination.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Do not stop using this medicine abruptly without consulting your doctor.","Use with caution in patients with diabetes, as it may mask hypoglycemia symptoms.","May cause drowsiness or blurred vision; avoid driving or operating machinery until you know how it affects you."]
🤱 Lactation Safety
Timolol is excreted in breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Consult your doctor.
💊 Overdose Management
Overdose from ocular timolol is unlikely due to the small amount in each drop. However, if accidental ingestion occurs, seek emergency medical attention. Symptoms of systemic beta-blocker overdose include severe bradycardia, hypotension, bronchospasm, and heart failure. Treatment is supportive and may include atropine, sympathomimetics, or cardiac pacing as needed.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Before using this medicine, inform your doctor if you have a history of asthma, chronic obstructive pulmonary disease, heart block, heart failure, low blood pressure, or diabetes, as timolol can affect these conditions. Do not use this medicine if you have an active eye infection or injury unless your doctor approves. To reduce systemic absorption, gently press the inner corner of your eye near the nose for one to two minutes after instilling the drop. This technique, called punctal occlusion, helps keep the medicine in the eye and minimizes its entry into the bloodstream. Remove soft contact lenses before applying the drops and wait at least 15 minutes before reinserting them, as the preservative in the solution may be absorbed by the lenses. Do not touch the dropper tip to any surface, including your eye, to avoid contamination. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Do not stop using this medicine abruptly without consulting your eye doctor, as sudden discontinuation can lead to a dangerous rise in eye pressure.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the systemic effects of timolol, such as bradycardia, hypotension, and confusion. Use with caution and monitor vital signs regularly. Dose adjustments may be necessary based on renal and hepatic function.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your ophthalmologist and obstetrician before conception. Timolol may not be the preferred treatment during pregnancy. Alternative eye drops with a better safety profile may be considered.
🏥 Post-Surgery Considerations
After eye surgery, your doctor will advise whether to continue this medicine. In some cases, it may be temporarily stopped or replaced with another medication. Follow your surgeon's instructions carefully.
🦷 Dental Procedures
Inform your dentist that you are using this medicine, as it may interact with certain medications used during dental procedures, such as epinephrine. Your dentist may need to adjust the anesthetic or monitor your heart rate.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe while using this medicine. However, if you have heart or lung conditions, consult your doctor before starting any new exercise regimen. Avoid activities that involve rapid head movements or inverted positions, as they may temporarily increase eye pressure.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause temporary blurred vision or dizziness after application. Avoid driving or operating heavy machinery until your vision is clear. If you experience systemic side effects like fatigue or slow heartbeat, inform your employer if your job involves safety-sensitive tasks. Most people can continue their normal work routine with proper precautions.
🛑 When to Stop This Medicine
Do not stop using this medicine without consulting your ophthalmologist. If you experience serious side effects such as severe breathing difficulty, slow heartbeat, or allergic reactions, seek immediate medical attention and follow your doctor's advice on whether to continue. Your doctor may switch you to a different medication if needed.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe when monitored by an ophthalmologist. Regular check-ups are necessary to monitor intraocular pressure, visual fields, and optic nerve health. Prolonged use may lead to tolerance, requiring additional or alternative treatments. Systemic effects such as bradycardia and bronchospasm may persist with long-term use, especially in susceptible individuals. Do not stop the medicine without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A laser procedure that can improve drainage of aqueous humor and lower eye pressure.
Evidence: Well-establishedA surgical option for glaucoma when medications are insufficient.
Evidence: Well-establishedProstaglandin analogs, carbonic anhydrase inhibitors, or alpha-2 agonists may be used alone or in combination.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, always inform your healthcare provider about all medications you are taking before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Discard 4 weeks after opening
❌ DON'T
Do not use if solution is discolored or has particles
✈️ Traveling with This Medicine
When traveling, carry your eye drops in your hand luggage along with a copy of your prescription. Keep the bottle in its original packaging to avoid confusion at customs. Store at room temperature and protect from extreme heat or cold. If crossing time zones, continue your regular dosing schedule but consult your doctor for specific advice. Always carry enough supply for your trip and a spare bottle in case of delays.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering intraocular pressure within 30 minutes, with maximum effect in 1-2 hours. However, it may take a few weeks to achieve stable control.
A: No, you should not stop without consulting your doctor. Glaucoma is a chronic condition, and stopping treatment can lead to a dangerous rise in eye pressure and vision loss.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: Remove contact lenses before applying the drops and wait at least 15 minutes before reinserting them, as the preservative may be absorbed by the lenses.
A: Consult your doctor. Timolol is not recommended during pregnancy unless clearly necessary. Your doctor will weigh the benefits and risks.
🤔 Common Patient Concerns
🔄 Substitutes for c pin eye drop
View AllAlternative brands with exact same active ingredient:
-
lopres 0.25% eye dropMicro Labs Ltd ₹14.58 11% COSTLIER
-
Teoptic 0.25% Eye DropElder Pharmaceuticals Ltd ₹14.63 11.4% COSTLIER
-
ocutim 0.25% eye dropCipla Ltd ₹15.38 17.1% COSTLIER
-
ocobar 0.25% eye dropPCI Pharmaceuticals ₹22.90 74.4% COSTLIER
-
domolol 0.25% eye dropDoeshealth Systems Private Limited ₹48.00 265.6% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure glaucoma permanently.
Fact: This medicine helps control eye pressure but does not cure glaucoma. It must be used regularly to prevent vision loss. - Myth: If I feel fine, I can stop using the drops.
Fact: Glaucoma often has no symptoms until vision loss occurs. Stopping the drops can lead to irreversible vision damage. - Myth: This medicine only affects the eyes.
Fact: Timolol can be absorbed into the bloodstream and cause systemic effects like slow heart rate or breathing problems. - Myth: Using more drops than prescribed will work better.
Fact: Using more than prescribed does not improve effectiveness and may increase side effects. Follow your doctor's instructions exactly.
🔄 Alternative Options
Generic Alternatives
- Timolol ophthalmic solution 0.25%
Brand Alternatives
- C Pin Eye Drop