c pin eye drop - Timolol (0.25% w/v) medicine

c pin eye drop

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๐Ÿญ Calibre Pharmaceutical ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jul 5, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jul 05, 2026

What is c pin eye drop used for?

Aurotim Eye Drop (Timolol) is used to treat OPHTHAL. It contains Timolol (0.25% w/v), which Blocks beta-adrenergic receptors in the ciliary epithelium, reducing aqueous hum. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Timolol
  • Manufacturer: Calibre Pharmaceutical
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š c pin eye drop Uses & Benefits

Reduction of intraocular pressure in open-angle glaucoma and ocular hypertension.

Off-label uses: Prophylaxis of migraine (oral form); not typically for ophthalmic.

๐Ÿ“‹ Drug Information

Generic Name(s)Timolol
Brand NameAurotim Eye Drop
ManufacturerCalibre Pharmaceutical
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL
Action ClassBeta blocker (Topical)
Route of AdministrationOphthalmic (topical to the eye).
StorageStore at 15-30ยฐC (59-86ยฐF); protect from light; keep tightly closed.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMinimal systemic absorption after ocular administration; peak concentration in aqueous humor occurs within 1-2 hours.
DistributionDistributes into aqueous humor; systemic distribution is limited due to low absorption.
Protein BindingApproximately 60% bound to plasma proteins.
MetabolismPartially metabolized in the liver via CYP2D6; major metabolite is inactive.
Half-Life4-6 hours (systemic); ocular half-life is longer.
ExcretionRenal excretion of metabolites and unchanged drug (approximately 20% unchanged).
BioavailabilityLow systemic bioavailability due to extensive first-pass metabolism after ocular administration.
Onset of ActionReduction of intraocular pressure begins within 30 minutes.
Peak Plasma Time1-2 hours after ocular administration.
Duration of ActionReduction of intraocular pressure lasts up to 24 hours.

How It Works

Blocks beta-adrenergic receptors in the ciliary epithelium, reducing aqueous humor production.

Mechanism Steps

1Timolol binds to beta-1 and beta-2 adrenergic receptors on the ciliary epithelium.
2Blockade of beta-receptors inhibits adenylate cyclase, reducing cyclic AMP production.
3Decreased cyclic AMP leads to reduced aqueous humor secretion by the ciliary body.

๐Ÿ’ก How to Take c pin eye drop

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of c pin eye drop

โœ… Common Side Effects

  • Burning or stinging on instillation
  • Blurred vision
  • Eye irritation
  • Conjunctival hyperemia

๐Ÿšจ Serious Side Effects

  • Bradycardia
  • Heart block
  • Bronchospasm
  • Hypotension
  • Syncope

โš ๏ธ Rare Side Effects

  • Depression
  • Confusion
  • Hallucinations
  • Masked hypoglycemia
  • Sexual dysfunction

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Calcium channel blockers Major Increased risk of bradycardia and hypotension
Digitalis glycosides Major Increased risk of bradycardia
Epinephrine Major Hypertensive crisis and bradycardia
Clonidine Moderate Rebound hypertension upon withdrawal
Insulin Moderate Masking of hypoglycemic symptoms
Oral hypoglycemics Moderate Masking of hypoglycemic symptoms
Corticosteroids Minor Reduced antihypertensive effect
NSAIDs Minor Reduced antihypertensive effect

๐Ÿšจ Major Interactions

  • Calcium channel blockers
  • Digitalis glycosides
  • Epinephrine

โšก Moderate Interactions

  • Clonidine
  • Insulin
  • Oral hypoglycemics

โ„น๏ธ Minor Interactions

  • Corticosteroids
  • NSAIDs

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

May enhance hypotensive effects; caution advised.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Bronchial asthma, COPD, sinus bradycardia, second- or third-degree AV block, cardiogenic shock, hypersensitivity to timolol.

๐Ÿ“Š Monitoring Parameters

Intraocular pressure, heart rate, blood pressure, signs of bronchospasm.

๐Ÿคฑ Lactation Safety

Caution; excreted in breast milk in small amounts.

๐Ÿ’Š Overdose Management

Symptoms: bradycardia, hypotension, bronchospasm. Treatment: gastric lavage if ingested; supportive measures; atropine for bradycardia; beta-agonists for bronchospasm.

โฐ Missed Dose

Apply as soon as remembered; if near next dose, skip missed dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Jul 05, 2026

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๐Ÿ”„ Substitutes for c pin eye drop

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Alternative brands with exact same active ingredient (Timolol (0.25% w/v)):

Medical Note: Always consult your doctor before switching medications.

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