c gen fc cream - Ciprofloxacin (0.5% w/w) + Fluocinolone acetonide (0.025% w/w) medicine

c gen fc cream

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🏭 Dr Alexander Lab Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

What is c gen fc cream used for?

This medicine contains Ciprofloxacin (0.5% w/w) + Fluocinolone acetonide (0.025% w/w) and is used to treat DERMA. Ciprofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication. Fluoci. Always consult your doctor before use.

  • Generic Name: Ciprofloxacin + Fluocinolone acetonide
  • Manufacturer: Dr Alexander Lab Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Category C
  • Prescription Required: Yes
💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 c gen fc cream Uses & Benefits

Treatment of inflammatory skin conditions with secondary bacterial infection.

Off-label uses: Atopic dermatitis with infection, Seborrheic dermatitis with infection

📋 Drug Information

Generic Name(s)Ciprofloxacin + Fluocinolone acetonide
Brand NameCeflox-CF Cream
ManufacturerDr Alexander Lab Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassFluoroquinolone antibiotic + Corticosteroid
Route of AdministrationTopical
StorageStore at room temperature (20-25°C), away from moisture and heat.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionTopical absorption is minimal; systemic absorption may occur through inflamed skin.
DistributionDistributes into skin layers; systemic distribution if absorbed.
Protein BindingCiprofloxacin: 20-40%; Fluocinolone acetonide: ~90%
MetabolismCiprofloxacin: Hepatic (partially); Fluocinolone acetonide: Hepatic
Half-LifeCiprofloxacin: 4 hours; Fluocinolone acetonide: Not well defined topically
ExcretionCiprofloxacin: Renal (50-70% unchanged); Fluocinolone acetonide: Renal and biliary
BioavailabilityLow systemic bioavailability via topical route
Onset of ActionWithin a few days of application
Peak Plasma TimeNot applicable for topical use
Duration of ActionVaries; typically applied twice daily

How It Works

Ciprofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication. Fluocinolone acetonide binds to glucocorticoid receptors, suppressing inflammation.

Mechanism Steps

1Ciprofloxacin enters bacterial cells.
2Binds to DNA gyrase and topoisomerase IV.
3Inhibits DNA replication and transcription.
4Leads to bacterial cell death.
5Fluocinolone acetonide diffuses into cells.
6Binds to glucocorticoid receptor.
7Complex translocates to nucleus.
8Modulates gene transcription, reducing pro-inflammatory cytokines.
9Suppresses inflammation and immune response.

💡 How to Take c gen fc cream

Follow your doctor's prescription exactly.

⚠️ Side Effects of c gen fc cream

✅ Common Side Effects

Skin irritation
Burning
Itching
Dryness

🚨 Serious Side Effects

Allergic reaction
Skin atrophy
Secondary infection
Adrenal suppression (prolonged use)

⚠️ Rare Side Effects

Contact dermatitis
Hypertrichosis
Hypopigmentation

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major Increased INR and bleeding risk
Theophylline Major Increased theophylline levels, risk of toxicity
Tizanidine Major Increased tizanidine levels, hypotension, sedation
NSAIDs Moderate Increased CNS stimulation risk
Oral antidiabetics Moderate Hypoglycemia or hyperglycemia
Cyclosporine Moderate Increased nephrotoxicity risk
Caffeine Minor Decreased caffeine clearance
Dairy products Minor Reduced ciprofloxacin absorption (oral, not topical)
Antacids Minor Reduced ciprofloxacin absorption (oral, not topical)

🚨 Major Interactions

  • Warfarin
  • Theophylline
  • Tizanidine

⚡ Moderate Interactions

  • NSAIDs
  • Oral antidiabetics
  • Cyclosporine

🍷 Alcohol Interaction

No known interaction with topical use.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to any component, viral skin infections, fungal infections, tuberculosis of skin.

🤱 Lactation Safety

Use with caution; avoid application to breast area.

💊 Overdose Management

Topical overdose unlikely; if excessive application, wash off and treat symptomatically.

⏰ Missed Dose

Apply as soon as remembered; skip if almost time for next dose.

🔄 Substitutes for c gen fc cream

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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