c biotic ear drop - Uses, Price, Side Effects & Substitutes
What is c biotic ear drop used for?
Audotic Ear Drop (Lidocaine + Clotrimazole) is used to treat OTOLOGICALS. It contains Lidocaine (2% w/v) + Clotrimazole (1% w/v), which Lidocaine blocks sodium channels, inhibiting nerve impulse conduction. Clotrimaz. Always consult your doctor before use. Take as prescribed.
- Generic Name: Lidocaine + Clotrimazole
- Manufacturer: Elixir Life Care Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ c biotic ear drop Uses & Benefits
Otitis externa, fungal ear infections.
Off-label uses: None established.
๐ Drug Information
| Generic Name(s) | Lidocaine + Clotrimazole |
| Brand Name | Audotic Ear Drop |
| Manufacturer | Elixir Life Care Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OTOLOGICALS |
| Action Class | Local anesthetic + Antifungal |
| Route of Administration | Otic (topical). |
| Storage | Store below 25ยฐC, protect from light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Lidocaine blocks sodium channels, inhibiting nerve impulse conduction. Clotrimazole inhibits fungal cytochrome P450 14ฮฑ-demethylase, disrupting ergosterol synthesis.
Mechanism Steps
๐ก How to Take c biotic ear drop
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of c biotic ear drop
โ Common Side Effects
- Local irritation
- Stinging
- Burning
๐จ Serious Side Effects
- Allergic reaction
- Ototoxicity (if tympanic membrane perforated)
โ ๏ธ Rare Side Effects
- Systemic lidocaine toxicity (very rare with topical use)
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Class I antiarrhythmics | Major | Additive cardiac toxicity |
| Cimetidine | Major | Increased lidocaine levels |
| Ketoconazole | Major | Increased lidocaine levels |
| Beta-blockers | Moderate | Reduced lidocaine clearance |
| Rifampin | Moderate | Decreased lidocaine levels |
| Phenytoin | Moderate | Decreased lidocaine levels |
๐จ Major Interactions
- Class I antiarrhythmics
- CYP1A2 inhibitors (e.g., cimetidine)
- CYP3A4 inhibitors (e.g., ketoconazole)
โก Moderate Interactions
- Beta-blockers
- CYP1A2 inducers (e.g., rifampin)
- CYP3A4 inducers (e.g., phenytoin)
โน๏ธ Minor Interactions
- Other topical otologicals
๐ฝ๏ธ Food Interactions
None known.
๐ท Alcohol Interaction
No significant interaction.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to lidocaine, clotrimazole, or any component; perforated tympanic membrane.
๐ Monitoring Parameters
Signs of local irritation, allergic reaction, or systemic toxicity.
๐คฑ Lactation Safety
Lidocaine excreted in breast milk; use with caution. Clotrimazole unlikely to be absorbed.
๐ Overdose Management
Systemic overdose unlikely; if occurs, treat symptomatically (e.g., CNS depression, arrhythmias).
โฐ Missed Dose
Apply as soon as remembered; skip if almost time for next dose.