brutal tablet - Albendazole (400mg) + Levamisole (150mg) medicine

brutal tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Endocard India Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
โš ๏ธ Hepatotoxicity Risk ๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is brutal tablet used for?

Brutal Tablet (Albendazole + Levamisole) is used to treat ANTI INFECTIVES. It contains Albendazole (400mg) + Levamisole (150mg), which Albendazole: inhibits microtubule synthesis; Levamisole: nicotinic acetylcholine. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Albendazole + Levamisole
  • Manufacturer: Endocard India Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š brutal tablet Uses & Benefits

Helminth infections (e.g., hookworm, roundworm)

Off-label uses: Neurocysticercosis (albendazole alone)

๐Ÿ“‹ Drug Information

Generic Name(s)Albendazole + Levamisole
Brand NameBrutal Tablet
ManufacturerEndocard India Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassAnthelmintic
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionAlbendazole: poorly absorbed orally; Levamisole: rapidly absorbed orally
DistributionAlbendazole: widely distributed; Levamisole: distributed to tissues
Protein BindingAlbendazole: 70%; Levamisole: 20-30%
MetabolismAlbendazole: hepatic to albendazole sulfoxide; Levamisole: hepatic
Half-LifeAlbendazole: 8-12 hours; Levamisole: 4-6 hours
ExcretionAlbendazole: renal and biliary; Levamisole: renal
BioavailabilityAlbendazole: <5% (increased with fatty meal); Levamisole: >90%
Onset of ActionWithin hours
Peak Plasma TimeAlbendazole: 2-4 hours; Levamisole: 1-2 hours
Duration of Action24-48 hours

How It Works

Albendazole: inhibits microtubule synthesis; Levamisole: nicotinic acetylcholine receptor agonist

Mechanism Steps

1Albendazole binds to beta-tubulin, inhibiting microtubule polymerization
2Disrupts glucose uptake and energy metabolism in helminths
3Levamisole acts as a nicotinic acetylcholine receptor agonist

๐Ÿ’ก How to Take brutal tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of brutal tablet

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Abdominal pain
  • Headache
  • Dizziness

๐Ÿšจ Serious Side Effects

  • Hepatotoxicity
  • Bone marrow suppression
  • Seizures

โš ๏ธ Rare Side Effects

  • Stevens-Johnson syndrome
  • Agranulocytosis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Cimetidine Major Increased albendazole levels
Dexamethasone Major Increased albendazole levels
Praziquantel Major Increased praziquantel levels
Theophylline Moderate Increased theophylline levels
Warfarin Moderate Increased anticoagulant effect
Alcohol Minor Increased hepatotoxicity risk

๐Ÿšจ Major Interactions

  • Cimetidine
  • Dexamethasone
  • Praziquantel

โšก Moderate Interactions

  • Theophylline
  • Warfarin

โ„น๏ธ Minor Interactions

  • Alcohol

๐Ÿฝ๏ธ Food Interactions

Fatty meal increases albendazole absorption

๐Ÿท Alcohol Interaction

Avoid alcohol; may increase hepatotoxicity risk

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity, pregnancy, hepatic impairment

๐Ÿ“Š Monitoring Parameters

Liver function tests, blood counts

๐Ÿคฑ Lactation Safety

Not recommended; excreted in milk

๐Ÿ’Š Overdose Management

Gastric lavage, supportive care

โฐ Missed Dose

Take as soon as remembered; skip if near next dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

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