brumica 50mg injection
What is brumica 50mg injection used for?
Brumica (Micafungin) is used to treat ANTI INFECTIVES. It contains Micafungin (50mg), which Inhibits the synthesis of 1,3-beta-D-glucan, an essential component of fungal ce. Always consult your doctor before use. Take as prescribed.
- Generic Name: Micafungin
- Manufacturer: Brawn Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ brumica 50mg injection Uses & Benefits
Treatment of candidemia, esophageal candidiasis, invasive aspergillosis (refractory or intolerant to other therapy), prophylaxis of Candida infections in hematopoietic stem cell transplant recipients.
Off-label uses: Treatment of urinary tract infections due to Candida, Empiric therapy for febrile neutropenia
๐ Drug Information
| Generic Name(s) | Micafungin |
| Brand Name | Brumica |
| Manufacturer | Brawn Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Fungal cell wall synthesis inhibitor (Echiocandins) |
| Route of Administration | Intravenous infusion over 1 hour. |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light. Reconstituted solution stable for 24 hours at room temperature. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits the synthesis of 1,3-beta-D-glucan, an essential component of fungal cell walls, leading to cell lysis and death.
Mechanism Steps
๐ก How to Take brumica 50mg injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of brumica 50mg injection
โ Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Headache
- Phlebitis
- Hypokalemia
- Pyrexia
๐จ Serious Side Effects
- Hepatotoxicity
- Anaphylaxis
- Hemolytic anemia
- Renal impairment
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Thrombocytopenia
- Leukopenia
- Pancreatitis
- Seizures
- Cardiac arrhythmias
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Sirolimus | Major | Increased sirolimus levels; monitor sirolimus concentrations. |
| Nifedipine | Major | Increased nifedipine levels; monitor for toxicity. |
| Itraconazole | Major | Increased itraconazole levels; monitor for adverse effects. |
| Cyclosporine | Moderate | Increased cyclosporine levels; monitor renal function and cyclosporine levels. |
| Tacrolimus | Moderate | Increased tacrolimus levels; monitor tacrolimus concentrations. |
| Voriconazole | Moderate | Possible additive hepatotoxicity; monitor liver function. |
| Rifampin | Minor | Possible decreased micafungin levels; clinical significance unclear. |
| Phenytoin | Minor | Possible decreased micafungin levels; clinical significance unclear. |
| Carbamazepine | Minor | Possible decreased micafungin levels; clinical significance unclear. |
๐จ Major Interactions
- Sirolimus
- Nifedipine
- Itraconazole
โก Moderate Interactions
- Cyclosporine
- Tacrolimus
- Voriconazole
โน๏ธ Minor Interactions
- Rifampin
- Phenytoin
- Carbamazepine
๐ฝ๏ธ Food Interactions
No significant food interactions; administered intravenously.
๐ท Alcohol Interaction
No known interaction.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to micafungin or any component of the formulation.
๐ Monitoring Parameters
Liver function tests (ALT, AST, bilirubin), renal function, complete blood count, signs of infusion reactions.
๐คฑ Lactation Safety
Not recommended; unknown if excreted in human milk.
๐ Overdose Management
No specific antidote; hemodialysis not effective. Supportive care.
โฐ Missed Dose
Administer as soon as possible; do not double dose. Resume normal schedule.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for brumica 50mg injection
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Medical Note: Always consult your doctor before switching medications.
โญ User Reviews
Found this to be a helpful product. Good results.
Found this to be a helpful product. Good results.
This medicine was effective for me. I followed the doctor's advice.
Found this to be a helpful product. Good results.
Good quality medicine. Satisfied with the outcome.