bro cef 1500mg injection - Cefuroxime (1500mg) medicine

bro cef 1500mg injection - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Biovista Lifesciences ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 22, 2026
โš ๏ธ Hepatotoxicity Risk ๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 22, 2026

What is bro cef 1500mg injection used for?

Altacef 500 Tablet (Cefuroxime) is used to treat ANTI INFECTIVES. It contains Cefuroxime (1500mg), which Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Cefuroxime
  • Manufacturer: Biovista Lifesciences
  • Form: Allopathy
  • Pregnancy Category: B
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š bro cef 1500mg injection Uses & Benefits

Upper and lower respiratory tract infections, urinary tract infections, skin and soft tissue infections, otitis media, sinusitis, gonorrhea, Lyme disease.

Off-label uses: Prophylaxis for surgical infections, treatment of bone and joint infections.

๐Ÿ“‹ Drug Information

Generic Name(s)Cefuroxime
Brand NameAltacef 500 Tablet
ManufacturerBiovista Lifesciences
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassCephalosporins: 2nd generation
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed after oral administration; food increases absorption.
DistributionDistributes widely into body tissues and fluids, including pleural fluid, synovial fluid, bone, and CSF (when meninges inflamed).
Protein Binding33-50%
MetabolismNot significantly metabolized; primarily renal excretion.
Half-Life1-2 hours
ExcretionRenal (80-90% unchanged in urine within 24 hours)
BioavailabilityApproximately 37% (oral); increased with food.
Onset of ActionRapid; within 1 hour for most infections.
Peak Plasma Time2-3 hours (oral)
Duration of ActionApproximately 8-12 hours

How It Works

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), inhibiting transpeptidase and autolysin activity.

Mechanism Steps

1Cefuroxime binds to penicillin-binding proteins (PBPs) on bacterial cell wall.
2Inhibits transpeptidase enzyme, preventing cross-linking of peptidoglycan chains.
3Activates autolytic enzymes (autolysins) leading to cell wall lysis.

๐Ÿ’ก How to Take bro cef 1500mg injection

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of bro cef 1500mg injection

โœ… Common Side Effects

  • Diarrhea
  • Nausea
  • Vomiting
  • Rash
  • Injection site reactions (if IV)

๐Ÿšจ Serious Side Effects

  • Severe allergic reactions (anaphylaxis)
  • Clostridioides difficile diarrhea
  • Seizures (high doses)
  • Stevens-Johnson syndrome

โš ๏ธ Rare Side Effects

  • Hemolytic anemia
  • Interstitial nephritis
  • Hepatitis
  • Agranulocytosis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Probenecid Major Decreased renal excretion of cefuroxime, increased levels
Live typhoid vaccine Major Reduced vaccine efficacy
BCG vaccine Major Reduced vaccine efficacy
Loop diuretics Moderate Increased nephrotoxicity risk
Aminoglycosides Moderate Increased nephrotoxicity risk
Oral contraceptives Moderate Reduced contraceptive efficacy
Antacids Minor Decreased absorption of cefuroxime
H2 antagonists Minor Decreased absorption of cefuroxime
Proton pump inhibitors Minor Decreased absorption of cefuroxime

๐Ÿšจ Major Interactions

  • Warfarin
  • Probenecid
  • Live typhoid vaccine
  • BCG vaccine

โšก Moderate Interactions

  • Loop diuretics
  • Aminoglycosides
  • Oral contraceptives
  • BCG (intravesical)

โ„น๏ธ Minor Interactions

  • Antacids
  • H2 antagonists
  • Proton pump inhibitors

๐Ÿฝ๏ธ Food Interactions

Food increases absorption; take with food.

๐Ÿท Alcohol Interaction

No known interaction; but may increase risk of disulfiram-like reaction (rare).

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to cefuroxime or other cephalosporins; previous immediate hypersensitivity reaction to penicillins.

๐Ÿ“Š Monitoring Parameters

Renal function, signs of hypersensitivity, superinfection, bleeding (if on warfarin).

๐Ÿคฑ Lactation Safety

Excreted in breast milk in small amounts; generally considered compatible with breastfeeding.

๐Ÿ’Š Overdose Management

Supportive care; hemodialysis may enhance elimination.

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose and resume regular schedule. Do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 22, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for bro cef 1500mg injection

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Alternative brands with exact same active ingredient (Cefuroxime (1500mg)):

Medical Note: Always consult your doctor before switching medications.

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