blisderms ointment - Halobetasol (0.05% w/w) + Salicylic Acid (3% w/w) medicine

Blisderms Ointment - Uses, Price, Side Effects

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🏭 Johnson & Johnson Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

What is blisderms ointment used for?

Blisderms Ointment is a combination of Halobetasol (a potent corticosteroid) and Salicylic Acid (a keratolytic agent) used to treat inflammatory skin conditions like psoriasis and eczema. Halobetasol reduces inflammation and itching, while salicylic acid helps remove scales and soften skin, allowing better penetration of the steroid.

  • Generic Name: Halobetasol + Salicylic Acid
  • Manufacturer: Johnson & Johnson Ltd
  • Form: Allopathy
  • Pregnancy Category: Category A
  • Prescription Required: Yes
💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 blisderms ointment Uses & Benefits

Psoriasis, eczema, dermatitis, lichen planus, other steroid-responsive dermatoses with hyperkeratosis

Off-label uses: Ichthyosis, Keratoderma, Calluses

📋 Drug Information

Generic Name(s)Halobetasol + Salicylic Acid
Brand NameAbihalo Ointment
ManufacturerJohnson & Johnson Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassCorticosteroid + Keratolytic
Route of AdministrationTopical
StorageStore at 20-25°C (68-77°F); keep tightly closed
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionTopical absorption varies; enhanced by salicylic acid
DistributionPrimarily local; minimal systemic distribution
Protein BindingHalobetasol: >90% bound to plasma proteins
MetabolismHalobetasol: Hepatic via CYP3A4; Salicylic Acid: Hepatic conjugation
Half-LifeHalobetasol: ~5-6 hours; Salicylic Acid: 2-3 hours (dose-dependent)
ExcretionRenal (metabolites) and fecal
BioavailabilityMinimal systemic absorption with topical use
Onset of ActionWithin a few days
Peak Plasma TimeNot applicable for topical use
Duration of ActionSeveral hours to days depending on application

How It Works

Halobetasol: Anti-inflammatory, immunosuppressive; Salicylic Acid: Keratolytic, desmolytic

Mechanism Steps

1Halobetasol binds to glucocorticoid receptor
2Complex translocates to nucleus
3Modulates gene transcription
4Inhibits phospholipase A2
5Reduces prostaglandin and leukotriene synthesis
6Suppresses cytokine production
7Salicylic acid dissolves intercellular cement
8Promotes desquamation of corneocytes

💡 How to Take blisderms ointment

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

⚠️ Side Effects of blisderms ointment

✅ Common Side Effects

Burning
itching
irritation
dryness
folliculitis
hypertrichosis
acneiform eruptions
hypopigmentation
perioral dermatitis
allergic contact dermatitis
maceration
secondary infection
skin atrophy
striae
miliaria

🚨 Serious Side Effects

Adrenal suppression
Cushing's syndrome
hyperglycemia
glaucoma
cataracts
salicylate toxicity (tinnitus, metabolic acidosis)

⚠️ Rare Side Effects

Kaposi's sarcoma
osteoporosis
growth retardation in children

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Moderate Increased risk of bleeding due to salicylic acid
Methotrexate Major Increased methotrexate toxicity
Aspirin Moderate Additive salicylate toxicity
NSAIDs Moderate Increased gastrointestinal irritation

🚨 Major Interactions

  • CYP3A4 inhibitors
  • Anticoagulants

⚡ Moderate Interactions

  • Aspirin
  • NSAIDs
  • Methotrexate

🍷 Alcohol Interaction

No known interaction

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to components, viral skin infections, fungal infections, skin ulcers, rosacea, perioral dermatitis

🤱 Lactation Safety

Caution; avoid application to breast area

💊 Overdose Management

Discontinue use; symptomatic treatment; monitor for systemic effects

⏰ Missed Dose

Apply as soon as remembered; skip if almost time for next dose

🔄 Substitutes for blisderms ointment

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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