bivir tablet - Uses, Price, Side Effects & Substitutes
What is bivir tablet used for?
Acivir 400 DT Tablet (Acyclovir) is used to treat ANTI INFECTIVES. It contains Acyclovir (200mg), which Acyclovir is converted to acyclovir monophosphate by viral thymidine kinase, the. Always consult your doctor before use. Take as prescribed.
- Generic Name: Acyclovir
- Manufacturer: Prayas Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: B
- Prescription Required: Yes
๐ bivir tablet Uses & Benefits
Herpes simplex infections (genital, oral, encephalitis), varicella-zoster (chickenpox, shingles).
Off-label uses: Herpes simplex prophylaxis in immunocompromised, EBV infection
๐ Drug Information
| Generic Name(s) | Acyclovir |
| Brand Name | Acivir 400 DT Tablet |
| Manufacturer | Prayas Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Antiviral (Non-HIV) drugs |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Acyclovir is converted to acyclovir monophosphate by viral thymidine kinase, then to triphosphate by cellular kinases, which inhibits viral DNA polymerase and incorporates into viral DNA, causing chain termination.
Mechanism Steps
๐ก How to Take bivir tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of bivir tablet
โ Common Side Effects
- Nausea
- Diarrhea
- Headache
- Dizziness
- Fatigue
๐จ Serious Side Effects
- Acute renal failure
- Neurotoxicity (confusion, hallucinations, seizures)
- Thrombotic thrombocytopenic purpura/hemolytic uremic syndrome (TTP/HUS)
โ ๏ธ Rare Side Effects
- Hepatitis
- Stevens-Johnson syndrome
- Anaphylaxis
- Leukopenia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Probenecid | Major | Reduced renal clearance of acyclovir, increased plasma levels and toxicity risk. |
| Cimetidine | Major | Increased acyclovir AUC and half-life. |
| Mycophenolate mofetil | Major | Increased plasma levels of both drugs; monitor for toxicity. |
| Tenofovir | Moderate | Additive nephrotoxicity risk. |
| Aminoglycosides | Moderate | Increased risk of nephrotoxicity. |
| Cyclosporine | Moderate | Increased nephrotoxicity risk. |
| Tacrolimus | Moderate | Increased nephrotoxicity risk. |
| Zidovudine | Minor | Possible increased drowsiness. |
| Interferon | Minor | Possible additive antiviral effect. |
๐จ Major Interactions
- Probenecid
- Cimetidine
- Mycophenolate mofetil
โก Moderate Interactions
- Tenofovir
- Aminoglycosides
- Cyclosporine
- Tacrolimus
โน๏ธ Minor Interactions
- Zidovudine
- Interferon
๐ฝ๏ธ Food Interactions
No significant food interactions; may be taken with or without food.
๐ท Alcohol Interaction
No known interaction; however, alcohol may exacerbate side effects like dizziness.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to acyclovir or valacyclovir.
๐ Monitoring Parameters
Renal function (especially in elderly or high-dose therapy); hydration status.
๐คฑ Lactation Safety
Caution; acyclovir is excreted in breast milk but considered compatible with breastfeeding.
๐ Overdose Management
Supportive care; hemodialysis may enhance elimination.
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for bivir tablet
View AllAlternative brands with exact same active ingredient (Acyclovir (200mg)):
-
glenvirax 200mg tabletGlenmark Pharmaceuticals Ltd โน16.88 66.8% CHEAPER
-
clovirax 200mg tablet dtManeesh Pharmaceuticals Ltd โน34.00 33.2% CHEAPER
-
okavir 200mg tablet dtCipla Ltd โน34.00 33.2% CHEAPER
-
herperax tabletMicro Labs Ltd โน39.95 21.5% CHEAPER
-
zovirax 200 tabletGlaxo SmithKline Pharmaceuticals Ltd โน40.60 20.2% CHEAPER
-
acicet 200mg tablet dtKivi Labs Ltd โน46.43 8.8% CHEAPER
-
acyclor 200mg tabletTalent Healthcare โน46.88 7.9% CHEAPER
-
virex 200mg tabletBDH Industries Ltd โน49.69 2.4% CHEAPER
-
optiviral 200mg tabletEntod Pharmaceuticals Ltd โน50.63 0.5% CHEAPER
-
aclovir 200mg tabletInd Swift Laboratories Ltd โน51.56 1.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.