Itraconazole 200 mg Capsule: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Yellowing of skin or eyes (jaundice)
- Dark urine or pale stools
- Severe abdominal pain or swelling
- Shortness of breath or difficulty breathing
- Swelling of face, lips, or throat
- Rapid or irregular heartbeat
- Sudden weight gain or swelling of ankles
- Numbness or tingling in hands or feet
- Ringing in ears or hearing loss
- Severe skin rash with fever
If experiencing severe symptoms, call emergency services immediately.
What is biotraz 200mg capsule used for?
This medicine is an antifungal capsule containing itraconazole 200 mg. It treats systemic fungal infections by disrupting fungal cell membranes. Take it with food, avoid alcohol, and follow your doctor's instructions carefully.
- Generic Name: Itraconazole
- Manufacturer: Bioworld Pharma
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 biotraz 200mg capsule के बारे में (Hindi Summary)
उपयोग: यह दवा इट्राकोनाज़ोल 200 मिलीग्राम कैप्सूल है, जो एक एंटीफंगल दवा है। यह शरीर में फंगल संक्रमण के इलाज के लिए इस्तेमाल की जाती है, जैसे कि ब्लास्टोमाइकोसिस, हिस्टोप्लाज्मोसिस, एस्परगिलोसिस, और नाखूनों के फंगल संक्रमण। यह दवा फंगस की कोशिका झिल्ली को नष्ट करके उन्हें मार देती है। इसे भोजन के साथ लेना चाहिए। इसका सेवन डॉक्टर के निर्देशानुसार ही करें।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द, सिरदर्द और दाने शामिल हैं। गंभीर दुष्प्रभावों में लिवर की क्षति (पीलिया, गहरे रंग का पेशाब, थकान), हृदय विफलता (सूजन, सांस लेने में कठिनाई), और गंभीर एलर्जी प्रतिक्रिया (चेहरे, होंठ या गले में सूजन, सांस लेने में कठिनाई) शामिल हैं। यदि आपको कोई भी गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे भोजन के साथ लें। एंटासिड या एसिड कम करने वाली दवाओं के साथ इसे 2 घंटे के अंतराल पर लें। शराब का सेवन न करें। अपने डॉक्टर को अपनी सभी दवाओं के बारे में बताएं। लिवर की जांच करवाते रहें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर से सलाह लें।
💊 biotraz 200mg capsule Uses & Benefits
[{"condition":"Blastomycosis","description":"Treatment of pulmonary and extrapulmonary blastomycosis caused by Blastomyces dermatitidis.","evidence":"Well-established"},{"condition":"Histoplasmosis","description":"Treatment of chronic pulmonary or disseminated histoplasmosis in immunocompromised patients.","evidence":"Well-established"},{"condition":"Aspergillosis","description":"Treatment of invasive aspergillosis in patients who are intolerant to amphotericin B.","evidence":"Well-established"},{"condition":"Onychomycosis","description":"Treatment of fungal nail infections caused by dermatophytes and yeasts.","evidence":"Well-established"},{"condition":"Mucosal candidiasis","description":"Treatment of oropharyngeal and esophageal candidiasis that is refractory to fluconazole.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Coccidioidomycosis","description":"May be used off-label for treatment of coccidioidomycosis in patients who cannot tolerate other antifungals.","evidence":"Limited"},{"condition":"Paracoccidioidomycosis","description":"Occasionally used off-label for paracoccidioidomycosis, a fungal infection common in Latin America.","evidence":"Limited"}]
Primary treatment for: Fungal infections
Also treats: Blastomycosis, Histoplasmosis, Aspergillosis, Onychomycosis, Mucosal candidiasis
📋 Drug Information
| Generic Name(s) | Itraconazole |
| Brand Name | Alcros 100 Capsule |
| Manufacturer | Bioworld Pharma |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OPHTHAL |
| Action Class | Fungal ergosterol synthesis inhibitor |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from moisture and heat. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by inhibiting the fungal cytochrome P450 enzyme 14α-demethylase, which is responsible for converting lanosterol to ergosterol. Ergosterol is a critical component of the fungal cell membrane. Without ergosterol, the fungal cell membrane becomes weak and permeable, leading to leakage of cellular contents and ultimately cell death. This medicine is fungistatic at lower concentrations and fungicidal at higher concentrations, depending on the fungal species and drug concentration.
Mechanism Steps
💡 How to Take biotraz 200mg capsule
Strength: Capsule, 200 mg
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 200 mg taken orally once daily, but the exact dose and duration depend on the type and severity of the fungal infection. For onychomycosis, a pulse dosing regimen of 200 mg twice daily for one week per month for 2 to 3 months may be used. For systemic infections, the dose may be 200 mg once daily for several weeks to months. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine. Dose selection should be cautious, and liver and kidney function should be monitored. No specific dose adjustment is recommended solely based on age, but individualization is advised. |
| Renal Impairment | In patients with mild to moderate renal impairment, no dose adjustment is necessary. In severe renal impairment (creatinine clearance <30 mL/min), this medicine should be used with caution; dose reduction may be considered based on clinical response and tolerability. |
| Hepatic Impairment | In patients with hepatic impairment, this medicine should be used with caution. Dose reduction may be necessary. Liver function should be monitored closely. Avoid use in patients with severe hepatic impairment unless the benefit outweighs the risk. |
| Maximum Daily Dose | The maximum recommended daily dose is 400 mg per day, but this should only be used under strict medical supervision for specific indications. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of biotraz 200mg capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Cisapride | Major | |
| Pimozide | Major | |
| Quinidine | Major | |
| Methadone | Major | |
| Simvastatin | Major | |
| Warfarin | Moderate | |
| Digoxin | Moderate | |
| Phenytoin | Moderate | |
| Rifampin | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Cisapride
- Pimozide
- Quinidine
- Methadone
- Disopyramide
- Dofetilide
- Levodopa
- Midazolam
- Triazolam
- HMG-CoA reductase inhibitors (statins)
⚡ Moderate Interactions
- Warfarin
- Digoxin
- Phenytoin
- Rifampin
- Rifabutin
- Carbamazepine
- Phenobarbital
- Isoniazid
- Clarithromycin
- Erythromycin
🍷 Alcohol Interaction
Avoid consuming alcohol while taking this medicine. Alcohol can increase the risk of liver damage and may worsen side effects such as nausea and dizziness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to itraconazole or other azole antifungals","Concurrent use with cisapride, pimozide, quinidine, dofetilide, or levomethadyl","Concurrent use with methadone","Concurrent use with disopyramide","Concurrent use with simvastatin or lovastatin","Concurrent use with triazolam or oral midazolam","Pregnancy (except in life-threatening infections)","Ventricular dysfunction or history of heart failure"]
⚠️ Warnings & Precautions
["This medicine should be taken with food to ensure adequate absorption.","Do not use in patients with evidence of ventricular dysfunction or heart failure.","Monitor liver function closely; discontinue if signs of liver injury occur.","Avoid concurrent use with drugs that prolong QT interval.","Use with caution in patients with renal impairment; dose adjustment may be needed.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Do not share this medicine with others, even if they have similar symptoms.","Keep out of reach of children."]
🤱 Lactation Safety
This medicine is excreted in human breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
💊 Overdose Management
In case of overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if ingestion is recent. Monitor vital signs and cardiac function. Contact a poison control center for guidance.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not take more or less than the recommended dose. Swallow the capsule whole with a full glass of water, preferably with a meal. Avoid taking antacids or acid-reducing medicines within 2 hours of taking this medicine, as they can reduce its absorption. Do not drink alcohol while taking this medicine, as it may increase the risk of liver problems. Inform your doctor about all other medicines you are taking, especially blood thinners, heart medications, and other antifungals. Your doctor may monitor your liver function with blood tests before and during treatment. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose. Store this medicine at room temperature away from moisture and heat. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to side effects such as liver toxicity and heart failure. Close monitoring of liver and cardiac function is advised. Dose adjustment may be necessary based on renal and hepatic function.
🤰 Pregnancy Planning (TTC)
This medicine should be avoided during pregnancy and in women planning to become pregnant. Use effective contraception during treatment and for at least 2 months after the last dose. Consult your doctor if you are planning pregnancy.
🏥 Post-Surgery Considerations
If you are undergoing surgery, inform your surgeon and anesthesiologist that you are taking this medicine, as it can interact with anesthetic agents and other medications. It may need to be temporarily stopped before surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It may interact with medications used during dental work, and there is a risk of bleeding if you are also on blood thinners.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness or fatigue. Avoid strenuous exercise if you feel unwell. Consult your doctor before starting any new exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or blurred vision in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe to continue your daily activities, but take precautions if you experience side effects.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. Complete the full prescribed course even if symptoms improve. If you experience serious side effects, contact your doctor immediately; they may advise you to stop.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of liver toxicity, heart failure, and peripheral neuropathy. Regular monitoring of liver function and cardiac status is recommended. Prolonged use may also lead to fungal resistance. Use the lowest effective dose for the shortest duration necessary.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
For mild skin and nail infections, topical creams or lacquers may be sufficient.
Evidence: Well-establishedFluconazole or terbinafine may be alternatives depending on the infection.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you are immunocompromised, discuss vaccination timing with your doctor.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from moisture and heat. If crossing time zones, continue taking it at the same interval as prescribed, but consult your doctor for specific advice. Keep it in your carry-on luggage to avoid loss or temperature extremes.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Improvement may be seen within a few days to weeks, depending on the infection. Complete treatment as prescribed.
A: Yes, take it with a full meal to improve absorption and reduce stomach upset.
A: Serious side effects include liver damage, heart failure, and severe allergic reactions. Seek immediate medical help if you experience symptoms like yellowing of eyes, swelling, or difficulty breathing.
A: It is not recommended during pregnancy except in life-threatening infections. Consult your doctor.
A: No, avoid alcohol as it increases the risk of liver toxicity.
🤔 Common Patient Concerns
🔄 Substitutes for biotraz 200mg capsule
View AllAlternative brands with exact same active ingredient:
-
itrazeal 200mg capsuleGlantis Pharmaceutical ₹20.63 85.3% CHEAPER
-
itrapro 200mg capsuleKitnix Pvt Ltd ₹33.98 75.7% CHEAPER
-
davaindia itraconazole 200mg capsuleDavaindia Generic Pharmacy ₹39.38 71.9% CHEAPER
-
fungizee 200 capsuleZeelab Pharmacy Pvt Ltd ₹40.00 71.4% CHEAPER
-
candimore 200mg capsuleMorepen Laboratories Ltd ₹45.00 67.9% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any fungal infection quickly.
Fact: This medicine is effective for specific fungal infections and requires a full course of treatment. It does not work for all types of fungi. - Myth: You can stop taking this medicine as soon as symptoms improve.
Fact: You must complete the full prescribed course to prevent recurrence and resistance. - Myth: This medicine is safe to take with any other medication.
Fact: This medicine interacts with many drugs. Always inform your doctor about all medicines you take.
🔄 Alternative Options
Generic Alternatives
- Itraconazole
Brand Alternatives
- Candiforce 200
- Itrasys 200
- Sporanox 200