Amloz L Tablet: A Comprehensive Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, tongue, or throat
- Difficulty breathing or swallowing
- Severe dizziness or fainting
- Chest pain or irregular heartbeat
- Decreased urine output or swelling in legs
- Severe abdominal pain or yellowing of eyes
- Muscle weakness or cramps
If experiencing severe symptoms, call emergency services immediately.
What is biopril am 5 mg/5 mg tablet used for?
This medicine is a combination of Amlodipine and Lisinopril used to treat high blood pressure. It works by relaxing blood vessels and reducing the workload on the heart. It is taken orally once daily, usually in the morning. Do not stop taking it without consulting your doctor.
- Generic Name: Amlodipine (5mg) + Lisinopril (5mg)
- Manufacturer: Biochem Pharmaceutical Industries
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 biopril am 5 mg/5 mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा उच्च रक्तचाप (हाइपरटेंशन) के इलाज के लिए इस्तेमाल की जाती है। इसमें एम्लोडिपिन और लिसिनोप्रिल दो दवाएं होती हैं जो रक्त वाहिकाओं को आराम देकर और हृदय पर दबाव कम करके रक्तचाप को नियंत्रित करती हैं। यह दवा दिल के दौरे और स्ट्रोक के खतरे को कम करने में मदद करती है। इसे रोजाना एक बार लेना चाहिए, आमतौर पर सुबह के समय। डॉक्टर की सलाह के बिना इसे बंद न करें।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में चक्कर आना, सिरदर्द, थकान, और सूखी खांसी शामिल हैं। कुछ लोगों में पैरों में सूजन भी हो सकती है। गंभीर दुष्प्रभावों में चेहरे, होंठ, जीभ या गले में सूजन (एंजियोएडेमा) शामिल है, जो एक आपातकालीन स्थिति है। अगर ऐसा हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। शराब से बचें क्योंकि इससे चक्कर आ सकते हैं। अचानक उठने से बचें। गर्भावस्था के दौरान इस दवा का सेवन न करें। पोटैशियम सप्लीमेंट लेने से पहले डॉक्टर से सलाह लें। दर्द निवारक दवाओं (जैसे इबुप्रोफेन) का सेवन बिना डॉक्टर की सलाह के न करें। नियमित रूप से रक्तचाप और किडनी की जांच कराते रहें।
💊 biopril am 5 mg/5 mg tablet Uses & Benefits
[{"condition":"Essential Hypertension","description":"This medicine is used to lower high blood pressure when monotherapy is insufficient or as initial combination therapy in patients likely to need multiple agents.","evidence":"Well-established"},{"condition":"Hypertension with comorbid conditions","description":"May be particularly useful in patients with hypertension and heart failure, post-myocardial infarction, or diabetic nephropathy due to the ACE inhibitor component.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Not established from the available information.","description":"Not established from the available information.","evidence":"Not established from the available information."}]
Primary treatment for: Hypertension
Also treats: Heart failure, Diabetic nephropathy, Post-myocardial infarction
📋 Drug Information
| Generic Name(s) | Amlodipine (5mg) + Lisinopril (5mg) |
| Brand Name | biopril am 5 mg/5 mg tablet |
| Manufacturer | Biochem Pharmaceutical Industries |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antihypertensive agents with complementary mechanisms. Amlodipine is a dihydropyridine calcium channel blocker that inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle. This leads to relaxation of vascular smooth muscle, reducing peripheral vascular resistance and lowering blood pressure. Lisinopril is a competitive inhibitor of angiotensin-converting enzyme (ACE), preventing the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor. This results in decreased aldosterone secretion, reduced sodium and water retention, and lowered blood pressure. The combination provides additive blood pressure reduction.
Mechanism Steps
💡 How to Take biopril am 5 mg/5 mg tablet
Strength: Amlodipine 5 mg + Lisinopril 5 mg immediate-release tablet.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally once daily, with or without food. The dose may be adjusted by your doctor based on your blood pressure response and tolerability. The maximum recommended dose is typically 10 mg Amlodipine and 40 mg Lisinopril per day, but this combination is available in fixed strengths. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the blood pressure-lowering effects of this medicine. Start with a lower dose and monitor closely for hypotension and renal function. Dose adjustments may be necessary. |
| Renal Impairment | In patients with renal impairment, Lisinopril dose may need to be reduced. For creatinine clearance less than 30 mL/min, the initial dose of Lisinopril should be reduced. Amlodipine is generally safe but monitor for edema. Consult your doctor for individualized dosing. |
| Hepatic Impairment | In patients with hepatic impairment, Amlodipine should be started at a lower dose and titrated slowly. Lisinopril does not require adjustment but monitor for hypotension. Consult your doctor. |
| Maximum Daily Dose | The maximum daily dose of this combination is typically one tablet of the highest available strength (e.g., Amlodipine 10 mg + Lisinopril 40 mg) once daily. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of biopril am 5 mg/5 mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Potassium supplements | Major | |
| NSAIDs | Major | |
| Lithium | Major | |
| Diuretics | Moderate | |
| Other antihypertensives | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Potassium supplements or potassium-sparing diuretics
- NSAIDs (e.g., ibuprofen, naproxen)
- Lithium
⚡ Moderate Interactions
- Diuretics
- Other antihypertensives
🍷 Alcohol Interaction
Alcohol may enhance the blood pressure-lowering effect of this medicine, leading to dizziness, lightheadedness, and fainting. It is advisable to avoid or limit alcohol consumption while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["History of angioedema related to ACE inhibitors","Bilateral renal artery stenosis","Pregnancy","Severe aortic stenosis","Cardiogenic shock","Hypersensitivity to Amlodipine or Lisinopril"]
⚠️ Warnings & Precautions
["Avoid use in pregnancy; can cause fetal harm.","Monitor potassium levels; risk of hyperkalemia.","May cause symptomatic hypotension, especially after first dose.","Risk of angioedema; discontinue immediately if suspected.","Use with caution in patients with renal impairment.","Avoid abrupt discontinuation; may cause rebound hypertension.","Use with caution in patients with hepatic impairment.","May impair ability to drive or operate machinery; avoid until you know how it affects you."]
🤱 Lactation Safety
Amlodipine is excreted in human milk at low levels. Lisinopril is also excreted in breast milk. Due to the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or the drug, taking into account the importance of the drug to the mother. Consult your doctor.
💊 Overdose Management
Overdose may cause severe hypotension, dizziness, and electrolyte imbalances. Treatment is supportive and symptomatic. If overdose is suspected, contact a poison control center or emergency room immediately. Gastric lavage may be considered if ingestion is recent. Monitor blood pressure, heart rate, and electrolytes. Hemodialysis is not effective for removing Amlodipine; Lisinopril can be removed by hemodialysis.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Always take this medicine exactly as prescribed by your doctor. Do not stop or change the dose without consulting your healthcare provider, as abrupt discontinuation can lead to rebound hypertension. Avoid alcohol, as it can enhance the blood pressure-lowering effect and cause dizziness. Stand up slowly from a sitting or lying position to prevent dizziness due to low blood pressure. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding, as this medicine can harm the developing fetus. Do not use potassium supplements or salt substitutes containing potassium without your doctor's approval, as this can lead to dangerously high potassium levels. Avoid taking nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen without consulting your doctor, as they can reduce the effectiveness of this medicine and increase the risk of kidney problems. Keep all appointments for blood pressure monitoring and laboratory tests. If you experience swelling of the face, lips, tongue, or difficulty breathing, seek emergency medical help immediately.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the blood pressure-lowering effects. Start with a lower dose and monitor closely for dizziness, falls, and kidney function. Regular follow-up is essential.
🤰 Pregnancy Planning (TTC)
This medicine is contraindicated in pregnancy. If you are planning pregnancy, consult your doctor to switch to a safer alternative before conception. Use effective contraception while on this medicine.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be temporarily stopped before surgery to avoid blood pressure fluctuations. Follow your doctor's instructions.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine, as it may affect blood pressure during dental procedures. Local anesthetics with epinephrine should be used with caution.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is encouraged, but avoid sudden strenuous activities, especially in hot weather, as they can cause dizziness or fainting due to low blood pressure. Stay hydrated and rise slowly after exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, especially when you first start taking it. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal activities once adjusted.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Abrupt discontinuation can cause rebound hypertension. If you experience serious side effects like angioedema, stop immediately and seek emergency care.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe and effective for managing hypertension. Regular monitoring of blood pressure, kidney function, and electrolytes is necessary. In some patients, long-term use may lead to mild kidney function changes or electrolyte imbalances. It is important to continue lifestyle modifications and attend regular follow-ups.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and weight loss can help lower blood pressure and may reduce the need for medication.
Evidence: Well-establishedIf side effects occur, your doctor may switch to ARBs, beta-blockers, or diuretics.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, always inform your healthcare provider about all medicines you take before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry your medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, consult your doctor about adjusting the timing of your dose. Carry enough supply for the entire trip plus extra in case of delays. Check local customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood pressure within 24 hours, but full effect may take 1 to 2 weeks. Regular monitoring is important.
A: Yes, it is often used in diabetic patients, but monitor blood sugar and kidney function regularly.
A: A dry cough is a common side effect of Lisinopril. If it bothers you, consult your doctor; they may switch you to a different medicine.
🤔 Common Patient Concerns
🔄 Substitutes for biopril am 5 mg/5 mg tablet
View AllAlternative brands with exact same active ingredient:
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lisi am 5mg/5mg tabletDavaindia Generic Pharmacy ₹18.00 61.8% CHEAPER
-
etopres lp 5 mg/5 mg tabletPsychotropics India Ltd ₹22.03 53.3% CHEAPER
-
inace 5 mg/5 mg tabletWin-Medicare Pvt Ltd ₹24.61 47.8% CHEAPER
-
zanlodi lp 5mg/5mg tabletZaneka Healthcare Pvt Ltd ₹26.25 44.4% CHEAPER
-
lismol 5 mg/5 mg tabletOrchid Chemicals & Pharmaceuticals Ltd ₹32.81 30.4% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be stopped once blood pressure is normal.
Fact: High blood pressure often has no symptoms, and stopping the medicine can cause a dangerous rebound. Continue as prescribed. - Myth: This medicine causes kidney damage in everyone.
Fact: While it can affect kidney function in some patients, regular monitoring helps prevent serious issues. The benefits usually outweigh the risks. - Myth: You can take this medicine only when you feel dizzy or have a headache.
Fact: This medicine must be taken regularly to control blood pressure, even if you feel fine.
🔄 Alternative Options
Generic Alternatives
- Amlodipine + Lisinopril generic tablets
Brand Alternatives
- Amlopres-L
- Amlong-L
- Stamlo-L