Cloben G Cream: Complete Medicine Guide for Patients
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, tongue, or throat, or difficulty breathing, which may indicate a severe allergic reaction.
- Severe burning, blistering, or peeling of the skin at the application site.
- Signs of worsening infection such as increased pain, heat, swelling, or pus from the treated area.
- Ringing in the ears or hearing difficulty, which may indicate neomycin toxicity.
- Decreased urine output or swelling of the legs, which may indicate kidney problems.
- Facial puffiness, unusual weight gain, or high blood sugar, which may indicate too much corticosteroid absorption.
- A new widespread rash or itching that spreads beyond the treated area.
If experiencing severe symptoms, call emergency services immediately.
What is biomycin cream used for?
This medicine is a topical cream containing beclometasone 0.025% w/w and neomycin 0.5% w/w. It is used to treat inflamed skin conditions that also have a bacterial infection, such as infected eczema or infected contact dermatitis. It reduces redness, swelling, and itching while killing the bacteria. Apply a thin layer to the affected skin only, as prescribed by your doctor, and do not use it for longer than recommended.
- Generic Name: Beclometasone + Neomycin
- Manufacturer: Biochem Pharmaceutical Industries
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 biomycin cream के बारे में (Hindi Summary)
उपयोग: यह दवा एक टॉपिकल क्रीम है जिसमें बेक्लोमेथासोन 0.025% w/w और नियोमाइसिन 0.5% w/w मौजूद होते हैं। यह त्वचा की उन समस्याओं के इलाज के लिए इस्तेमाल की जाती है जिनमें सूजन, लालिमा, खुजली के साथ-साथ बैक्टीरियल संक्रमण भी होता है, जैसे संक्रमित एक्जिमा या संक्रमित कॉन्टैक्ट डर्मेटाइटिस। बेक्लोमेथासोन सूजन और खुजली को कम करता है, जबकि नियोमाइसिन बैक्टीरिया को मारता है। इस क्रीम को केवल प्रभावित त्वचा पर पतली परत में लगाएं और डॉक्टर के बताए समय तक ही इस्तेमाल करें। इसे चेहरे, जांघों के बीच या बगल में बिना डॉक्टर की सलाह के न लगाएं।
साइड इफेक्ट्स: आम दुष्प्रभावों में लगाने की जगह पर हल्की जलन, खुजली, सूखापन या लालिमा शामिल हैं। ये आमतौर पर कुछ समय में ठीक हो जाते हैं। लंबे समय तक इस्तेमाल करने पर त्वचा पतली हो सकती है, खिंचाव के निशान पड़ सकते हैं या त्वचा का रंग बदल सकता है। नियोमाइसिन से कुछ लोगों को एलर्जी हो सकती है, जिसमें खुजली और लाल चकत्ते बढ़ जाते हैं। अगर कोई भी दुष्प्रभाव गंभीर हो या ठीक न हो, तो क्रीम लगाना बंद करें और डॉक्टर से मिलें।
सुरक्षा सलाह: इस क्रीम को केवल प्रभावित त्वचा पर और डॉक्टर के बताए अनुसार ही लगाएं। लगाने से पहले और बाद में हाथ धोएं, सिवाय इसके कि हाथ ही इलाज वाला हिस्सा हों। इलाज वाली जगह को प्लास्टिक या एयरटाइट पट्टी से न ढकें। आंखों, मुंह और नाक के संपर्क में न आने दें। चेहरे, जांघों के बीच या बगल में लंबे समय तक न लगाएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें और यह दवा किसी और के साथ साझा न करें।
💊 biomycin cream Uses & Benefits
[{"condition":"Infected eczema","description":"Reduces inflammation and itching while treating the bacterial infection that has developed on eczema patches.","evidence":"Well-established"},{"condition":"Infected contact dermatitis","description":"Helps calm the allergic skin reaction and controls secondary bacterial infection.","evidence":"Well-established"},{"condition":"Infected insect bite reactions","description":"Reduces swelling and itching from insect bites and prevents or treats infection from scratching.","evidence":"Commonly used"},{"condition":"Infected seborrheic dermatitis","description":"Controls inflammation and bacterial overgrowth on affected skin areas.","evidence":"Commonly used"},{"condition":"Localized bacterial skin infections with inflammation","description":"Used when a small area of skin has both infection and inflammatory changes.","evidence":"Commonly used"}]
Off-label uses: [{"condition":"Infected diaper rash","description":"Sometimes used for short periods in older infants and children when a doctor confirms bacterial infection along with inflammation.","evidence":"Limited"},{"condition":"Infected minor cuts or abrasions","description":"Occasionally applied to small superficial wounds with surrounding inflammation, but only under medical advice.","evidence":"Limited"}]
Primary treatment for: Infected inflammatory skin conditions such as infected eczema or infected contact dermatitis.
Also treats: Infected insect bite reactions, Infected seborrheic dermatitis, Localized bacterial skin infections with inflammation
📋 Drug Information
| Generic Name(s) | Beclometasone + Neomycin |
| Brand Name | Biomycin Cream |
| Manufacturer | Biochem Pharmaceutical Industries |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Macrolides |
| Route of Administration | Topical. This medicine is applied directly to the affected skin |
| Storage | Store at room temperature between 15°C and 30°C. Keep the tube tightly closed when not in use. Protect from direct sunlight and moisture. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the pack. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works through two complementary mechanisms. Beclometasone is a synthetic corticosteroid that binds to glucocorticoid receptors inside skin cells. This binding reduces the production of inflammatory chemicals such as prostaglandins and leukotrienes, calms immune cells in the skin, and narrows blood vessels, which decreases redness, swelling, and itching. Neomycin is an aminoglycoside antibiotic that enters bacterial cells and binds to the 30S ribosomal subunit. This binding causes the bacteria to make faulty proteins, which stops their growth and eventually kills them. The corticosteroid reduces inflammation, while the antibiotic targets the bacteria, so the combination addresses both the inflammatory and infectious parts of the skin problem.
Mechanism Steps
💡 How to Take biomycin cream
Strength: Topical cream containing beclometasone 0.025% w/w and neomycin 0.5% w/w.
Dosage Information
| Adult Dosage | Apply a thin layer of this medicine to the affected skin once or twice daily, or exactly as prescribed by your doctor. The frequency and duration depend on the condition being treated, the size of the area, and your response to treatment. Do not use it for more days than prescribed. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. Children may absorb more corticosteroid through the skin, so this medicine should be used in children only under strict medical supervision and for the shortest possible time. |
| Elderly Dosage | Elderly patients may have thinner skin and are more prone to skin thinning and other side effects. Use the smallest effective amount for the shortest duration, and only under medical supervision. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Renal Impairment | No specific dose adjustment is usually needed for topical use. However, if this medicine is used on large areas or broken skin for a long time, absorbed neomycin could affect kidney function. People with kidney disease should use it only under medical advice. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Hepatic Impairment | No specific dose adjustment is usually needed for topical use. Beclometasone is metabolized in the liver, so people with severe liver disease should use this medicine only under medical supervision. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Maximum Daily Dose | The maximum daily dose depends on the size of the treated area and the prescribed frequency. Do not exceed the amount and frequency recommended by your doctor. For topical use, the usual maximum is a thin layer applied once or twice daily to the affected area only. |
Dosage Timeline
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of biomycin cream
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Other topical corticosteroids | Major | |
| Other topical aminoglycosides | Major | |
| Systemic aminoglycosides | Major | |
| Loop diuretics | Major | |
| Oral or injectable corticosteroids | Moderate | |
| Strong soaps and detergents | Moderate | |
| Other topical antibiotics | Moderate | |
| Moisturizers | Minor | |
| Sunscreen | Minor |
🚨 Major Interactions
- Other topical corticosteroids
- Other topical aminoglycoside antibiotics
- Systemic aminoglycosides such as gentamicin or amikacin
- Loop diuretics such as furosemide
⚡ Moderate Interactions
- Corticosteroid tablets or injections
- Skin irritants such as strong soaps, detergents, or astringents
- Other topical antibiotics such as clindamycin or erythromycin
🍷 Alcohol Interaction
Alcohol does not directly interact with this topical cream. However, alcohol can worsen skin inflammation and dehydration, so it is best to limit alcohol intake while your skin is healing.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to beclometasone, neomycin, or any other aminoglycoside antibiotic","Untreated bacterial skin infections that require systemic antibiotics","Viral skin infections such as chickenpox, shingles, or cold sores","Fungal skin infections such as ringworm or athlete's foot","Acne and rosacea","Use on the face, groin, or underarms unless specifically directed by a doctor","Use in the eyes or on mucous membranes"]
⚠️ Warnings & Precautions
["For external use only. Do not swallow.","Do not use on large areas of the body or for longer than prescribed without medical advice.","Do not cover the treated area with airtight dressings unless your doctor instructs you to.","Avoid contact with the eyes, mouth, and nose.","Use with caution in children, as they may absorb more medicine through the skin.","Use with caution in elderly people and in those with kidney or liver disease.","Stop using the cream and consult a doctor if the skin condition worsens or does not improve after the prescribed course.","Do not use this medicine to treat any condition other than the one for which it was prescribed."]
🤱 Lactation Safety
It is not known whether beclometasone and neomycin pass into breast milk in significant amounts after topical use. To be safe, do not apply this cream to the breasts or nipple area before breastfeeding. If you need to use it on other areas, apply it after feeding and wash your hands thoroughly. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
This medicine is for external use, so accidental overdose is unlikely. If someone swallows this cream, seek medical help immediately. If too much cream is applied to the skin, wash the area gently with soap and water and contact a doctor if you notice any unusual symptoms. Long-term excessive use can lead to skin thinning and absorption into the body, so always follow the prescribed amount and duration.
⏰ Missed Dose
If you miss a dose, apply the cream as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double amount to make up for a missed dose.
Additional Safety Advice
Apply this medicine only to the affected skin and only as prescribed by your doctor. Wash your hands before and after applying it, unless your hands are the treated area. Do not cover the treated area with airtight dressings, plastic wrap, or tight clothing unless your doctor tells you to. Avoid contact with the eyes, mouth, nose, and other mucous membranes. Do not use this medicine on the face, groin, or underarms for long periods because the skin there is more sensitive. Do not use it for more days than prescribed, as long-term use can thin the skin and increase absorption into the body. If you are pregnant, planning pregnancy, or breastfeeding, talk to your doctor before using this medicine. Keep this medicine out of the reach of children. Do not share this medicine with anyone else, even if they have similar skin symptoms.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly people have thinner and more fragile skin, which makes them more prone to skin thinning, stretch marks, and other side effects from corticosteroid creams. Use the smallest effective amount for the shortest possible time, and only under medical supervision. If you have kidney or liver disease, tell your doctor before using this medicine, as absorbed neomycin could affect kidney function.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, talk to your doctor before using this medicine. Topical corticosteroids and neomycin are generally considered low risk when used in small amounts for short periods, but it is best to avoid unnecessary medicine during pregnancy. Your doctor can help you weigh the benefits and risks and suggest alternative treatments if needed.
🏥 Post-Surgery Considerations
If you have recently had surgery, do not apply this cream to surgical wounds unless your surgeon specifically prescribes it. Surgical wounds need special care, and using the wrong cream can increase the risk of infection or delay healing. Always follow your surgeon's instructions for wound care.
🦷 Dental Procedures
This medicine is applied to the skin and does not directly affect dental procedures. However, if you are using it on your face or around the mouth, inform your dentist before any dental work. There are no known interactions between this cream and local anesthetics or other medicines commonly used in dentistry.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
You can usually continue your normal exercise routine while using this medicine. However, if the treated area is on a part of the body that rubs against clothing or equipment, take care to avoid friction and excessive sweating, which can irritate the skin. Shower after exercise to remove sweat, and gently pat the area dry before applying the cream. Avoid swimming in chlorinated pools if the skin is broken or infected, as chlorine can irritate the skin.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is applied to the skin and is unlikely to affect your ability to drive or operate machinery. You can continue your usual work and daily activities. However, if the treated area is on your hands, avoid touching your eyes, mouth, or other people's skin until the cream has dried. If your work involves handling chemicals or irritants, protect the treated area with gloves or appropriate clothing as advised by your doctor.
🛑 When to Stop This Medicine
Stop using this medicine and consult your doctor if the skin condition worsens, if you develop signs of an allergic reaction, or if you notice skin thinning, stretch marks, or new infections. Do not stop suddenly if you have been using it for a long time on a large area, because in rare cases this can cause a flare-up. Always follow your doctor's advice on when to stop.
📅 Long-Term Use Effects
Long-term use of this medicine, especially on large areas or under airtight dressings, can lead to thinning of the skin, stretch marks, and changes in skin colour. Some medicine can be absorbed into the body, which may cause facial puffiness, high blood sugar, or adrenal suppression in rare cases. Prolonged use of neomycin can also increase the risk of allergic contact dermatitis and, if absorbed in significant amounts, kidney or ear problems. To minimize these risks, use the smallest effective amount for the shortest duration prescribed by your doctor and attend follow-up visits as advised.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Regular use of gentle moisturizers helps repair the skin barrier and reduce the need for corticosteroid creams.
Evidence: Well-establishedIdentifying and avoiding allergens or irritants that cause your skin condition can reduce flare-ups.
Evidence: Well-establishedFor more extensive bacterial skin infections, a doctor may prescribe oral antibiotics instead of or in addition to topical treatment.
Evidence: Well-establishedControlled exposure to ultraviolet light under medical supervision may help certain chronic skin conditions.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this topical cream and vaccines. You can receive routine vaccinations while using this medicine. However, if you have a severe skin infection or are unwell, your doctor may advise delaying vaccination until you recover. Always inform your healthcare provider about all medicines you are using before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C.
❌ DON'T
Do not refrigerate unless specifically instructed.
✅ DO
Keep the tube tightly closed when not in use.
❌ DON'T
Do not leave the cap off for long periods.
✅ DO
Keep away from direct sunlight and moisture.
❌ DON'T
Do not store in the bathroom cabinet where it may get damp.
✅ DO
Keep out of the reach of children.
❌ DON'T
Do not transfer the cream to another unmarked container.
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging with the prescription label clearly visible. Keep a copy of your prescription with you in case you need to show it at customs or to a doctor while away. Store the cream at room temperature and protect it from direct sunlight and extreme heat. If you are flying, keep it in your hand luggage so it is not exposed to very low temperatures in the checked baggage. Continue using it as prescribed during your trip, and if you need a refill, consult a local doctor or pharmacist with your prescription.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may notice reduced itching and redness within a few hours to a few days. The full effect usually develops over several days of regular use as prescribed.
A: You should not use this cream on your face unless your doctor specifically tells you to. Facial skin is more sensitive, and prolonged use can cause skin thinning and other side effects.
A: Use it only for the duration prescribed by your doctor. Usually, it is used for short periods. Prolonged use can cause skin thinning, stretch marks, and increased absorption into the body.
A: If you remember soon after the missed dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double amount.
A: This cream should be used during pregnancy only if clearly needed and recommended by your doctor. Avoid using it on large areas or for long periods. Consult your doctor before use.
A: Do not apply this cream to the breasts or nipple area before breastfeeding. If you need to use it on other areas, apply it after feeding and wash your hands thoroughly. Consult your doctor before use.
A: Seek immediate medical help if you develop swelling of the face, lips, tongue, or throat, difficulty breathing, severe skin reactions, worsening infection, ringing in the ears, hearing difficulty, or decreased urine output.
A: Do not stop before the prescribed duration unless your doctor tells you to. Stopping too early may allow the infection or inflammation to return. Follow your doctor's instructions.
🤔 Common Patient Concerns
🔄 Substitutes for biomycin cream
View AllAlternative brands with exact same active ingredient:
-
becmet n creamInd Swift Laboratories Ltd ₹11.72 16.6% CHEAPER
-
beclowin n ointmentWin-Medicare Pvt Ltd ₹11.72 16.6% CHEAPER
-
betawok n creamWockhardt Ltd ₹11.72 16.6% CHEAPER
-
beclocort n creamSun Pharmaceutical Industries Ltd ₹13.97 0.6% CHEAPER
-
mazoderm bn creamNovartis India Ltd ₹14.06 SAME PRICE
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This cream can be used for any skin rash.
Fact: This medicine is only for inflamed skin conditions with a bacterial infection. It should not be used for viral, fungal, or purely allergic rashes without infection. - Myth: More cream means faster healing.
Fact: Applying more than the prescribed amount does not speed up healing and can increase the risk of side effects such as skin thinning. - Myth: It is safe to use this cream for months.
Fact: Prolonged use can cause skin thinning, stretch marks, and absorption into the body. Use it only for the duration prescribed by your doctor. - Myth: This cream can be used on the face for acne.
Fact: This medicine is not for acne and should not be used on the face unless specifically directed by a doctor, because facial skin is more sensitive.
🔄 Alternative Options
Generic Alternatives
- Beclometasone and neomycin topical cream
Brand Alternatives
- Cloben G Cream