biocard at 5mg/50mg tablet - Amlodipine (5mg) + Atenolol (50mg) medicine

Amlokind-AT Tablet: Complete Guide to Uses, Side Effects, and Safety

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🏭 Chemo Biological 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
🤰 Pregnancy Category Not established from the available information. Use only if clearly needed and prescribed by a doctor. Both components may affect the fetus; consult your healthcare provider. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for hypertension and angina.
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Very slow heart rate (below 50 beats per minute) or fainting
  • Difficulty breathing, wheezing, or chest tightness
  • Sudden weight gain or swelling of feet and ankles
  • Severe dizziness or lightheadedness
  • Yellowing of skin or eyes (jaundice)
  • Unusual bruising or bleeding
  • Severe allergic reaction with swelling of face, lips, or throat

If experiencing severe symptoms, call emergency services immediately.

What is biocard at 5mg/50mg tablet used for?

This medicine is a combination of Amlodipine and Atenolol used to treat high blood pressure and prevent angina. It works by relaxing blood vessels and slowing the heart rate. Take it once daily as prescribed.

  • Generic Name: Amlodipine + Atenolol
  • Manufacturer: Chemo Biological
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 biocard at 5mg/50mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एम्लोडिपिन और एटेनोलोल का संयोजन है, जिसका उपयोग उच्च रक्तचाप (हाइपरटेंशन) और एंजाइना (सीने में दर्द) के इलाज के लिए किया जाता है। यह रक्त वाहिकाओं को आराम देकर और हृदय की गति को धीमा करके रक्तचाप को कम करती है। इसे डॉक्टर के निर्देशानुसार प्रतिदिन एक बार लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में थकान, चक्कर आना, सिरदर्द, पैरों में सूजन, धीमी हृदय गति और ठंडे हाथ-पैर शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको बेहोशी, सांस लेने में कठिनाई, या दिल की धड़कन बहुत धीमी लगे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अचानक बंद न करें, क्योंकि इससे एंजाइना या दिल का दौरा पड़ सकता है। शराब से बचें क्योंकि इससे चक्कर और निम्न रक्तचाप बढ़ सकता है। गाड़ी चलाते समय सावधानी बरतें जब तक आपको पता न चल जाए कि यह दवा आप पर कैसा असर करती है। नियमित रूप से रक्तचाप और हृदय गति की जांच कराएं।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 biocard at 5mg/50mg tablet Uses & Benefits

[{"condition":"Hypertension","description":"This medicine effectively lowers blood pressure in adults, reducing the risk of stroke, heart attack, and kidney problems.","evidence":"Well-established"},{"condition":"Angina pectoris","description":"It helps prevent chest pain (angina) by reducing the heart's workload and improving blood flow to the heart muscle.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label to prevent migraines, but evidence is limited.","evidence":"Limited"},{"condition":"Anxiety with palpitations","description":"Atenolol component may be used off-label to manage symptoms of anxiety with rapid heart rate.","evidence":"Limited"}]

Primary treatment for: Hypertension

Also treats: Angina pectoris

📋 Drug Information

Generic Name(s)Amlodipine + Atenolol
Brand NameAmlokind-AT Tablet
ManufacturerChemo Biological
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassCalcium channel blocker + Beta blocker
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day, preferably in the morning.
2
Monitor your blood pressure and heart rate regularly and keep a record.
3
Do not stop this medicine abruptly without consulting your doctor.
4
Inform your doctor if you have asthma, diabetes, or kidney problems.
5
Avoid alcohol as it can increase dizziness and low blood pressure.
6
Report any unusual swelling, difficulty breathing, or very slow pulse immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High blood pressure
This medicine is commonly prescribed for hypertension.
Likely Use
✅
Chest pain (angina)
This medicine helps prevent angina attacks.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAmlodipine is well absorbed orally, with peak plasma concentrations reached in 6-12 hours. Atenolol is incompletely absorbed (about 50%) with peak levels in 2-4 hours. Food does not significantly affect absorption of either component.
DistributionAmlodipine has a large volume of distribution and is highly protein-bound. Atenolol has a low volume of distribution and is minimally protein-bound. Both distribute to tissues, but Atenolol crosses the blood-brain barrier poorly.
Protein BindingAmlodipine: approximately 93% bound to plasma proteins. Atenolol: less than 5% bound.
MetabolismAmlodipine is extensively metabolized in the liver, primarily by CYP3A4. Atenolol is not significantly metabolized and is excreted unchanged by the kidneys.
Half-LifeAmlodipine: 30-50 hours. Atenolol: 6-7 hours.
ExcretionAmlodipine metabolites are excreted mainly in urine. Atenolol is excreted unchanged in urine.
BioavailabilityAmlodipine: 64-90%. Atenolol: approximately 50%.
Onset of ActionAmlodipine: within 24-48 hours for blood pressure reduction. Atenolol: within 1 hour for heart rate reduction.
Peak Plasma TimeAmlodipine: 6-12 hours. Atenolol: 2-4 hours.
Duration of ActionAmlodipine: 24 hours. Atenolol: 24 hours (at usual doses).

How It Works

This medicine combines two active ingredients with complementary actions. Amlodipine blocks L-type calcium channels in vascular smooth muscle, causing vasodilation and reduced peripheral resistance. Atenolol selectively blocks beta-1 adrenergic receptors in the heart, reducing heart rate, contractility, and cardiac output. Together, they lower blood pressure and decrease myocardial oxygen demand.

Mechanism Steps

1
Calcium channel blockade by Amlodipine: Amlodipine inhibits the influx of calcium ions into vascular smooth muscle cells, leading to relaxation and dilation of peripheral arterioles.
2
Beta-1 receptor blockade by Atenolol: Atenolol competitively blocks beta-1 adrenergic receptors in the heart, reducing sympathetic stimulation and decreasing heart rate and contractility.
3
Reduced peripheral resistance and cardiac output: The combined effects lower systemic vascular resistance and cardiac output, resulting in decreased blood pressure.
4
Decreased myocardial oxygen demand: By slowing the heart and reducing contractility, Atenolol lowers oxygen demand, while Amlodipine improves coronary blood flow, together relieving angina.

💡 How to Take biocard at 5mg/50mg tablet

Strength: Tablet containing Amlodipine 5 mg and Atenolol 50 mg.

1Take this medicine orally with a glass of water.
2Swallow the tablet whole; do not crush or chew.
3Take it at the same time each day, preferably in the morning.
4You may take it with or without food.
5Do not stop taking this medicine without consulting your doctor.

Dosage Information

Adult DosageThe usual adult dose is one tablet (Amlodipine 5 mg + Atenolol 50 mg) taken orally once daily, preferably in the morning. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and response to therapy. Do not exceed the prescribed dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially dizziness and bradycardia. Start with a lower dose and monitor closely. Dose must be individualized by a qualified clinician.
Renal ImpairmentIn patients with renal impairment, Atenolol clearance is reduced. Dose adjustment is required based on creatinine clearance. Consult a clinician for individualized dosing.
Hepatic ImpairmentIn patients with hepatic impairment, Amlodipine clearance is reduced. Start with a lower dose and monitor closely. Dose must be individualized by a qualified clinician.
Maximum Daily DoseThe maximum recommended daily dose is one tablet (Amlodipine 5 mg + Atenolol 50 mg) once daily. Do not exceed without medical advice.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With or without food
Take at the same time daily
Food does not significantly affect absorption.
Grapefruit
Avoid
May increase Amlodipine levels and risk of hypotension.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours have passed since the missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with your regular schedule.
📌 More than 12 hours have passed since the missed dose
→ Skip the missed dose.
💡 Do not double the dose to catch up.

⚠️ Side Effects of biocard at 5mg/50mg tablet

✅ Common Side Effects

Fatigue (Common (5-10%))
Usually improves with continued use. If persistent, consult your doctor.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying positions. Avoid driving if affected.
Headache (Common (5-10%))
May resolve on its own. Use acetaminophen if needed, but consult doctor if severe.
Peripheral edema (swelling of ankles/feet) (Common (5-10%))
Elevate legs when sitting. Report if severe or bothersome.
Bradycardia (slow heart rate) (Common (5-10%))
Monitor pulse. If below 50 bpm or symptomatic, contact doctor.
Cold extremities (Common (5-10%))
Keep warm. Usually not dangerous.

🚨 Serious Side Effects

Severe bradycardia or heart block (Rare (<0.1%))
Seek immediate medical attention if you experience fainting, severe dizziness, or very slow pulse.
Bronchospasm (Rare (<0.1%))
Seek immediate medical attention if you have difficulty breathing, wheezing, or chest tightness.
Worsening of heart failure (Rare (<0.1%))
Report sudden weight gain, swelling, or shortness of breath to your doctor immediately.
Severe allergic reaction (angioedema, anaphylaxis) (Very rare (<0.01%))
Call emergency services if you experience swelling of face, lips, throat, or difficulty breathing.

⚠️ Rare Side Effects

Jaundice
Report yellowing of skin or eyes to your doctor immediately.
Thrombocytopenia
Report unusual bruising or bleeding.
Psoriasis-like rash
Consult dermatologist if rash appears.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Verapamil Major
Clonidine Major
NSAIDs Moderate
Insulin Moderate
Digoxin Moderate
CYP3A4 inhibitors Major
Antacids Minor
Grapefruit juice Minor

🚨 Major Interactions

  • Verapamil or Diltiazem
  • Clonidine
  • CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)

⚡ Moderate Interactions

  • NSAIDs (e.g., ibuprofen)
  • Diabetes medications (insulin, oral hypoglycemics)
  • Digoxin

🍷 Alcohol Interaction

Alcohol may enhance the blood pressure-lowering effect of this medicine, leading to dizziness, lightheadedness, and increased risk of fainting. It is advisable to limit or avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Severe bradycardia","Second or third-degree heart block","Cardiogenic shock","Decompensated heart failure","Severe peripheral arterial disease","Known hypersensitivity to Amlodipine or Atenolol","Untreated pheochromocytoma"]

⚠️ Warnings & Precautions

["Do not stop this medicine abruptly, as it may worsen angina or cause a heart attack.","Use with caution in patients with asthma or COPD due to risk of bronchospasm.","May mask symptoms of hypoglycemia in diabetic patients.","May worsen symptoms of peripheral arterial disease.","Use with caution in patients with liver or kidney disease; dose adjustment may be needed.","Avoid driving or operating machinery until you know how this medicine affects you.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]

🤱 Lactation Safety

Amlodipine and Atenolol are excreted in breast milk. Atenolol may cause bradycardia and hypoglycemia in the infant. Breastfeeding is not recommended while taking this medicine unless advised by a doctor.

💊 Overdose Management

Overdose may cause severe hypotension, bradycardia, heart failure, and bronchospasm. Seek immediate medical attention. Treatment is supportive and may include intravenous fluids, atropine, glucagon, and vasopressors. Hemodialysis may be considered for Atenolol removal.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed. Do not stop suddenly, as abrupt withdrawal of Atenolol can worsen angina or cause a heart attack. Avoid driving or operating heavy machinery until you know how this medicine affects you. Inform your doctor if you have asthma, diabetes, kidney or liver disease, or heart failure. Do not use potassium supplements without medical advice. Avoid alcohol as it may increase dizziness and low blood pressure. Keep all appointments for blood pressure and heart rate monitoring.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to dizziness, bradycardia, and falls. Start with a lower dose and monitor closely. Regular assessment of renal function is important.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended during pregnancy unless clearly needed. If you are planning pregnancy, consult your doctor to switch to a safer alternative. Both Amlodipine and Atenolol may affect the fetus.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and affect heart rate and blood pressure during surgery. Do not stop unless advised.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. It may cause dry mouth or interact with local anesthetics containing epinephrine. Monitor blood pressure during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to help control blood pressure.
🥗
Engage in regular moderate exercise like walking or swimming.
😴
Reduce salt intake to less than 5 grams per day.
💧
Avoid smoking and limit alcohol consumption.
🧘
Practice stress-reducing techniques like yoga or meditation.
🌞
Get adequate sleep and maintain a regular sleep schedule.

🏋️ Exercise Considerations

This medicine may cause dizziness or slow heart rate, especially when starting treatment or changing doses. Avoid strenuous exercise until you know how it affects you. Stay hydrated during exercise.

🥗 Diet Recommendations

Follow a DASH diet rich in fruits, vegetables, and whole grains.
Limit sodium intake to less than 5 grams per day.
Include potassium-rich foods like bananas and spinach (unless contraindicated).
Avoid excessive caffeine and alcohol.
Maintain a balanced diet to support heart health.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue, especially when you first start taking it. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal activities with caution.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects or your doctor decides to discontinue, the dose should be tapered gradually to avoid rebound hypertension or angina.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe when monitored. Regular check-ups for blood pressure, heart rate, kidney and liver function are recommended. It may increase the risk of new-onset diabetes and may worsen peripheral arterial disease. Do not stop without medical advice.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet, exercise, and stress reduction can help control blood pressure and may reduce medication needs.

Evidence: Well-established
Other antihypertensive combinations

Alternative combinations like ARBs with beta-blockers or calcium channel blockers may be considered based on patient profile.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, inform your doctor about this medicine before receiving any vaccine. Continue routine vaccinations as recommended.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight and moisture

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or moisture. If traveling across time zones, consult your doctor about adjusting the timing of your dose. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with hypertension and angina
He was prescribed this medicine after his blood pressure remained high on a single drug. Within a few weeks, his blood pressure stabilized and angina episodes reduced. He experienced mild dizziness initially, which improved after a week. He now takes it regularly every morning.
💡 Lesson: Combination therapy can be more effective for blood pressure control, but initial side effects like dizziness may occur and usually subside.
👤 A 62-year-old woman with diabetes and hypertension
She started this medicine and noticed her blood sugar readings were sometimes low without warning symptoms. Her doctor adjusted her diabetes medication and educated her about non-adrenergic signs of hypoglycemia. She now monitors her blood sugar more frequently.
💡 Lesson: This medicine can mask symptoms of low blood sugar in diabetics; regular monitoring and awareness are essential.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Amlodipine starts lowering blood pressure within 24-48 hours, while Atenolol reduces heart rate within 1 hour. Full effects may take 1-2 weeks.

Q: Can I stop taking this medicine if I feel fine?

A: No, do not stop without consulting your doctor. High blood pressure often has no symptoms, and stopping suddenly can cause dangerous rebound effects.

Q: What should I do if I miss a dose?

A: If you remember within 12 hours, take it. If more than 12 hours have passed, skip it and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my diabetes medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for biocard at 5mg/50mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be stopped once blood pressure is normal.
    Fact: High blood pressure often has no symptoms and requires long-term treatment. Stopping suddenly can cause dangerous rebound effects.
  • Myth: This medicine damages the kidneys.
    Fact: Actually, controlling blood pressure protects the kidneys from damage. However, regular monitoring is important.

🔄 Alternative Options

Generic Alternatives

  • Amlodipine 5 mg + Atenolol 50 mg tablet (generic)

Brand Alternatives

  • Amlokind-AT Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Amlodipine + Atenolol","composition":"Amlodipine 5 mg + Atenolol 50 mg","onset":"Within 24-48 hours","duration":"24 hours","notes":"Combination for hypertension and angina."},{"medicine":"Amlodipine alone","composition":"Amlodipine 5 mg","onset":"Within 24-48 hours","duration":"24 hours","notes":"Used when beta-blocker not needed."},{"medicine":"Atenolol alone","composition":"Atenolol 50 mg","onset":"Within 1 hour","duration":"24 hours","notes":"Used when calcium channel blocker not needed."}]

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