biclox d capsule - Ampicillin (NA) + Dicloxacillin (NA) medicine

biclox d capsule - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Kniss Laboratories Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is biclox d capsule used for?

Ampilox Capsule (Ampicillin + Dicloxacillin) is used to treat ANTI INFECTIVES. It contains Ampicillin (NA) + Dicloxacillin (NA), which Ampicillin inhibits bacterial cell wall synthesis by binding to penicillin-bindi. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Ampicillin + Dicloxacillin
  • Manufacturer: Kniss Laboratories Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: B
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š biclox d capsule Uses & Benefits

Treatment of infections caused by susceptible organisms: respiratory tract infections, urinary tract infections, skin and soft tissue infections, osteomyelitis, septicemia.

Off-label uses: Prophylaxis in dental procedures, Treatment of Lyme disease

๐Ÿ“‹ Drug Information

Generic Name(s)Ampicillin + Dicloxacillin
Brand NameAmpilox Capsule
ManufacturerKniss Laboratories Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassPenicillin Antibiotics
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC); protect from moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from the gastrointestinal tract; absorption may be decreased by food.
DistributionDistributes widely into body tissues and fluids, including pleural, peritoneal, and synovial fluids; crosses placenta; enters breast milk.
Protein BindingAmpicillin: 20%, Dicloxacillin: 95-98%
MetabolismAmpicillin: Partially metabolized in liver; Dicloxacillin: Hepatic metabolism to active and inactive metabolites.
Half-LifeAmpicillin: 1-1.8 hours; Dicloxacillin: 0.6-0.8 hours
ExcretionAmpicillin: Primarily renal (90% unchanged); Dicloxacillin: Renal and biliary (30-60% unchanged in urine).
BioavailabilityAmpicillin: 30-55%; Dicloxacillin: 50-85%
Onset of Action1-2 hours
Peak Plasma TimeAmpicillin: 1-2 hours; Dicloxacillin: 1-1.5 hours
Duration of Action6-8 hours

How It Works

Ampicillin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs); Dicloxacillin inhibits cell wall synthesis and is resistant to staphylococcal beta-lactamases.

Mechanism Steps

1Ampicillin binds to PBPs, inhibiting transpeptidation in cell wall synthesis.
2Dicloxacillin binds to PBPs and resists hydrolysis by staphylococcal beta-lactamases.
3Both drugs disrupt cell wall integrity, leading to bacterial lysis and death.

๐Ÿ’ก How to Take biclox d capsule

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of biclox d capsule

โœ… Common Side Effects

  • Nausea
  • Diarrhea
  • Rash
  • Vomiting

๐Ÿšจ Serious Side Effects

  • Anaphylaxis
  • Stevens-Johnson syndrome
  • Clostridioides difficile colitis
  • Seizures

โš ๏ธ Rare Side Effects

  • Hemolytic anemia
  • Interstitial nephritis
  • Agranulocytosis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Methotrexate Major Increased methotrexate toxicity
Warfarin Major Increased bleeding risk
Probenecid Major Decreased renal excretion of penicillins
Oral contraceptives Moderate Reduced contraceptive efficacy
Allopurinol Moderate Increased risk of skin rash
Aminoglycosides Moderate Synergistic antibacterial effect
Chloramphenicol Minor Antagonistic effect
Tetracyclines Minor Antagonistic effect

๐Ÿšจ Major Interactions

  • Methotrexate
  • Warfarin
  • Probenecid

โšก Moderate Interactions

  • Oral contraceptives
  • Allopurinol
  • Aminoglycosides

โ„น๏ธ Minor Interactions

  • Chloramphenicol
  • Tetracyclines

๐Ÿฝ๏ธ Food Interactions

Food decreases absorption; take on empty stomach.

๐Ÿท Alcohol Interaction

No direct interaction; avoid excessive alcohol due to general health.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to penicillins, cephalosporins, or any component.

๐Ÿ“Š Monitoring Parameters

Renal function, hepatic function, CBC, signs of hypersensitivity.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; use with caution.

๐Ÿ’Š Overdose Management

Supportive care; hemodialysis may be effective.

โฐ Missed Dose

Take as soon as remembered; skip if almost time for next dose; do not double.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

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