Betasys Forte 1000mg/125mg Injection - Uses, Price, Side Effects
What is betasys forte 1000mg/125mg injection used for?
Betasys Forte 1000mg/125mg Injection is a combination of Ceftazidime (a cephalosporin antibiotic) and Tazobactam (a beta-lactamase inhibitor). It is used to treat various bacterial infections, including respiratory tract infections, urinary tract infections, skin infections, and intra-abdominal infections. Ceftazidime kills bacteria by inhibiting cell wall synthesis, while Tazobactam prevents bacterial resistance by inhibiting beta-lactamase enzymes.
- Generic Name: Ceftazidime + Tazobactam
- Manufacturer: Systacare Remedies
- Form: Allopathy
- Pregnancy Category: B
- Prescription Required: Yes
๐ betasys forte 1000mg/125mg injection Uses & Benefits
Treatment of hospital-acquired pneumonia, complicated urinary tract infections, complicated intra-abdominal infections, and febrile neutropenia.
Off-label uses: Bone and joint infections, Cystic fibrosis exacerbations
๐ Drug Information
| Generic Name(s) | Ceftazidime + Tazobactam |
| Brand Name | Actacrez 2.25g Injection |
| Manufacturer | Systacare Remedies |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Antibiotic (Cephalosporin + Beta-lactamase inhibitor) |
| Route of Administration | Intravenous (IV) |
| Storage | Store at 20-25ยฐC; protect from light; reconstituted solution stable for 24 hours at room temperature or 7 days refrigerated. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Ceftazidime inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs); Tazobactam inhibits beta-lactamases, preventing ceftazidime degradation.
Mechanism Steps
๐ก How to Take betasys forte 1000mg/125mg injection
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of betasys forte 1000mg/125mg injection
โ Common Side Effects
- Diarrhea
- Nausea
- Vomiting
- Rash
- Injection site reactions
๐จ Serious Side Effects
- Clostridioides difficile colitis
- Seizures
- Anaphylaxis
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Hemolytic anemia
- Thrombocytopenia
- Interstitial nephritis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Probenecid | Moderate | Reduced excretion of ceftazidime |
| Aminoglycosides | Moderate | Increased nephrotoxicity |
๐จ Major Interactions
- Warfarin
- Aminoglycosides
- Chloramphenicol
โก Moderate Interactions
- Probenecid
- Loop diuretics
- Oral contraceptives
โน๏ธ Minor Interactions
- Antacids
- Iron supplements
๐ฝ๏ธ Food Interactions
No significant food interactions (IV administration).
๐ท Alcohol Interaction
No known interaction, but alcohol may increase side effects like dizziness.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to ceftazidime, tazobactam, or other cephalosporins; history of severe allergic reactions to penicillins.
๐ Monitoring Parameters
Renal function, liver function, CBC, signs of superinfection, bleeding (if on warfarin).
๐คฑ Lactation Safety
Excreted in breast milk in low amounts; use with caution.
๐ Overdose Management
Supportive care; hemodialysis may enhance elimination.
โฐ Missed Dose
Administer as soon as remembered; do not double dose.