Bactaz 4000 mg/500 mg Injection - Uses, Price, Side Effects
What is bactaz 4000 mg/500 mg injection used for?
Bactaz 4000 mg/500 mg Injection is a combination antibiotic containing Piperacillin (4000 mg) and Tazobactam (500 mg). Piperacillin kills bacteria by inhibiting cell wall synthesis, while Tazobactam prevents bacterial resistance. It is used to treat moderate to severe bacterial infections including pneumonia, intra-abdominal infections, and urinary tract infections.
- Generic Name: Piperacillin + Tazobactam
- Manufacturer: Sego Lily Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: B
- Prescription Required: Yes
๐ bactaz 4000 mg/500 mg injection Uses & Benefits
Intra-abdominal infections, urinary tract infections, respiratory tract infections, skin and soft tissue infections, septicemia, febrile neutropenia.
Off-label uses: Bone and joint infections, Endocarditis, Meningitis
๐ Drug Information
| Generic Name(s) | Piperacillin + Tazobactam |
| Brand Name | Ahentaz 4.5 Injection |
| Manufacturer | Sego Lily Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Penicillin antibiotic with beta-lactamase inhibitor |
| Route of Administration | Intravenous (IV) infusion |
| Storage | Store at 20-25ยฐC (68-77ยฐF); reconstituted solution stable for 24 hours at room temperature or 48 hours under refrigeration. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Piperacillin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs); Tazobactam irreversibly inhibits beta-lactamases, protecting piperacillin from degradation.
Mechanism Steps
๐ก How to Take bactaz 4000 mg/500 mg injection
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of bactaz 4000 mg/500 mg injection
โ Common Side Effects
- Diarrhea
- Nausea
- Vomiting
- Headache
- Insomnia
- Rash
๐จ Serious Side Effects
- Anaphylaxis
- Stevens-Johnson syndrome
- Clostridioides difficile diarrhea
- Acute renal failure
- Hepatitis
โ ๏ธ Rare Side Effects
- Agranulocytosis
- Hemolytic anemia
- Seizures
- Pseudomembranous colitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Methotrexate | Moderate | Increased methotrexate toxicity |
| Probenecid | Moderate | Decreased renal excretion of piperacillin |
๐จ Major Interactions
- Warfarin
- Methotrexate
- Vecuronium
- Probenecid
โก Moderate Interactions
- Oral contraceptives
- Cyclosporine
- Tacrolimus
โน๏ธ Minor Interactions
- Heparin
- NSAIDs
๐ท Alcohol Interaction
No direct interaction, but alcohol may increase side effects like nausea.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to penicillins, cephalosporins, or beta-lactamase inhibitors.
๐ Monitoring Parameters
Renal function, hepatic function, CBC, signs of hypersensitivity, bleeding, superinfection.
๐คฑ Lactation Safety
Excreted in breast milk in low amounts; use with caution.
๐ Overdose Management
Supportive care; hemodialysis may enhance elimination.
โฐ Missed Dose
Administer as soon as possible; do not double dose.
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
This medicine was effective for me. I followed the doctor's advice.
Found this to be a helpful product. Good results.
Good quality medicine. Satisfied with the outcome.
Helpful and effective medicine as per my experience. Always consult a doctor.
Found this to be a helpful product. Good results.