bacsitam 1000mg/500mg injection - Uses, Price, Side Effects & Substitutes
What is bacsitam 1000mg/500mg injection used for?
Amphy 1500 Injection (Amoxycillin + Sulbactam) is used to treat ANTI INFECTIVES. It contains Amoxycillin (1000mg) + Sulbactam (500mg), which Amoxycillin inhibits bacterial cell wall synthesis by binding to penicillin-bind. Always consult your doctor before use. Take as prescribed.
- Generic Name: Amoxycillin + Sulbactam
- Manufacturer: Baxton Pharmacia
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ bacsitam 1000mg/500mg injection Uses & Benefits
Respiratory tract infections, urinary tract infections, skin and soft tissue infections, intra-abdominal infections, septicemia.
Off-label uses: Prophylaxis in surgery, Lyme disease, leptospirosis.
๐ Drug Information
| Generic Name(s) | Amoxycillin + Sulbactam |
| Brand Name | Amphy 1500 Injection |
| Manufacturer | Baxton Pharmacia |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Penicillin antibiotic with beta-lactamase inhibitor |
| Route of Administration | Intravenous (IV) injection or infusion |
| Storage | Store at room temperature (20-25ยฐC); reconstituted solution stable for 1 hour at room temperature. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Amoxycillin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs); Sulbactam irreversibly inhibits beta-lactamases, protecting amoxycillin from degradation.
Mechanism Steps
๐ก How to Take bacsitam 1000mg/500mg injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of bacsitam 1000mg/500mg injection
โ Common Side Effects
- Diarrhea
- Nausea
- Vomiting
- Skin rash
- Injection site pain
๐จ Serious Side Effects
- Anaphylaxis
- Stevens-Johnson syndrome
- Clostridioides difficile colitis
- Seizures (high doses)
โ ๏ธ Rare Side Effects
- Hemolytic anemia
- Agranulocytosis
- Interstitial nephritis
- Hepatitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Methotrexate | Major | Increased methotrexate toxicity |
| Warfarin | Major | Increased bleeding risk |
| Allopurinol | Major | Increased risk of skin rash |
| Probenecid | Major | Decreased renal excretion of amoxycillin, increased levels |
| Oral contraceptives | Moderate | Reduced contraceptive efficacy |
| Tetracyclines | Moderate | Antagonistic effect (bacteriostatic vs bactericidal) |
| Chloramphenicol | Moderate | Antagonistic effect |
| Antacids | Minor | Reduced absorption (oral forms only) |
| Iron supplements | Minor | Reduced absorption (oral forms only) |
๐จ Major Interactions
- Methotrexate
- Warfarin
- Allopurinol
- Probenecid
โก Moderate Interactions
- Oral contraceptives
- Tetracyclines
- Chloramphenicol
โน๏ธ Minor Interactions
- Antacids
- Iron supplements
๐ฝ๏ธ Food Interactions
No significant food interactions (IV administration)
๐ท Alcohol Interaction
No direct interaction, but alcohol may reduce immune response and increase side effects.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to penicillins or beta-lactam antibiotics; history of cholestatic jaundice/hepatic dysfunction with amoxycillin-sulbactam.
๐ Monitoring Parameters
Renal function, hepatic function, CBC, signs of hypersensitivity.
๐คฑ Lactation Safety
Excreted in breast milk in small amounts; generally considered compatible with breastfeeding.
๐ Overdose Management
Supportive care; hemodialysis may help remove drug.
โฐ Missed Dose
Administer as soon as remembered; do not double dose.