Azikil 250mg Tablet - Uses, Price, Side Effects
What is azikil 250mg tablet used for?
Azikil 250mg Tablet contains Azithromycin, a macrolide antibiotic used to treat various bacterial infections such as bronchitis, pneumonia, sinusitis, pharyngitis, tonsillitis, skin infections, and ear infections. It works by stopping the growth of bacteria, helping the body's immune system to eliminate the infection.
- Generic Name: Azithromycin
- Manufacturer: Maxo Chem Ltd
- Form: Allopathy
- Pregnancy Category: B
- Prescription Required: Yes
๐ azikil 250mg tablet Uses & Benefits
Respiratory tract infections, Skin and soft tissue infections, Otitis media, Pharyngitis/tonsillitis, Urethritis/cervicitis due to Chlamydia trachomatis, Mycobacterium avium complex prophylaxis in HIV
Off-label uses: Acute exacerbation of COPD, Non-gonococcal urethritis, Pertussis, Babesiosis (with atovaquone)
๐ Drug Information
| Generic Name(s) | Azithromycin |
| Brand Name | Azee 500 Tablet |
| Manufacturer | Maxo Chem Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Macrolides |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Binds to 50S ribosomal subunit, inhibiting bacterial protein synthesis.
Mechanism Steps
๐ก How to Take azikil 250mg tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of azikil 250mg tablet
โ Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Headache
๐จ Serious Side Effects
- QT prolongation
- Torsades de pointes
- Severe allergic reactions
- Hepatotoxicity
- Clostridioides difficile-associated diarrhea
โ ๏ธ Rare Side Effects
- Hearing loss (reversible)
- Acute interstitial nephritis
- Pancreatitis
- Stevens-Johnson syndrome
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Digoxin | Moderate | Increased digoxin levels |
| Antacids | Moderate | Reduced azithromycin absorption |
๐จ Major Interactions
- Warfarin (increased INR)
- Ergot derivatives (ergotism)
- Nelfinavir (increased azithromycin levels)
โก Moderate Interactions
- Digoxin (increased digoxin levels)
- Cyclosporine (increased cyclosporine levels)
- Antacids (decreased absorption)
โน๏ธ Minor Interactions
- Theophylline (minor increase)
- Triazolam (minor increase)
๐ฝ๏ธ Food Interactions
Take on empty stomach (1 hour before or 2 hours after food) for optimal absorption; food may decrease absorption slightly.
๐ท Alcohol Interaction
No direct interaction; but alcohol may increase gastrointestinal side effects.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to azithromycin or any macrolide antibiotic, History of cholestatic jaundice/hepatic dysfunction with prior azithromycin use, QT prolongation or concurrent use of QT-prolonging agents
๐ Monitoring Parameters
Liver function tests (LFT), ECG for QT interval if at risk, Signs of hypersensitivity
๐คฑ Lactation Safety
Lactation: Limited data; caution advised. Excreted in breast milk in small amounts.
๐ Overdose Management
Supportive care; no specific antidote. Monitor ECG for QT prolongation.
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.
๐จโโ๏ธ Reviewed by Expert
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Medical Note: Always consult your doctor before switching medications.