azicox cf tablet - Uses, Price, Side Effects & Substitutes
What is azicox cf tablet used for?
Azicef-LB Tablet (Cefixime + Azithromycin) is used to treat ANTI INFECTIVES. It contains Cefixime (250mg) + Azithromycin (200mg), which Cefixime inhibits bacterial cell wall synthesis by binding to penicillin-binding. Always consult your doctor before use. Take as prescribed.
- Generic Name: Cefixime + Azithromycin
- Manufacturer: Coxswain Healthcare
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ azicox cf tablet Uses & Benefits
Respiratory tract infections, urinary tract infections, typhoid fever, gonorrhea, skin and soft tissue infections
Off-label uses: Lyme disease, pertussis, chancroid, granuloma inguinale
๐ Drug Information
| Generic Name(s) | Cefixime + Azithromycin |
| Brand Name | Azicef-LB Tablet |
| Manufacturer | Coxswain Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporin antibiotic + Macrolide antibiotic |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Cefixime inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins; Azithromycin inhibits protein synthesis by binding to 50S ribosomal subunit
Mechanism Steps
๐ก How to Take azicox cf tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of azicox cf tablet
โ Common Side Effects
- Diarrhea
- Nausea
- Vomiting
- Abdominal pain
- Headache
- Dizziness
- Rash
๐จ Serious Side Effects
- Pseudomembranous colitis
- Severe allergic reactions (anaphylaxis)
- Stevens-Johnson syndrome
- Hepatotoxicity
- QT prolongation
- Torsades de pointes
โ ๏ธ Rare Side Effects
- Interstitial nephritis
- Hemolytic anemia
- Thrombocytopenia
- Agranulocytosis
- Pancreatitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased INR and bleeding risk |
| Disulfiram | Major | Disulfiram-like reaction |
| Methotrexate | Major | Increased methotrexate toxicity |
| Ergot derivatives | Major | Ergotism risk |
| Pimozide | Major | QT prolongation risk |
| Oral contraceptives | Moderate | Reduced contraceptive efficacy |
| Antacids | Moderate | Decreased absorption of azithromycin |
| Digoxin | Moderate | Increased digoxin levels |
| Cyclosporine | Moderate | Increased cyclosporine levels |
| Theophylline | Moderate | Increased theophylline levels |
| Vitamin K antagonists | Minor | Possible enhanced anticoagulation |
| Probenecid | Minor | Increased cefixime levels |
๐จ Major Interactions
- Warfarin
- Disulfiram
- Methotrexate
- Ergot derivatives
- Pimozide
โก Moderate Interactions
- Oral contraceptives
- Antacids
- Digoxin
- Cyclosporine
- Theophylline
โน๏ธ Minor Interactions
- Vitamin K antagonists
- Probenecid
๐ฝ๏ธ Food Interactions
Cefixime: Food delays absorption; Azithromycin: Food decreases absorption (take on empty stomach)
๐ท Alcohol Interaction
Avoid alcohol; may increase risk of hepatotoxicity and disulfiram-like reaction
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to cephalosporins, macrolides, or any component; history of cholestatic jaundice/hepatic dysfunction with azithromycin
๐ Monitoring Parameters
Renal function, hepatic function, CBC, signs of superinfection, QT interval if risk factors
๐คฑ Lactation Safety
Cefixime: Excreted in breast milk in low amounts, generally considered safe; Azithromycin: Excreted
๐ Overdose Management
Supportive care; no specific antidote; consider gastric lavage if recent ingestion
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose; do not double dose